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Genomic Data Generation Center for the Gabriella Miller Kids First Pediatric Research Program (U24 Clinical Trial Not Allowed)

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RFA-RM-27-008Grant

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The National Institutes of Health is seeking proposals under solicitation RFA-RM-27-008 to establish Genomic Data Generation Center(s) for the Gabriella Miller Kids First Pediatric Research Program. The primary objective is the rapid production of high-quality sequence and variant data from human specimens related to pediatric conditions, such as congenital anomalies and childhood cancers. This includes the generation of genome-wide, RNA, and long-read DNA and RNA sequencing, as well as chromatin accessibility data and genome-wide methylation profiling. All resulting data will be processed and harmonized by the Kids First Pediatric Data Resource Center to be hosted on a public-facing, cloud-based platform. This infrastructure is designed to allow the broader research community to search, analyze, and share annotated genomic and phenotypic datasets to foster collaboration in pediatric research. Interested parties must submit their responses by the deadline of January 9, 2027.

General Info

NIH seeks proposals for pediatric genomic data generation centers by January 9, 2027.

Agency

National Institutes Of Health → Rmod

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Not specified

Set-Aside

NONE

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Organization & Contact Information

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AgencyNational Institutes Of Health → Rmod
ContactsNo contacts available
OfficeUSA
Organization / AgencyNational Institutes Of Health → Rmod
Office AddressUSA
ContactsNo contact information available

Full Description

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The purpose of this Notice of Funding Opportunity (NOFO) is to support the Genomic Data Generation Center(s) for the Gabriella Miller Kids First Pediatric Research Program to support rapid generation of high quality sequence and variant data (e.g., genome-wide, RNA, and long-read DNA and RNA sequencing, genome-wide methylation profiling, and chromatin accessibility data ) from a large number of human specimens representing pediatric conditions, including childhood cancers and congenital anomalies. All data generated under this NOFO will be re-processed and harmonized by the Gabriella Miller Kids First Pediatric Data Resource Center (Kids First DRC). The DRC is charged with maintaining a public-facing, cloud-based resource that enables researchers to search, access, aggregate, analyze, and share annotated genomic sequences, genomic variants, epigenomic, transcriptomic, and phenotypic datasets. Together , these resources promote comprehensive and cross-cutting research and collaboration within the pediatric research community.

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