This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on September 10, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

Illumina DRAGEN Tier 3 Throughput License and v4 Server

Closed

75N98026Q01167Federal

Submission Closed09/14/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

Federal

Digital Biomarker & Computational Modeling DevelopmentThis subcontract focuses on the development and validation of objective digital biomarkers and computational models to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves utilizing high-performance computing and AI/ML software frameworks to create algorithms for early disease detection and predictive models for disease forecasting. The project requires strict adherence to HIPAA compliance and FDA software validation standards to ensure the integrity and security of the delivered models. Performance will take place in Frederick, Maryland, with the primary objective of delivering validated digital biomarkers and predictive tools to the Department of Defense.

Defense Health Agency

POSTED

DEADLINE

TBI & Psychological Health Research Services

Defense Health Agency

POSTED

DEADLINE

Space Power and Reactor Capabilities (SPARC) - Sources Sought Notice

Solicitation # 80GRC026R0009_PS

NASA Glenn Research Center

POSTED

DEADLINE

Atomically Precise Molecules (APM)

Solicitation # DARPA-PS-26-141

The Atomically Precise Molecules (APM) program, solicitation DARPA-PS-26-141, is a 36-month initiative by the DARPA Multi X Office seeking innovative synthesis techniques for programmable precision polymers (PPPs) and nonlinear optical (NLO) materials. The program aims to develop scalable materials with strictly controlled monomer sequences and compositions, culminating in a prototype NLO material integrated into a government-provided electro-optic modulator capable of achieving greater than 1THz modulation. The effort is structured in two phases, with Phase I lasting 12 months and focusing on synthesis capabilities. Research limited to inorganic materials or incremental improvements to existing state-of-the-art practices is specifically excluded. Awards will be issued as Other Transaction for Prototype Agreements, with payments processed through the Wide Area Workflow system based on a schedule of milestones. Proposals are due by December 18, 2026, via the Broad Agency Announcement Tool and must include technical, management, and pricing volumes. Eligibility is restricted to U.S. organizations, and all performers must comply with CMMC Level 2 self-certification and NIST SP 800-171 standards for safeguarding Controlled Unclassified Information. Evaluation will be based on technical approach, relevance to the DARPA mission, budget realism, and the capability to transition the technology to military or commercial sectors.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Sole Source to L3Harris ForceX, Inc | VAMPIRE Spares

Solicitation # SPRRA2-27-R-SP05

Al DLA Aviation At Huntsville

POSTED

DEADLINE

Request for Proposal (RFP) - Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs)

Solicitation # FA240126R0003

The Space Development Agency is soliciting proposals under solicitation FA240126R0003 for the Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs) effort. This IDIQ contract, which has a ceiling of 369 million dollars, covers the detailed design, civil engineering, procurement, installation, integration, and maintenance of GEP sites at multiple globally dispersed locations. The scope of work specifically includes the delivery of communications shelters, RF antennas and electronics, optical terminals and electronics, networking equipment, and software, as well as the development of Test Ground Support Equipment and Auxiliary Development Units. The acquisition utilizes a best-value tradeoff source selection process where technical, management, and past performance factors are significantly more important than price. Proposals are due by 4:00 PM Eastern Time on November 23, 2026, and must be submitted in seven volumes via the DoD Secure Access File Exchange. The contract structure includes a base period from March 31, 2027, to March 30, 2028, with an option period extending to March 30, 2029, and an overall ordering period through September 30, 2031. Pricing is a mix of Firm-Fixed-Price for labor and materials and Cost-Reimbursable for other direct costs and travel. Key compliance requirements include adherence to CMMC Level requirements, safeguarding of covered defense information per DFARS 252.204-7012, and a minimum small business participation requirement of 5 percent for large business offerors. Contractors must also implement unique item identification based on MIL-STD-130 and follow MIL-STD-129 for shipment and storage labeling. All invoicing and payment processing will be conducted through the Wide Area WorkFlow system.

FA2401 Space Development Agency Sda

POSTED

DEADLINE

Statistical ExpertiseThis small business set-aside subcontract, titled Statistical Expertise, supports prime contractors on NIH/NHGRI projects within the Department of Health and Human Services. The scope of work involves providing advanced statistical analysis and design for clinical research protocols, specifically requiring expertise in SAS or R for statistical programming, sample size calculations, and the interpretation of trial results. Key deliverables include validated statistical outputs, final analysis reports, and Statistical Analysis Plans. The performance of this contract takes place in Bethesda and is subject to strict HIPAA compliance, necessitating a mandatory Business Associate Agreement. Interested parties should note the response deadline of November 13, 2026, and the classification under NAICS code 541715.

National Institutes Of Health Olao

POSTED

DEADLINE

Protocol Monitoring and Data Management SupportThis subcontract opportunity, titled Protocol Monitoring and Data Management Support, involves providing clinical trial protocol monitoring and research data management for prime contractors on NIH/NHGRI clinical research projects. The scope of work includes monitoring clinical research protocols, managing data services, and developing transition and startup documentation to deliver validated research datasets and monitored protocol reports. Performance will take place in Bethesda, and the project is categorized under NAICS code 541715. The contract is designated as a Total Small Business Set Aside for the National Institutes of Health under the Department of Health and Human Services. To ensure regulatory compliance, the selected provider must adhere to NIH ICO Information Security and Privacy certifications and execute a Business Associate Agreement for HIPAA compliance. Responses are due by November 13, 2026.

