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This Sources Sought opportunity from Department Of Veterans Affairs was posted on April 2, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

J066--Maintenance agreement for BD FACSAria Fusion cell sorter | Philadelphia VAMC

Closed
36C24425Q0546Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541714
New
Federal
AJ12--Development/Production - Kidney GEC-Specific AAV Vector
Solicitation # 36C24E27Q0009
The Department of Veterans Affairs is issuing a Sources Sought notice to identify capable vendors for the development and production of a kidney glomerular endothelial cell specific adeno-associated virus AAV vector. This project, funded by a VA ORD Merit award, aims to create a homing peptide enabled vector platform to target the glomerular endothelium to treat kidney injury and disease while reducing off target transduction. The scope of work is divided into three primary tasks: the engineering and incorporation of targeting peptides into the AAV capsid, testing vector binding and internalization in kidney tissue slices, and evaluating the specificity and efficiency of the modified vector through bioluminescence imaging and in vivo biodistribution studies. Qualified contractors must possess extensive onsite resources, including BSL 2 laboratories, specialized DNA and RNA facilities, and advanced instrumentation such as the Agilent Fragment Analyzer and various qPCR platforms. Vendors must demonstrate proven success in animal and human cell vector delivery and maintain full compliance with AAALAC and FELASA health standards. The government requires quarterly reporting, weekly videoconferences, and biannual face to face meetings. All generated data will be subject to Government Purpose Rights, and contractors must adhere to strict federal records management and information security protocols. Interested parties must submit a capability statement, relevant literature, and socio economic status details under NAICS 541714 by November 4, 2026.
Rpo East (36C24E)

POSTED

about 3 hours ago

DEADLINE

in 14 days
NAICS: 541714
New
Grant
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
Solicitation # RFA-AI-28-012
The National Institute of Allergy and Infectious Diseases (NIAID) has issued solicitation RFA-AI-28-012 to establish a consortium of Translational Centers Using Microphysiological Systems for Infectious Diseases (TCMID). The primary objective is to refine and validate human tissue models using Microphysiological Systems (MPS) to a level consistent with regulatory qualifications, thereby promoting their adoption by product developers and reducing reliance on laboratory animals. This initiative aligns with NIH and FDA guidance on New Approach Methodologies (NAMs) to accelerate the development of safer medical interventions by capturing human variability and patient-specific characteristics. The program is structured around an Administrative Core, a Qualification Core, and Scientific Cores, with a heavy emphasis on technical readiness, reproducibility, and regulatory acceptance. Key deliverables include the validation of assays for specific endpoints and the submission of regulatory packages. Applicants must be domestic entities, as foreign organizations and foreign subawards are strictly prohibited. Required personnel must possess deep expertise in infectious diseases, MPS platforms, bioinformatics, and FDA submission processes. Applications are due by January 29, 2027, and must be submitted via the NIH ASSIST system or approved institutional system-to-system solutions. Evaluation is based on an overall impact score considering the project's significance, the suitability of the investigators, and the quality of the institutional environment. Mandatory application components include a Data Management and Sharing Plan and a Benchmarks and Timeline PDF not exceeding six pages. Awardees must also adhere to strict cybersecurity incident reporting guidelines, notifying HHS within 48 hours of any discovery.
National Institutes Of Health

POSTED

1 day ago

DEADLINE

in 3 months
NAICS: 541714
New
Grant
Immune Tolerance Network (UM1 Clinical Trial Required)
Solicitation # RFA-AI-28-005
The National Institutes of Health, under the Department of Health and Human Services, is seeking applications through solicitation RFA-AI-28-005 to continue the Immune Tolerance Network (ITN). This cooperative agreement aims to develop tolerogenic therapies for immune-mediated disorders, specifically focusing on autoimmune diseases, allergic diseases and asthma, and the immune-mediated consequences of transplantation. The network operates through four integrated functional areas: Leadership, Clinical Operations, Core Laboratory, and Bioinformatics. Its primary objectives include designing and conducting clinical trials, performing integrated mechanistic studies, and sharing research results. Eligible applicants include small businesses and other for-profit organizations, though non-domestic entities are ineligible. Applications are evaluated based on scientific and technical merit, with a primary focus on significance and the likelihood of exerting a sustained influence on the research field. Key requirements include maintaining active registrations in SAM.gov, eRA Commons, and Grants.gov, as well as adhering to strict cybersecurity incident reporting and human subject protection protocols. The project requires a minimum effort of 3.6 person months per year for the PD/PI and mandates participation in a kick-off meeting in Bethesda, Maryland, and bi-annual steering meetings. Applications must follow specific page limits for the research strategy subsections and include detailed plans for clinical trial implementation, data management, and biorepository services.
National Institutes Of Health

