Fast Healthcare Interoperability Resources (FHIR) Server

The Food and Drug Administration is seeking a Fast Healthcare Interoperability Resources (FHIR) server solution to enhance the scalability of the BEST IM Platform, enabling seamless integration with a wide array of healthcare entities including regional and state health information exchanges, pharmacies, and registries. The required system must accommodate diverse technical capabilities across organizations, many of which may not yet support FHIR standards, necessitating a flexible, robust intermediary that can bridge legacy and modern systems. Given the complexity and cost of developing such interoperability features in-house, the preference is for an established commercial FHIR server platform with proven reliability, such as IRIS for Health, which has demonstrated long-term performance and integration success in similar environments. The agency is not pursuing custom development but instead aims to leverage existing, commercially validated FHIR server technologies to ensure timely deployment and operational efficiency. The opportunity, forecasted on May 25, 2026, falls under NAICS code 423430 and is managed by the FDA’s Center for Biologics Evaluation and Research. The procurement is being led by the CBER Acquisition Liaison, with the contracting officer position yet to be finalized. While specific geographic performance locations are not detailed, the solution must be capable of supporting nationwide health data exchange needs. The focus is on acquiring a ready-to-deploy, scalable infrastructure that reduces time-to-market and minimizes implementation risk while ensuring secure, standards-based communication across heterogeneous healthcare systems.