National Institutes Of Health Olao

POSTED

DEADLINE

Commercial Solutions Opening (CSO) for Space Domain Awareness (SDA) Solutions.

Solicitation # FA2518-25-S-C001

The United States Space Force, through the Space Acquisition and Integration Office, is executing a Commercial Solutions Opening (CSO) under solicitation FA2518-25-S-C001 to acquire innovative commercial technologies, products, and services that enhance Space Domain Awareness (SDA). The program focuses on improving the ability to detect, characterize, attribute, predict, and target activities in the space domain. This long-term mechanism remains open for five years and utilizes a multi-phase submission process consisting of an initial white paper and PowerPoint briefing, an optional pitch session, and a final full proposal package. Awards are made as FAR-based fixed-price contracts, and the government reserves the right to award some, all, or none of the proposed solutions. A primary focus of the current effort is Area of Interest (AOI) 2025_01, titled Advanced SDA Tools for Research and Analytics (ASTRA), which is a 100 percent small business set-aside. This specific AOI emphasizes research, development, and prototyping for scalable data management, modeling, and agile software prototyping, with an estimated combined funding pool of 1.5 million dollars across related AOIs and a period of performance not exceeding 12 months. Phase I submissions must be unclassified, though subsequent phases may require higher classification levels. Offerors must comply with NIST SP 800-171 and CMMC 2.0 requirements, particularly if handling Controlled Unclassified Information. Participation is restricted to U.S. entities due to national security and export control considerations.

FA2518 Ussf Spoc/saio

POSTED

DEADLINE

HYDROSPHERE, BIOSPHERE, & GEOPHYSICS (HBG) SUPPORT SERVICES II - FINAL REQUEST FOR PROPOSAL (FRFP)

Solicitation # 80GSFC27R0015

The National Aeronautics and Space Administration Goddard Space Flight Center is soliciting proposals for the Hydrosphere, Biosphere, and Geophysics (HBG) Support Services II contract, under solicitation number 80GSFC27R0015. This small business set-aside is a hybrid Indefinite Delivery Indefinite Quantity (IDIQ) contract with a five-year effective ordering period. The contract allows for the issuance of both Cost Plus Fixed Fee (CPFF) and Firm-Fixed Price (FFP) task orders to support science research and computing activities across various laboratories, including the Cryospheric Sciences, Ocean Ecology, Hydrological Sciences, Biospheric Sciences, Geodesy and Geophysics, and the Terrestrial Information Systems Laboratory. The primary objective is to develop and apply space, field-deployed, and laboratory-based technologies to address societal issues related to water resources, ecosystems, sea level change, and the Earth's magnetic and gravity fields. The scope of work encompasses scientific modeling, simulation, data assimilation, satellite instrument performance analysis, and the planning and execution of field campaigns. Performance will occur at the Goddard Space Flight Center and the contractor's facilities, with acceptance managed by the Contracting Officer or a designated representative. Award selection will be based on a tradeoff approach, prioritizing Mission Suitability as the most important factor, followed by Cost and Past Performance. Proposals must be submitted in four volumes, including a numerically scored Mission Suitability volume and a detailed Cost volume. Additionally, the contractor must adhere to strict security requirements, including the provision of a Cyber Supply Chain Risk Management plan and compliance with NDAA Section 889 regarding telecommunications and surveillance equipment.

NASA Goddard Space Flight Center

POSTED

DEADLINE

AN41--Pre-clinical Research: Behavioral Assessment

Solicitation # 36C24127Q0035

The Department of Veterans Affairs intends to award a single-source Blanket Purchase Agreement for pre-clinical research services focused on Traumatic Brain Injury and Posttraumatic Stress Disorder under the authority of FAR 13.106-1(b). The project, led by Dr. Wilder Doucette, aims to identify neural signatures and behavioral deficits associated with neurotrauma and psychological trauma to develop personalized interventions using brain stimulation and pharmacotherapy. The period of performance is five years, spanning from November 13, 2026, to November 12, 2031. Work will be split between the White River Junction VA Healthcare System and Mary Hitchcock Memorial Hospital, with approximately 75 percent of the activity occurring at the latter. Key deliverables include data sets and reports on behavioral deficits and neural activity biomarkers within six months, treatment utility reports within nine months, and a comprehensive summary of study findings within twelve months and annually thereafter. All personnel must maintain specific certifications, including CITI, Bioraft training, IACUC approval, and VA-Without Compensation research affiliate designations. The government retains unlimited rights to all deliverables and data produced under the contract. Prospective vendors must be registered in SAM and VetCert, and those claiming small business status must be verified by the Small Business Administration.