POSTED

1 day ago

DEADLINE

in 3 months
NAICS: 541714
New
Federal
Pre-Award Synopsis Texas Shield
Solicitation # DARPA-SN-27-07
The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), intends to enter into an agreement with The University of Texas System consortium of universities for the Texas Shield Program. This integrated research initiative, identified by solicitation number DARPA-SN-27-07 and NAICS code 541714, focuses on developing autonomous and semi-autonomous medical technologies and scalable solutions for critical medical consumables. The primary goal is to support lifesaving medical care in contested, austere, and resource-limited environments. Key technical areas of focus include autonomous medical and robotic surgical systems, casualty evacuation, artificial-blood and supply innovation, AI-enabled clinical decision support, and mass-casualty science and simulation. This notice is a pre-award synopsis and is not a request for proposals or a competitive solicitation. Interested entities are invited to submit information by November 15, 2026, to TexasShieldxBTO@darpa.mil detailing their technical expertise, integrated research infrastructure, clinical-validation capabilities, and multi-institutional coordination capacity. Additionally, respondents must describe their consortium organizational structure, commercialization capabilities, facility clearance levels, and their ability to handle Controlled Unclassified Information. The government will not reimburse any costs associated with the preparation or submission of information in response to this notice.
Defense Advanced Research Projects Agcy

POSTED

5 days ago

DEADLINE

in 25 days
NAICS: 541714
New
Federal
Q--AMPLICON SEQUENCING SERVICES
Solicitation # 140G0226Q0047
Solicitation 140G0226Q0047 is a firm-fixed-price request for a Blanket Purchase Agreement (BPA) to provide next generation amplicon sequencing services for the USGS Upper Midwest Water Science Center’s Michigan Bacteriological Research Laboratory. The scope of work includes providing all equipment, labor, travel, and materials necessary to support research on bacterial pathogens, harmful algal blooms, microbial ecology, antibiotic resistance, and microbial source tracking. Key technical requirements include the use of Illumina MiSeq or AVITI sequencing technologies and the potential for library preparation for 16S V4 amplicon sequencing. The BPA has a total not-to-exceed value of 250,000 dollars with an estimated period of performance from September 17, 2026, to September 16, 2031. The award process prioritizes non-priced factors significantly over cost, focusing on the offeror's qualifications and technical performance. Evaluation criteria include a detailed listing of on-site equipment and calibration dates, personnel experience, internal quality assurance procedures, and a technical narrative not exceeding two pages. Performance will be executed in Lansing, Michigan, with delivery terms set as FOB Destination. Administrative requirements include electronic invoicing via the Internet Payment Platform and compliance with various federal regulations, including the Buy American Act and specific security prohibitions regarding telecommunications equipment. Proposals must be submitted to the USGS OAG Denver Acquisition Branch by September 11, 2026.
Ofc Of Acquisition Grants-Denver

POSTED

5 days ago

DEADLINE

in 2 days

General Info

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Department of Veterans Affairs Philadelphia VA Medical Center 3900 Woodland Ave, Philadelphia, PA, 19104-4551, USA

Set-Aside

NONE

Documents

1

36C24425Q0546.docx

DOCX

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Timeline

PhaseClosed
Posted

Sources Sought

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Veterans Affairs → 244-NETWORK Contract Office 4 (36C244)
Contacts1 person available
OfficePITTSBURGH, PA, 15215, USA
Office AddressPITTSBURGH, PA, 15215, USA
Contacts
Yazmin AlvarezContract Specialist

