Light Obscuration Instrument

The Bioprocess Measurements Group at NIST in Gaithersburg, Maryland is seeking a modernized flow imaging instrument with integrated light obscuration capabilities to replace two obsolete and unsupported systems currently in use. These outdated instruments hinder the group’s ability to generate data that is comparable with industry standards, limiting collaboration and compliance with regulatory requirements for characterizing challenging biologically or synthetically derived particles in drug products. The current industry reliance on flow imaging microscopy and light obscuration as compendial methods underscores the urgent need for an updated system that aligns with contemporary analytical practices, ensuring accurate, consistent, and interoperable particle characterization essential for biomanufacturing quality control. The solicitation, identified by number 1333ND26QNB640309 and published on August 4, 2026, is open for responses until August 14, 2026, and falls under NAICS code 334510 for medical and diagnostic laboratory equipment manufacturing. The contract is administered by the Department of Commerce through NIST, with primary point of contact Rene D. Edwards and secondary contact Robert Singman, reachable via phone and email provided. Both the solicitation and performance location are in Gaithersburg, Maryland, 20899, and no set-aside provisions apply, making it open to all eligible respondents. The updated instrument is critical for maintaining NIST’s leadership in measurement science and ensuring its standards remain relevant and applicable to the evolving biopharmaceutical industry.