Limited Competition: Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) (P30 - Clinical Trial Not Allowed)

The Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) is a limited competition funding opportunity issued by the National Institutes of Health under PAR-27-055 to strengthen biomedical research capacity at institutions in states historically underserved by NIH funding. This initiative supports IDeA-eligible institutions in expanding their research infrastructure through COBRE-E, which focuses on growing the faculty base and establishing new research projects and core facilities in strategically important scientific areas, and sustaining these gains through COBRE-S, which aims to consolidate research cores and further develop institutional research excellence. Applications must demonstrate a clear pathway to long-term self-sufficiency and alignment with the institution’s research priorities, with clinical trials explicitly prohibited under this P30 award mechanism. The solicitation is open only to eligible organizations that have previously received COBRE funding and are positioned to advance to the expansion or sustainability phase. The opportunity is governed by standard NIH peer-review procedures, with funding decisions based solely on scientific merit. Applications must be submitted by the deadline of May 25, 2029, and institutions interested in applying should reference the official NIH Grants.gov page for detailed eligibility criteria and submission guidelines. Questions regarding the program can be directed to the designated NIH point of contact through email or phone.