Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, November 11 at 2:00 PM ET

Register Free →

This Government Contract opportunity from Department Of Defense was posted on August 11, 2016. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

DARPA Biological Technologies Office EZ BAA

Awarded
DARPA-BAA-16-08Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

AI Contract Overview

Show more

Modification 1 to DARPA-BAA-16-08, the Biological Technologies EZ Broad Agency Announcement, clarifies that the Defense Advanced Research Projects Agency is specifically soliciting innovative research proposals from nontraditional defense contractors. The Biological Technologies Office seeks to leverage biology, engineering, and computer science to solve intractable national security problems, focusing on emerging technical areas such as synthetic biology, infectious disease, human performance, and human-machine interfaces. The agency is prioritizing unconventional, creative, and agile approaches that enable revolutionary advances rather than evolutionary improvements to existing technology. Multiple awards may be granted based on proposal quality, program balance, and fund availability. The solicitation encourages the use of fixed price contracts or Other Transactions to provide commercial-like flexibility, while entities seeking cost-reimbursable contracts, grants, or cooperative agreements are directed to the Office-Wide Biological Technologies solicitation. DARPA reserves the right to impose publication restrictions if the research discloses critical military system characteristics or unique manufacturing technologies. The response deadline for this opportunity is November 22, 2016.

General Info

Contract Value

$749,986

NAICS

541711 - Research and Development in Biotechnology

Place of Performance

VA, USA

Set-Aside

NONE

Award Issued Date

Documents

2

DARPA BAA 16-08 Amendment 1

DOCX, High priority: read this first26 pages · amendment
High

DARPA Biological Technologies EZ BAA

PDF, High priority: read this firstbaa
High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

1 update
PhaseAwarded
Posted

Combined Synopsis

Notice updated

The notice description changed.

Awarded

Contract was awarded

Submission Closed

Find active opportunities like this

Get full access to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

Show more
AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
Contacts1 person available
OfficeARLINGTON, VA, 222032114, USA
Office AddressARLINGTON, VA, 222032114, USA
Contacts
Philip LeePresident

Full Description

Show more
The purpose of modification 1 to DARPA-BAA-16-08, the Biological Technologies EZ Broad Agency Announcement, is to clarify the target audience and provide updated award information. Sections 1, Funding Opportunity Description, and 2, Award Information, are updated as follows: 1. FUNDING OPPORTUNITY DESCRIPTION The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative research proposals of interest to the Biological Technologies Office (BTO). This funding opportunity is seeking proposals from nontraditional defense contractors. The definition of a nontraditional defense contractor can be found within the Defense Procurement Acquisition Policy (DPAP): http://www.acq.osd.mil/dpap/dars/dfars/html/current/252212.htm. All other entities are instructed to respond to BTO's Office-Wide Biological Technologies solicitation which can be found at http://www.darpa.mil/work-with-us/opportunities. The mission of BTO is to leverage biology as a technology to solve intractable problems. BTO seeks to leverage advances in engineering and computer science to drive and reshape biotechnology for national security. To achieve this vision, BTO is interested in a range of emerging technical areas, including but not limited to human-machine interfaces, human performance, infectious disease, and synthetic biology. The overarching goal is to develop, demonstrate, and transition biologically-based technologies as part of the national security toolkit. Proposed research must enable revolutionary advances in science, technologies, or systems. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of the art. BTO seeks unconventional approaches that are outside the mainstream, challenge assumptions, and have the potential to radically change established practice. Efforts should be creative and agile both in terms of the technologies proposed and in the structure of the approach. Additional information on BTO can be found at http://www.darpa.mil/about-us/offices/bto. 2. AWARD INFORMATION Multiple awards are possible. The amount of resources made available under this BAA will depend on the quality of the proposals received and the availability of funds. The Government reserves the right to select for negotiation all, some, one, or none of the proposals received in response to this solicitation, and to select only portions of proposals for award. Awards under this BAA will be made to proposers on the basis of the evaluation criteria listed below in Section 5, and program balance, to provide overall value to the Government. The Government reserves the right to remove proposers from award consideration should the parties fail to reach agreement on award terms, conditions and cost/price within a reasonable time or the proposer fails to timely provide requested additional information. Proposers looking for innovative, commercial-like contractual arrangements are encouraged to consider requesting Other Transactions. To understand the flexibility and options associated with Other Transactions, consult Section 4.3.2.3. The intent of this solicitation is to encourage proposals from nontraditional defense contractors seeking fixed price contracts or Other Transactions as award instruments. The Government contracting officer shall determine which of these award instruments is appropriate and negotiate terms and conditions with selectees as applicable. Applicants seeking alternate funding vehicles (e.g., cost-reimbursable procurement contracts, cooperative agreements, and grants) should respond to BTO's Office-Wide Biological Technologies solicitation which can be found at http://www.darpa.mil/work-with-us/opportunities. DARPA will apply publication or other restrictions, as necessary, if it determines that the research resulting from the proposed effort will present a high likelihood of disclosing performance characteristics of military systems or manufacturing technologies that are unique and critical to defense. Any award resulting from such a determination will include a requirement for DARPA permission before publishing any information or results on the program. For more information on publication restrictions, see the section below on Fundamental Research. BAA Package Amendment 1 with these changes is attached.