Full Description

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This is not a solicitation but rather a Request for Information (RFI/Sources Sought) for market research purposes only. Veterans Health Affairs, Network Contracting Office 4, is issuing this Sources Sought in order to identify capable firms and obtain information for planning purposes only. Veterans Health Affairs, Network Contracting Office 4, is issuing this Sources Sought in order to identify capable firms for brand-name Histology equipment and accessories listed below. Responses shall be submitted by 12:00pm (EST) April 7th, 2025. Responses shall be submitted via email to yazmin.alvarez@va.gov. All Service-Disabled Veteran-Owned Small Businesses (SDVOSB) and Veteran Owned Small Businesses (VOSB) firms that respond shall include proof of their Vets First Verification via Home·VetBiz Portal (va.gov). All small business firms that respond shall include proof of small business status via their Representations and Certifications in accordance with FAR 4.1102 Policy. While SDVOSB/VOSB contractors are preferred, all capable contractors are welcome to respond to this sources sought notice for market research purposes. All respondents shall include as part of their response a brief capability statement that covers the information in the following tentative statement of work, as well as answers to the below three (3) questions. All respondents shall be registered and active in SAM.gov|Home. The results of this market research will assist in the development of (1) the requirement, and (2) the acquisition approach (e.g., socioeconomic set-aside, full and open competition, etc.). VA assumes no responsibility for any costs incurred associated with the preparation of responses. Suggested NAICS: 541714 (Research and Development in Biotechnology (except Nanobiotechnology) Suggested PSC: J066 (Maintenance, Repair, and Rebuilding of Equipment Instruments and Laboratory Equipment) Open to suggestions from industry as to a more proper NAICS and/or PSC, as well as any potential GSA/FSS Schedule SIN categories. In addition to the information requested above, please include answers to the below 3 questions as part of your response to this Sources Sought: 1. Identify any other companies owned (wholly or in-part) by the owners of this business who provide goods or services under the same or a related NAICS codes. 2. Identify any other companies owned (wholly or in-part) by the owners of this business who provide goods or services that are registered under the same or a related NAICS code with the Center for Veterans Enterprise (CVE); Provide the certification type (SDVOSB/VOSB), Federal Identification Number, and state of incorporation for each. 3. Do you plan on responding to a solicitation for this requirement with a Joint Venture utilizing multiple owned companies as majority or non-majority owner? Yes ___No ___ If yes, please identify which companies are considering a Joint Venture and the ownership of each company. PERFORMANCE WORK STATEMENT (PWS) GENERAL: The Corporal Michael J. Crescenz VA Medical Center (CMCVAMC) is issuing this Performance Work Statement to outline the requirements for a comprehensive service plan for the BD FACSAria Fusion (model #656700-23) flow cytometer and cell sorter. This advanced equipment plays an indispensable role in our research initiatives, supporting a variety of laboratory-based and translational research projects funded by various agencies, including the Biomedical Laboratory Research and Development (BLR&D), Clinical Science Research and Development (CSR&D), Rehabilitation Research and Development (RR&D), National Institutes of Health (NIH), and the Department of Defense (DoD). The BD FACSAria Fusion system was acquired in fiscal year 2017; however, its original 5-year warranty expired in March 2023. To maintain the equipment s performance and reliability, a new service plan is critically needed. SCOPE OF SERVICE: The contractor shall provide a detailed service plan for the BD FACSAria Fusion 4-laser system, along with one dedicated computer workstation. The service plan shall cover all aspects, including labor costs, travel expenses, and replacement parts for a total of four years comprising one base year and three additional option years. Key components of the service plan will include, but are not limited to, the following: Preventive Maintenance: Regular inspections and servicing. Software Updates: Ensuring the system runs the latest compatible software versions. Service Visits: Unlimited on-site visits to address any arising issues. Telephone Support: Ongoing remote assistance and troubleshooting. Emergency On-Site Service: Rapid response for critical issues requiring immediate attention. OBJECTIVES: The primary objective of this PWS is to ensure that the BD FACSAria Fusion flow cytometer and cell sorter operate at peak efficiency and reliability. This will minimize equipment downtime and support the continuous research activities conducted at CMCVAMC, thereby sustaining the momentum of crucial projects and research outcomes. WORK TASKS & DELIVERABLES: PREVENTATIVE MAINTENANCE INSPECTIONS: The contractor shall carry out a total of two thorough preventive maintenance (PM) inspections per 12-month period. Each PM inspection will include the utilization of two specialized PM kits to ensure comprehensive checking and servicing of the system. Following each PM inspection, the contractor will provide a detailed report outlining the inspection findings, any identified issues, and the corrective actions undertaken to resolve them. These reports will serve both as documentation of compliance and as a resource for ongoing equipment management. SOFTWARE REVISIONS: The contractor shall handle software revisions and updates during the entire duration of the agreement. It is imperative that the contractor ensures that the BD FACSAria Fusion system is consistently running on the latest software version that is compatible with the hardware infrastructure. This includes not just applying updates, but also verifying the successful integration of these updates to enhance system performance. SERVICE VISITS & TELEPHONE SUPPORT: The contractor will be responsible for providing an unlimited number of on-site service visits to address any technological challenges or operational issues affecting the BD FACSAria Fusion system. In addition to on-site assistance, the contractor will also offer unlimited telephone support, enabling quick troubleshooting and resolution of issues remotely, thereby reducing the need for physical visits whenever possible. EMERGENCY ON-SITE SERVICE: - The contractor must guarantee a swift response for emergency on-site services within a predetermined timeline specified in the contract. Each emergency service visit will require the contractor to document the issue addressed and the corrective measures implemented in a detailed report, contributing to the overall maintenance log for the equipment. PLACE OF PERFORMANCE: All services required under this contract shall be performed at the Corporal Michael J. Crescenz VA Medical Center Research Service, located in Building 21, Philadelphia, PA. The contractor will be granted access to the necessary facilities and equipment required for the execution of the service plan. Performance Objectives Two preventive maintenance inspections per 12-month period All Software and patch revisions during the period of agreement under OEM specifications at no cost. Service visits and telephone support as needed during the agreement period. A detailed report of all activities performed on the FACS ARIA FUSION will be provided each time a Preventative maintenance or Emergency service is executed. Services will be executed during the hours of 8:00 am and 5:00 pm Monday thru Friday. Response by contractor to Emergency or on-site services must be guaranteed within 48 hours of request. Unlimited telephone support will be provided at no additional cost to users Monday thru Friday from 8:00 am to 5:00 pm. Parts (except consumables) will be included in this service contract at no additional charge to the government. All necessary FSE labor and travel for PMs are repairs are included. The contractor will provide priority scheduling for service calls and access to spare parts inventory when available. Calibrations, alignments, lubrication and part replacement will be performed as deemed necessary by Contractor to maintain the device s operation substantially in accordance with the published technical specifications for the device. CONTRACTOR QUALIFICATIONS: The contractor must meet the following qualifications to be considered eligible for this service plan: Proven experience in servicing BD FACSAria Fusion flow cytometers and related cell sorting technologies. Access to authentic BD parts and authorized software updates necessary for repairs and maintenance. Technicians who are trained and certified, equipped with the skills required for executing preventive maintenance, conducting repairs, and applying software updates on the BD FACSAria Fusion system. BD Bioscience Instrument, the Manufacturer of the FACS ARIA FUSION is fully qualified to service this high-Tech device. All field Service Engineers (FSE) performing under this contract must be experienced in the service and repair of all BD equipment in particularly to the FACS ARIA FUSION 4 LASER SYSTEMS. All FSEs must have original manufacturers (OEM) training to include all OEM publications and diagnostic tools tailored to this device and any software deemed necessary to upgrade this device during PMs. CLINs STRUCTURE: ITEM NUMBER DESCRIPTION POP BEGIN POP END QUANTITY UNIT OF MEASURE 0001 FACSAria Fusion 4 Laser System Technical Support IAW Performance Work Statement (PWS) 04/18/2025 04/17/2026 1 JB 1001 FACSAria Fusion 4 Laser System Technical Support IAW Performance Work Statement (PWS) 04/18/2026 04/17/2027 1 JB 2001 FACSAria Fusion 4 Laser System Technical Support IAW Performance Work Statement (PWS) 04/18/2027 04/17/2028 1 JB 3001 FACSAria Fusion 4 Laser System Technical Support IAW Performance Work Statement (PWS) 04/18/2028 04/17/2029 1 JB

