This Solicitation opportunity from Department Of Health And Human Services was posted on October 22, 2024. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

Democratized Engineering of Cells Informed by Dynamic Evidence (DECIDE) Exploration Topic

Closed

ARPA-H-MAI-24-01-07Federal

Submission Closed11/18/2024, 05:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

International

Science, Technology & Innovation Data ProviderThis subcontract opportunity with the Government of Canada seeks a Science, Technology and Innovation Data Provider to support prime contractors on Public Services and Procurement Canada information product projects. The selected provider will be responsible for delivering technical datasets, innovation reports, patent data, technical specifications, and comprehensive R&D trend analysis. A critical requirement for this engagement is the provider's ability to enter into a Provider’s Master License Agreement. The project falls under NAICS code 541715 and will be performed within Canada. Interested parties must submit their responses by the deadline of March 31, 2027. This contract focuses on equipping prime contractors with the necessary technical data and innovation metrics to enhance the delivery of government information products.

Government of Canada / Gouvernement du Canada

POSTED

DEADLINE

Highway Safety Research & AnalysisThis subcontract opportunity involves providing specialized research and analysis for prime contractors working on South Dakota Department of Transportation highway safety projects. The primary objective is to evaluate flagger operations to identify safety gaps and establish effectiveness metrics. The selected provider will utilize traffic simulation software to generate data-driven operational recommendations and deliver comprehensive research reports and data analysis summaries. The project is managed under the South Dakota State Government with a response deadline of December 17, 2026. Classified under NAICS code 541715, the contract focuses on technical research and analysis to enhance highway safety protocols within the state.

South Dakota State Government

POSTED

DEADLINE

Computer Vision Algorithm Development for Aerial RefuelingThis subcontract for the U.S. Air Force focuses on the development and training of computer vision AI/ML models to support aerial refueling projects. The scope of work involves implementing object detection and tracking for aircraft and refueling booms, as well as utilizing spatial analysis to ensure precise alignment measurements. To execute these tasks, the contractor must utilize high-compute GPU clusters and advanced AI frameworks to train models based on aerial footage. The project is designated as a Total Small Business Set-Aside under NAICS code 541715, specifically targeting firms with fewer than 500 employees. Key deliverables include the final trained AI models, all associated source code, and comprehensive validation reports. Due to the nature of the defense work, strict adherence to DFARS 252.204-7012 and CMMC cybersecurity standards is mandatory. Responses are due by November 25, 2026.

POSTED

DEADLINE

Optical Design & Photonics ConsultingThis subcontract for Optical Design and Photonics Consulting supports U.S. Navy Office of Naval Research HUD projects by providing specialized optical engineering and design services for prime contractors. The scope of work involves utilizing Zemax or Code V software to design light-engine configurations, holographic optical elements, and waveguides. Key deliverables include feasibility analyses, simulation reports, and detailed optical design specifications. The opportunity is a total small business set-aside under NAICS code 541715, specifically mandated for SBIR/STTR entities with fewer than 500 employees. Contractors must adhere to NIST SP 800-171 cybersecurity requirements to ensure data protection. The response deadline for this requirement is November 25, 2026.

POSTED

DEADLINE

Information Assurance (IA) and Secure Data Exchange SpecialistThis subcontract opportunity for the U.S. Air Force focuses on research and development for Technical Data Package modernization projects. The selected specialist will develop technical frameworks for secure data exchange, conduct feasibility studies on Information Assurance protocols, and design secure transmission workflows. Key deliverables include secure exchange architecture designs and technical feasibility reports intended to support prime contractors. The contract is a Total Small Business Set-Aside under NAICS code 541715, specifically mandating SBIR/STTR compliance for firms with fewer than 500 employees. Due to the sensitive nature of the work, strict adherence to ITAR and EAR regulations is required, and all data handling systems must be CMMC-compliant. Responses are due by November 25, 2026.

POSTED

DEADLINE

Technical Research Subcontractor / ConsultantThis subcontract opportunity, issued by the U.S. Air Force under the Department of Defense, seeks a Technical Research Subcontractor or Consultant to support prime contractors on Department of War SBIR projects. The selected entity will be responsible for conducting specialized research and technical analysis to determine feasibility, developing methods to meet technical objectives, and delivering comprehensive data and research findings for final reports. The contract is a total small business set-aside under NAICS code 541715, requiring the subcontractor to have fewer than 500 employees. Key compliance requirements include adherence to CMMC standards for handling Controlled Unclassified Information and Federal Contract Information, the implementation of OCI mitigation plans, and strict following of protocols regarding Recombinant DNA or Human and Animal Subjects. Responses are due by November 25, 2026.

