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HUBBLE DRAFT Program Announcement (PA)

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DARPA-PA-26-10_DRAFTFederal

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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office is issuing a presolicitation notice for the HUBBLE program, which aims to develop an in-silico capability for mapping all protein-protein interactions. The goal is to create a comprehensive human interactome hypercatalog, demonstrating its utility by identifying novel diagnostic and therapeutic targets for conditions such as traumatic brain injury. The program is structured in two phases, with Phase 1 lasting 12 months and Phase 2 lasting 18 months. Key deliverables include the development of PPI fingerprinting capabilities, the capture of a minimal interactome for mild traumatic brain injury, and the generation of a massive PPI hypercatalog benchmarked against DARPA-provided experimental datasets. Awards will be issued as Other Transactions for Research under 10 U.S.C. 4021, meaning they are not subject to the Federal Acquisition Regulation or the Defense Federal Acquisition Regulations Supplement. Eligible applicants include large and small businesses, universities, research institutions, and nontraditional defense contractors. Proposers must be registered in the System for Award Management and maintain CMMC Level 1 compliance. Evaluation is based on technical comprehension, technical ability, and the reasonableness of the cost rough order of magnitude. Submissions must be made via DARPA's Broad Agency Announcement Tool, and all abstracts must remain unclassified.

General Info

DARPA HUBBLE program seeks in-silico human protein-protein interaction mapping for diagnostic and therapeutic targets.

Agency

Department Of Defense → Defense Advanced Research Projects Agcy

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Arlington, VA, USA

Set-Aside

NONE

Documents

(1)

DARPA-PA-26-10 HUBBLE Presolicitation

PDF•presolicitation

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Timeline

PhasePresolicitation
Posted

Presolicitation

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Submission deadline

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
Contacts1 person available
OfficeARLINGTON, VA, 222032114, USA
Organization / AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
Office AddressARLINGTON, VA, 222032114, USA
Contacts
Dr. Abhishek Singharoy DARPA/BTO
contact@example.gov

Full Description

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IMPORTANT DISCLAIMER



THIS IS A PRESOLICITATION NOTICE FOR INFORMATION ONLY.
The official solicitation will be issued under Notice ID: DARPA-PA-26-10.
ALL INFORMATION CONTAINED HEREIN IS DRAFT AND SUBJECT TO CHANGE.
In the event of any conflict, the published Program Announcement on SAM.gov takes precedence.


The Defense Advanced Research Projects Agency (DARPA) anticipates soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying conditions including traumatic brain injury.

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