More opportunities from Department Of Veterans Affairs → 244-NETWORK Contract Office 4 (36C244)

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NAICS: 236220
New
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Solicitation # 36C24426B0015
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Z1DA--NRM| 460-26-007 Electrical Distribution Inspection Repairs | NCO 4 Construction East (VA-26-00057558)
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The Department of Veterans Affairs Network Contracting Office 4 has issued a Request for Information for planning and market research purposes regarding electrical distribution inspection repairs at the Wilmington, Delaware VA Medical Center. This is not a request for proposal, and the government is not obligated to award a contract based on this notice. The project involves repairing all failures identified in the facility's electrical inspection and testing report, specifically focusing on the review and validation of results, the procurement and installation of circuit breakers and racking mechanisms, and the repair of old equipment to be used as future spares. All work must adhere to VA requirements, NETA test standards, and applicable federal, state, and local codes, with a total performance period of 365 days from the Notice to Proceed. The estimated magnitude of construction is between 25,000.00 and 100,000.00. This opportunity is designated as a set-aside for Service-Disabled Veteran-Owned Small Businesses under NAICS code 236220 for Commercial and Institutional Building Construction. Interested contractors must submit a statement of interest, capability statement, pricing for similar past projects, and company identification details, including their UEI number and intended contracting role, to the designated point of contact by October 30, 2026, at 4:00 PM EST. Submissions must be electronic, as hard copies will not be accepted.
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