POSTED

DEADLINE

Research Institution Partner (Non-Profit)This subcontract opportunity is for a registered non-profit research institution to partner with prime contractors on U.S. Air Force STTR projects. The primary objective is to conduct core scientific research to evaluate the technical feasibility of cyber resiliency within edge computing environments. Selected partners will be expected to leverage university laboratories, high-performance computing clusters, and specialized academic research software to produce research data, peer-reviewed findings, and contributions to technical reports. The opportunity is designated as a total small business set-aside under the SBIR/STTR mandate for organizations with fewer than 500 employees, falling under NAICS code 541715. Interested parties must submit their responses by November 25, 2026, at 5:00 PM. This effort is managed through the U.S. Department of Defense on behalf of the U.S. Air Force.

POSTED

DEADLINE

Edge and Fog Computing Architecture SpecialistThis subcontract opportunity for the U.S. Air Force focuses on research and development for cyber resiliency projects, specifically targeting the design of resilient architectures for fog and edge computing devices. The selected provider will be responsible for conducting feasibility studies, establishing technical milestones, and utilizing edge gateways, fog computing nodes, and embedded hardware. Key deliverables include a technical feasibility report and a Final Scientific or Technical Report. The project is a total small business set-aside under NAICS code 541715, requiring the contractor to have fewer than 500 employees. Due to the sensitive nature of the work, strict security compliance is mandatory, including CMMC Level 2 and adherence to NIST SP 800-171 and NIST SP 800-172 standards. Responses are due by November 25, 2026.

POSTED

DEADLINE

Quantum Algorithm & Benchmark DevelopmentThe Quantum Algorithm and Benchmark Development subcontract involves performing technical research and development for prime contractors on projects for the Defense Advanced Research Projects Agency. The scope of work focuses on developing benchmark instances for commercial application workloads, defining resource estimates, and translating high-value use cases into technical quantum algorithm requirements. These tasks will be executed using quantum computing simulators or early-stage quantum hardware, requiring specialized expertise in algorithm optimization and quantum complexity theory. The primary objective of the contract is the delivery of validated commercial application benchmarks. This opportunity is categorized under NAICS code 541715 and is associated with the Department of Defense. Interested parties should note the response deadline of December 30, 2026.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Research Institution / University Partner (STTR)This subcontract opportunity is for a Research Institution or University Partner to support prime contractors on Department of Defense 2027 SBIR/STTR Phase I projects for the U.S. Air Force. The selected partner will be responsible for performing fundamental research, technical validation, and experiments to determine the feasibility of proposed concepts. Key deliverables include contributing to the Phase I technical volume, providing research data, and submitting detailed technical reports and feasibility findings. The solicitation was posted on October 28, 2026, with a response deadline of November 25, 2026. This is a total small business set-aside under the SBIR/STTR mandate for entities with fewer than 500 employees, falling under NAICS code 541715. The primary objective is to provide the academic and analytical rigor necessary to validate technical concepts during the initial phase of the program.

POSTED

DEADLINE

Specialized Cleaning Agent DevelopmentThis subcontract for the U.S. Navy involves the research and development of a specialized cleaning agent designed for TDR Tank Level Indicator projects. The selected contractor will analyze contaminants and formulate non-corrosive chemical compositions that are compatible with naval tank materials, with a strict requirement that no hexavalent chromium is used in the process. The project necessitates the use of laboratory facilities for chemical synthesis and material compatibility testing, culminating in the delivery of sample agents and detailed formulation reports. This opportunity is a Total Small Business Set-Aside under NAICS code 541715, specifically adhering to SBIR/STTR mandates for companies with fewer than 500 employees. Interested parties must submit their responses by November 25, 2026, to support prime contractors operating under the U.S. Department of Defense.