More opportunities from Department Of Defense → Defense Advanced Research Projects Agcy

Same awarding agency

NAICS: 541714
New
Federal
High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)
Solicitation # DARPA-PA-27-01
The High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE) program, solicited by the DARPA Biological Technologies Office under DARPA-PA-27-01, seeks to develop an in-silico capability for mapping all protein-protein interactions. The primary objective is to create a comprehensive human interactome hypercatalog capturing over 10 million new interactions, shifting from static biomarkers to dynamic, context-aware interactomes. The utility of this capability will be demonstrated by identifying novel diagnostic and therapeutic targets for traumatic brain injury. Awards will be issued as Other Transaction (OT) for Research agreements with fixed, payable milestones. The program is structured in two phases, with Phase 1 estimated at 12 months and Phase 2 anticipated at 18 months, though current awards are limited to Phase 1. Proposers, including large and small businesses, universities, and research institutions, must submit a maximum six-page unclassified abstract via the Broad Agency Announcement Tool by November 5, 2026, to be considered for an Oral Proposal Package due December 11, 2026. Evaluation is based on technical comprehension, technical ability, and the realism of the cost rough order of magnitude. Prime proposers must be registered in the System for Award Management and demonstrate CMMC Level 1 compliance. Performance will be managed through a Task Description Document and a milestone-based payment schedule, with invoicing processed through the Wide Area Workflow system. Security requirements include the Fundamental Research Risk-Based Security Review Process for all senior and key personnel.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 23 hours ago

DEADLINE

in 7 days
View Details
NAICS: 541715
New
Federal
Future Announcement: Quantum Computing – Applications Workshops (QC-AW)
Solicitation # DARPA-SN-27-14
Special Notice DARPA-SN-27-14, issued by the Defense Advanced Research Projects Agency (DARPA) Multi X Office, serves as an advance notification of the agency's intent to host a series of Quantum Computing Applications Workshops (QC-AW) beginning no later than January 2027. The primary objective of these workshops is to determine the commercial impact of future utility-scale quantum computers by collaborating with quantum-algorithm experts, end-users, financial stakeholders, and hardware experts. This effort aims to identify high-value use cases, accelerate industrially relevant quantum advantage, and establish a path toward pricing the value of quantum computations through the development of new benchmarks for commercial application workloads. This notice is issued solely for information and program planning purposes and does not constitute a formal solicitation for proposals or proposal abstracts. Interested parties should monitor sam.gov for future Requests for Information (RFI) describing the workshops. All administrative and technical inquiries should be directed to the QBI SN Coordinator at [email hidden], with Micah Stoutimore, Ph.D., serving as the technical point of contact. The notice explicitly states that no classified information should be included in any response. The response deadline for this notice is December 30, 2026, and the associated NAICS code is 541715.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 23 hours ago

DEADLINE

in 2 months
View Details
NAICS: 541715
New
Federal
Atomically Precise Molecules (APM)
Solicitation # DARPA-PS-26-141
The Atomically Precise Molecules (APM) program, solicitation DARPA-PS-26-141, is a Department of Defense initiative managed by the DARPA Multi X Office. The program seeks innovative synthesis techniques for programmable precision polymers (PPPs) to develop revolutionary nonlinear optical (NLO) materials. The primary objective is to create scalable materials with strictly controlled monomer sequences and composition, culminating in a prototype demonstration integrated into a government-provided electro-optic modulator. Key technical goals include achieving modulation greater than 1THz and meeting specific optical loss metrics. The program is structured in two phases, with an anticipated start date of April 1, 2027, and a performance period extending through 18 months. Awards will be issued as Other Transaction for Prototype Agreements, with payments tied to a schedule of milestones and processed via the Wide Area Workflow system. Proposals are evaluated based on scientific and technical merit, relevance to the DARPA mission, budget realism, and the capability for technology transition. Strict eligibility requirements apply, as non-US organizations are prohibited from participating. Additionally, performers must adhere to rigorous cybersecurity standards, including CMMC Level 2 self-certification and compliance with NIST SP 800-171 R2 controls for the protection of Controlled Unclassified Information. Full proposals, including technical, management, and pricing volumes, must be submitted through the Broad Agency Announcement Tool by December 18, 2026.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

