Hypoxia Chamber Services

This is a request for information issued by NASA Johnson Space Center under solicitation number 80JSC026HY018 for Hypoxia Chamber Services, aimed at gathering capabilities from potential contractors to support research into the physiological, cognitive, and clinical effects of mild hypobaric hypoxia in support of the Artemis Program. The government has no obligation to award a contract, and responders are only required to submit a capabilities statement outlining their ability to perform the described work. The core objective is to execute two separate 7-day test protocols using a cross-over design with six subjects, each undergoing exposure to a low-pressure environment equivalent to 7,000 feet altitude for five continuous days following two days of baseline measurements under ambient pressure. The contractor must provide full infrastructure including a hypobaric chamber capable of sustaining precise pressure, temperature, and gas composition controls, along with operational personnel present continuously throughout each test, comprehensive medical support, and all necessary logistical arrangements such as food, water, hygiene, sleeping, and waste management for the subjects. Medical protocols include pre- and post-chamber physical exams, continuous health monitoring using standardized tools like the Lake Louise AMS scoring questionnaire, and emergency response procedures with defined termination criteria based on NASA and facility safety standards. The contractor is responsible for collecting and transmitting a detailed electronic data package upon completion of each test, using NASA-approved secure methods, including chamber pressure and environmental recordings, medical logs, cognitive and sensorimotor test results, actigraphy data, blood and urine sample records, in-chamber video, and case reports of any altitude-related illnesses such as AMS, HAPE, or HACE. All subjects must be professionally screened for eligibility, including a VO2pk minimum of 27.5 ml/kg/min, and must provide documented informed consent. If blood or saliva analysis cannot be conducted on-site, the contractor must include in their response the costs and logistics for shipping samples to Johnson Space Center for processing. The work must be performed in Houston, Texas, and any proposed pricing structure must be firm fixed price with optional interim milestone payments, the timing of which is to be defined by the responder. This sourcing initiative uses NAICS code 541715 and was posted on June 18, 2026, with a response deadline of June 30, 2026. No formal contract clauses, evaluation factors, or award requirements are currently applicable as this remains an early-stage information gathering effort.