POSTED

DEADLINE

Distributed Engineering Testing and Analysis ServicesThe Distributed Engineering Testing and Analysis Services subcontract is a small business set-aside opportunity with the Naval Surface Warfare Center under the Department of Defense. The project focuses on performing distributed engineering tests to validate system performance for prime contractors on Navy NSWC PCD projects. Work will be performed in Panama City Beach, Florida, under NAICS code 541715. The scope of work involves executing Reliability Centered Maintenance and system safety analysis in accordance with MIL-STD-882E and MIL-STD-3034A. Utilizing telemetry systems and distributed testing rigs, the contractor is responsible for delivering comprehensive test reports, safety analysis documents, and RCM plans. Responses for this opportunity are due by December 3, 2026.

Naval Surface Warfare Center

POSTED

about 8 hours ago

DEADLINE

in about 1 month

AI Contract Overview

The Democratized Engineering of Cells Informed by Dynamic Evidence (DECIDE) Exploration Topic is a solicitation initiative launched by the Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services. The primary objective of this exploration topic is to facilitate access to clinically validated curative cell therapies for pediatric patients suffering from rare genetic diseases. This will be achieved by developing innovative quality assurance mechanisms in Academic Medical Centers. The initiative represents an expansion of the funding strategies employed by ARPA-H's Resilient System Office, as detailed in the appended sections of the Master Announcement Instructions ARPA-H-MAI-24-01. A draft solicitation was amended on October 11, 2024, updating the proposal submission deadline to November 18, 2024, at 12:00 PM EST, and revising the anticipated release date to October 22, 2024. The solicitation was officially posted on October 22, 2024. The National Institutes of Health's most advanced research unit, ARPA-H, is responsible for this solicitation. The solicitation has been classified under the NAICS code 541715, implying a focus on research and development in the physical, engineering, and life sciences. The procurement process is active, and potential respondents are directed to submit their proposals by the stated deadline. The solicitation does not specify a set-aside type, suggesting an open competition for providing solutions related to this initiative. The office managing this solicitation is located in Bethesda, Maryland, USA.

General Info

ARPA-H seeks proposals for curative cell therapies for pediatric rare genetic diseases.

Agency

Department Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

MD, USA

Set-Aside

NONE

Documents

ARPA-H-MAI-24-01-07 DECIDE Exploration Topic

rfp

High

ARPA-H-MAI-24-01-07 DECIDE Exploration Topic

rfp

High

ARPA-H-MAI-24-01-07 Task Description Document (TDD)

sow

High

ARPA-H-MAI-24-01-07 Volume 1 - Administrative and National Policy Requirements

specifications

High

ARPA-H-MAI-24-01-07 Volume 1: Administrative & National Policy Requirements

specifications

High

ARPA-H-MAI-24-01-07 Volume 1: Basis of Estimate

specifications

High

ARPA-H-MAI-24-01-07 Volume 1: Basis of Estimate

specifications

High

ARPA-H-MAI-24-01-07 Volume 1 Proposal Template

sow

High

ARPA-H-MAI-24-01-07 Volume 1 - Task Description Document (TDD)

sow

High

ARPA-H-MAI-24-01-07 Volume 1 Technical & Management Proposal Template

sow

High

ARPA-H RSO Exploration Topic Model OT Agreement

contract-document

High

ARPA-H RSO Exploration Topic Model OT Agreement

contract-document

High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

1 update

PhaseClosed

PostedOct 8

Solicitation

Notice updatedOct 11

The notice description changed.

Response DeadlineNov 18

Deadline has passed

Submission Closed

11/18/2024, 05:00:00 PM UTC

Find active opportunities like this

Get full access to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

AgencyDepartment Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH

Contacts1 person available

OfficeBethesda, MD, 208920004, USA

Organization / AgencyDepartment Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH

Office AddressBethesda, MD, 208920004, USA

Contacts

contact@example.gov

Full Description

10/22/2024: Final solicitation posted

Amendment 1 to Draft Solicitation (10/11/2024): The purpose of this amendment is to update the Proposal Due Date to November 18, 2024 at 12pm EST. The anticipated solicitation release date was also updated to October 22, 2024.

Overview: ARPA-H is launching an Exploration Topic that aims to enable pediatric patients with rare genetic diseases to access clinically validated curative cell therapies by advancing novel quality assurance mechanisms at Academic Medical Centers (AMC). This ET expands the Resilient System Office’s (RSO) funding approach associated with the interest areas included within Appendix A to the Master Announcement Instructions, ARPA-H-MAI-24-01.