241-NETWORK Contract Office 01 (36C241)

POSTED

DEADLINE

Sources Sought: Domestically Produced Hand and Measuring Tools (ACC-DTA CSO Amend 40)

Solicitation # W912CH26S0001

The Army Contracting Command – Detroit Arsenal (ACC-DTA) Commercial Solutions Opening (CSO), solicitation W912CH-26-S-0001, serves as a rapid-acquisition gateway to transition cutting-edge commercial technologies into active defense programs. This vehicle supports a diverse customer base, including the Intelligence and Security Command (INSCOM) and six Portfolio Acquisition Executives, focusing on the development, integration, and sustainment of ground vehicle systems to enhance Army modernization and readiness. The CSO utilizes a streamlined, merit-based, multi-phased evaluation process consisting of solution briefs, presentations, and commercial solution proposals. Awards may be issued through 2028 via FAR Part 12 commercial procedures or non-FAR agreements, such as transaction agreements under 10 U.S.C. 4022 and Cooperative Agreements under 31 U.S.C. 6305. The solicitation encompasses various Areas of Interest (AoI) targeting critical capabilities, including the FALCONS prototype for long-range reconnaissance, TIGER Readiness for the Abrams Main Battle Tank engine supply chain, Counter-Unmanned Aircraft Systems (C-UAS) detection, and the Light Tactical Trailer Heavy Chassis (LTT-HC). Funding ceilings for specific prototypes, such as FALCONS, range from 24 million to 30 million dollars depending on the use of government-provided kits. Key requirements include strict adherence to the Buy American Act and Specialty Metals clauses, with a prohibition on reliance on adversarial foreign nations for critical minerals. Technical evaluations focus on mission viability, affordability, and schedule realism, while administrative requirements include SAM registration, a Unique Entity ID, and compliance with NIST SP 800-171 for handling controlled unclassified information.

W6QK Acc- Dta

POSTED

1 day ago

DEADLINE

N/A

AI Contract Overview

The National Institutes of Health Undiagnosed Diseases Program is seeking to procure an Illumina DRAGEN Server v4 and a corresponding Tier 3 500,000 Gb annual throughput license under solicitation 75N98026Q01167. This acquisition is critical to replace a legacy 2017 server that has reached end-of-support and lacks the hardware capabilities to run modern pangenome references and improved variant calling workflows. The new system is essential for the secure, high-performance secondary analysis of whole-genome, whole-exome, and transcriptome next-generation sequencing data, ensuring the program maintains NIH IT security compliance and mission-critical genomic interpretation capacity. This is a sole-source procurement under FAR 13.106-1(b)(1), identifying Illumina, Inc. as the only provider capable of meeting the proprietary FPGA-accelerated architecture requirements. The contract requires delivery and verification of the hardware and throughput access within 30 days of the award at the UDP Translational Laboratory in Rockville, Maryland. Evaluation for the award will be based on technical capability, price, and past performance, with invoicing conducted on a monthly basis.

General Info

NIH seeks Illumina DRAGEN license and v4 server for rare disease data analysis.

Agency

Department Of Health And Human Services → National Institutes Of Health Nlm

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Bethesda, MD, 20814, USA

Set-Aside

NONE

Documents

75N98026Q01167 Combined Synopsis-Solicitation for DRAGEN Server and License

rfq

High

DRAGEN Combined SOW - NIH UDP Throughput License and Server v4

sow

High

Product Description and Pricing Template

pricing-template

Low

Single Source Justification: Illumina DRAGEN Tier 3 Throughput License and v4 Server

justification-and-authorization

Low

AI Contract Breakdown

Uniform Contract Format

Timeline

1 update

PhaseClosed

PostedSep 9

Combined Synopsis

Deadline changedSep 10

Response deadline changed from Sep 11, 2026 to Sep 14, 2026.

Response DeadlineSep 14

Deadline has passed

Submission Closed

09/14/2026, 01:00:00 PM UTC

Find active opportunities like this

Start your free trial to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Nlm

Contacts2 people available

OfficeBETHESDA, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Nlm

Office AddressBETHESDA, MD, 20892, USA

Contacts

Sandra Daniels

contact@example.gov

Shirley Ruiz-Lundgren

contact@example.gov

+1 (555) 000-0000

Full Description

The NHGRI Undiagnosed Diseases Program (UDP) requires both the Illumina DRAGEN 500,000Gb annual throughput license and the Illumina DRAGEN Server v4 to maintain secure, compliant, and high performance secondary analysis of next generation sequencing (NGS) data. DRAGEN serves as an essential computational supplement when UDP’s sequencing workload exceeds CIT High Performance Computing Center allocations, enabling timely processing of whole genome, whole exome, and transcriptome datasets for patients with rare and unresolved diseases. The current DRAGEN server, procured in 2017, has reached end of support. Its CentOS 7 operating system lost vendor support and security updates on June 30, 2024, increasing operational risk. In addition, the legacy dual Intel Xeon processors, 512 Gb RAM, and first generation FPGA acceleration hardware cannot support updated DRAGEN pipelines, including pangenome references and improved germline/somatic variant calling workflows. These limitations reduce analytical accuracy, throughput, and system stability. To prevent analysis delays, maintain compliance with NIH IT security requirements, and sustain mission critical genomic interpretation capacity, the UDP must acquire both the updated throughput license and the next generation DRAGEN Server v4.