2 days ago

DEADLINE

in about 2 months
View Details
NAICS: 541715
New
Federal
Protein Palace Proposers Day
Solicitation # DARPA-SN-27-01
The Defense Advanced Research Projects Agency (DARPA) is initiating the Protein Palace program to develop a universal, tunable protein purification platform. This initiative aims to replace the traditional lock-and-key paradigm with a system capable of purifying multiple proteins from a single system by leveraging unique physicochemical characteristics to improve biomanufacturing specificity, generalizability, and scalability. The program is structured into two distinct phases: a 24-month Phase 1 focused on proving the feasibility of specificity and generalizability by separating eight different proteins, followed by an 18-month Phase 2 focused on scalability and throughput, which requires demonstrating the platform on two additional proteins that are difficult to purify using current state-of-the-art methods. To support this effort, DARPA is hosting an in-person Proposers Day on November 17, 2026, from 9:00 a.m. to 4:00 p.m. ET at the Executive Conference Center in Arlington, Virginia. This event is unclassified, and all attendees must provide government-issued photo identification. While the current Special Notice DARPA-SN-27-01 and its subsequent amendment serve as information and planning tools rather than a formal solicitation, DARPA anticipates releasing the full solicitation on sam.gov prior to the event. Interested parties must meet the registration deadline of November 9, 2026, to attend the session.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

6 days ago

DEADLINE

in 11 days
View Details
NAICS: 541715
New
Federal
Solid-State Energy Conversion from Heat to Electricity Request for Information (RFI)
Solicitation # DARPA-SS-27-01
The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office is issuing Request for Information (RFI) DARPA-SS-27-01 to explore the current state of the art and technological limitations of solid-state direct thermal-to-electric energy conversion. This initiative focuses on systems that convert temperature differentials into electrical energy without the use of mechanical moving parts, such as turbines or pistons. The primary objective is to gather quantitative data on performance across various operating temperatures, identify limiting factors, and determine the most viable use cases to inform the planning of future research and development programs. This RFI is for planning purposes only and does not constitute a formal solicitation for proposals. Interested parties must submit unclassified responses by 4:00 p.m. Eastern on November 23, 2026, via email to [email hidden]. Submissions must adhere to specific formatting guidelines, including a 12-point font and a structured layout consisting of a cover sheet, a five-page technical description, a two-page bibliography, and a one-page summary of prior research. Respondents are encouraged to include technical models, test data, and the current Technology Readiness Level (TRL) of their technologies, while ensuring any proprietary information is clearly labeled.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

6 days ago

DEADLINE

in 25 days
View Details
NAICS: 541715
New
Federal
Cattle Run Proposers Day Announcement
Solicitation # DARPA-SN-27-03
The Defense Advanced Research Projects Agency (DARPA) is hosting a Proposers Day for the Cattle Run program on November 10, 2026, at the DARPA Conference Center in Arlington, Virginia. This event serves as an informational forum to discuss the development of autonomous spacecraft utilizing solar sails or other renewable propulsion systems to enable cost-effective cislunar constellations. The program is structured in phases, beginning with the rapid development and launch of a demonstrator spacecraft below geosynchronous earth orbit to validate acceleration, vehicle control, and autonomous Guidance, Navigation, and Control (GNC), followed by the deployment of multiple spacecraft for cislunar operations. Registration for the event must be completed by November 4, 2026. Attendance is strictly limited to U.S. Citizens, who must submit a U.S. Citizenship Verification form (DARPA eForm 104). Additionally, all attendees and potential proposers must meet CMMC Level 2 requirements, incorporating the 110 security requirements of NIST SP 800-171 Rev 2 for the protection of Controlled Unclassified Information, with verification performed via the Supplier Performance Risk System. While this notice provides critical program details and networking opportunities, including one-on-one sessions with Program Manager Steven Chambers, it does not constitute a formal solicitation for proposals.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

6 days ago

DEADLINE

in 6 days
View Details
NAICS: 541715
New
Federal
Young Faculty Award (YFA) 2027
Solicitation # DARPARA2701
The Young Faculty Award (YFA) 2027, solicitation DARPARA2701, is a competitive funding opportunity managed by the DARPA Defense Sciences Office. The program is designed to engage early-career researchers at U.S. academic or non-profit research institutions to develop innovative, unclassified basic research that enables transformative national security capabilities for the Department of War. Eligible Principal Investigators must be in a tenure-track position, have achieved tenure within the last three years, or be within twelve years of receiving their doctorate. To ensure the program reaches rising stars, PIs are ineligible if they have previously received more than 500,000 dollars from DARPA or 1.25 million dollars from all Department of War sources combined. Funding is structured around a 24-month base period with a maximum of 500,000 dollars, with a total potential award value of up to 1.225 million dollars including option periods. These options include a 12-month Director's Fellowship and a U.S. Citizen Graduate Student option of up to 225,000 dollars. Proposals are evaluated primarily on overall scientific and technical merit, focusing on innovation, feasibility, risk management, and the expertise of the technical team. Submissions must follow a strict multi-volume format, including a mandatory one-page executive summary due November 5, 2026, and full proposals due January 13, 2027. All personnel must be employed at U.S. institutions, and awardees must comply with federal regulations regarding organizational conflicts of interest and electronic invoicing via Wide Area Work Flow or the Automated Standard Application for Payments system.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

6 days ago

DEADLINE

in 3 months
View Details

Earlier notices in this NAICS code

Posted before this notice, open and closed

Find Active Opportunities Like This

Get AI-powered intelligence on the opportunities still open

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Miguel
Hillary
Keith Deutsch
Christine

Join 750+ contractors already using CLEATUS