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HEAL Initiative: Pain Management Effectiveness Research Network: Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with several other NIH institutes including NCATS, NIA, NIDCR, NCCIH, NIAMS, and NICHD, plans to issue a Notice of Funding Opportunity (NOFO) for large-scale, multisite clinical trials focused on pain management. These trials aim to evaluate the efficacy and effectiveness of interventions or management strategies that reduce opioid use, improve functional outcomes, and alleviate pain across various acute and chronic conditions. This initiative is a continuation of the HEAL Initiative Pain Management Effectiveness Research Network, with the goal of expanding evidence-based therapeutic options to improve pain relief for multiple types of pain-related conditions. The upcoming NOFO will use the UG3/UH3 cooperative agreement mechanism, and while applications are not currently being solicited, the notice serves to encourage investigators to begin developing collaborative proposals. Researchers with expertise in clinical trials for pain management interventions, especially those involving testing existing pharmaceuticals, repurposed drugs, or devices, are urged to prepare for submission. This effort supports advancing patient care by identifying effective pain treatments that can reduce reliance on opioids and enhance quality of life for individuals experiencing pain. The lead point of contact for this opportunity is Dr. Yolanda F. Vallejo.

General Info

NINDS and NIH institutes to fund large multisite clinical trials on opioid-reducing pain management.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Yolanda F. Vallejo PhD
+1 (555) 000-0000

Full Description

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The National Institute of Neurological Disorders and Stroke (NINDS), with the National Center for Advancing Translational Sciences (NCATS), National Institute on Aging (NIA), National Institute of Dental and Craniofacial Research (NIDCR), National Center for Complementary and Integrative Health (NCCIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the conduct of  large-scale, multisite clinical trials (CTs) that will inform clinicians about the efficacy or effectiveness of interventions or management strategies that reduce opioid use, improve functional outcomes and reduce pain across the continuum of acute to chronic pain associated with many types of diseases, conditions, or pain presenting as a disease itself. This NOFO will be a continuation of the HEAL Initiative Pain Management Effectiveness Research Network (ERN). The goal of this NOFO will be to expand the suite of evidence-based effective therapeutics to alleviate pain for multiple pain conditions to benefit patients and their families. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.  This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights into this area of performing effectiveness trials for pain management interventions are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in testing existing pharmaceutical, repurposed therapeutics and/or existing devices will be encouraged, and these investigators should also begin considering applying for this application.

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