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Limited Competition: The NHGRI Analysis, Visualization, and Informatics Lab-space (AnVIL) (U54 Clinical Trial Not Allowed)

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Contract Overview

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AI Contract Overview

The National Human Genome Research Institute intends to issue a Notice of Funding Opportunity for a limited competition renewal of the Analysis, Visualization, and Informatics Lab-space program. This secure, cloud-based platform allows researchers to analyze large-scale genomic datasets without local infrastructure, currently hosting over 5 petabytes of data from nearly 300,000 participants. The renewal focuses on advancing FAIR principles, enhancing scalability, and strengthening interoperability within the NIH data ecosystem while maintaining strict security and access management standards. The program will integrate emerging data types and AI-based computational tools and expand training and outreach to improve researcher proficiency with multimodal datasets. This initiative utilizes the U54 activity code and is expected to publish its NOFO in 2027. Eligible organizations will be invited to apply, and funding will be awarded based on a standard peer-review process to ensure only meritorious applications are selected.

General Info

NHGRI renews AnVIL program for scalable, secure genomic data access, analysis, and researcher training.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

518210 - Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services

Place of Performance

Not specified

Set-Aside

NONE

Documents

No documents available

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AI Contract Breakdown

Uniform Contract Format

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Timeline

PostedJun 2

forecast

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health

Contacts1 person available

OfficeUSA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health

Office AddressUSA

Contacts

Office of the Director / Office of Genomic Data Science

contact@example.gov

Full Description

The National Human Genome Research Institute (NHGRI) intends to issue a Notice of Funding Opportunity (NOFO) to support a limited competition renewal of the Analysis, Visualization, and Informatics Lab-space (AnVIL) program. AnVIL is a secure, cloud-based platform that enables researchers to access, share, and analyze large-scale genomic datasets without relying on local infrastructure. Currently, AnVIL hosts more than 5 petabytes of data from nearly 300,000 research participants, providing a robust environment for reproducible, cloud-native genomic research.

The renewed program will continue to advance AnVIL as a community resource grounded in FAIR (Findable, Accessible, Interoperable, and Reusable) principles. Key priorities include enhancing scalability; strengthening interoperability across a federated NIH data ecosystem; and maintaining rigorous security aligned with the Research Authentication Service (RAS) and NIH controlled-access data repositories and access management systems (CADR) requirements (see NOT‑OD‑25‑159). The renewal will also support integration of emerging data types and computational tools, including infrastructure for developing and running AI-based methods and complex analysis workflows.

In addition to platform development, the program will expand training and outreach to help researchers effectively use AnVIL’s multimodal datasets and reproducible analysis capabilities. By connecting secure data access, analytical tools, and workforce development, the renewed AnVIL program aims to accelerate discovery across the research lifecycle and strengthen the genomics community’s capacity for clinical and translational science.

This Notice is being provided to allow potential applicants sufficient time to develop responsive applications. The NOFO is expected to be published in 2027 with an anticipated application due date in 2027. This NOFO will utilize the U54 activity code.

This is a Forecast for a limited competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.