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Efficacy Study – Adenine Diet-Induced Kidney Disease Model

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The contract outlines a preclinical efficacy study to evaluate a NNMT inhibitor in a mouse model of adenine-induced chronic kidney disease, focusing on therapeutic assessment through controlled dosing, longitudinal monitoring, and systematic sample collection. The study requires detailed protocols for administering the inhibitor, tracking disease progression via biochemical and histological endpoints, and analyzing the resulting data to determine efficacy, with all procedures aligned to industry standards for preclinical research. The work is to be performed under a subcontract arrangement, with the National Institutes of Health under the Department of Health and Human Services as the overseeing entity, and is classified under NAICS code 541690, indicating it falls within other scientific research and development services. Responses are due by August 19, 2026, following a posting date of August 4, 2026.

General Info

Preclinical study of NNMT inhibitor in mouse kidney disease model, supervised by NIH, responses due August 19, 2026.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541690 - Other Scientific and Technical Consulting ServicesView NAICS

Place of Performance

MD

Set-Aside

NONE

Documents

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
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ContactsNo contact information available

Full Description

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Conduct preclinical efficacy study of NNMT inhibitor in adenine-induced chronic kidney disease mouse model, including dosing, monitoring, sample collection, and data analysis.

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