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This Special Notice opportunity from Department Of Health And Human Services was posted on November 13, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

MAKING OBSTETRIC CARE SMART (MOCS)

Closed
ARPA-H-SN-26-141Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 54171
New
Federal
2026 Distributed Wind Turbine Competitiveness Improvement Project
Solicitation # RFX-2026-10008
The 2026 Distributed Wind Turbine Competitiveness Improvement Project, solicitation RFX-2026-10008, is a best-value solicitation issued by the Department of Energy through the National Laboratory of the Rockies. This project seeks firm fixed-price subcontracts with price participation to enhance the competitiveness of U.S. distributed wind turbines and power electronics. The scope is divided into thirteen topic areas covering prototype design, manufacture, installation, testing, component innovation, system optimization, certification, power electronics development, manufacturing process innovation, technology commercialization, and field validation. The primary objective is to reduce the Levelized Cost of Energy (LCOE) and expand domestic manufacturing. The anticipated period of performance is generally twenty-one months per topic area, though field validation may extend up to sixty months. Funding varies by topic, with maximums ranging from 200,000 dollars for design and commercialization to 800,000 dollars for prototype manufacture, type certification, power electronics pre-testing, and manufacturing process innovation. Offerors may propose for a single topic or a phased approach involving up to three areas. Evaluation is based on a 105-point scale considering technical merit, project team qualifications, and programmatic diversity regarding manufacturer size, geography, and system configuration. Proposals must be submitted as assembled PDFs to Kyndall Jackson by November 16, 2026, at 12:00 PM MST. Requirements include a technical proposal with strict page limits, a price/cost proposal, and specific eligibility and technical specification attachments. Subcontractors must be U.S. companies performing work within the United States and must adhere to safety and certification standards such as ANSI/ACP 101-1-2021. Contract administration includes electronic invoicing through the NLR Accounts Payable office and strict adherence to DOE public affairs and classified information directives.
Llc - DOE Contractor Alliance For Energy Innovation

POSTED

4 days ago

DEADLINE

in 3 days
NAICS: 54171
Federal
Commercial Solutions Opening for Joint All-Domain Command and Control (JADC2)
Solicitation # FA8612-21-S-C001
The Joint All-Domain Command and Control (JADC2) Commercial Solutions Opening (CSO), solicitation FA8612-21-S-C001, is a streamlined acquisition framework managed by the Air Force Architecture and Integration Directorate (AFLCMC/XA). Its primary objective is to leverage innovative commercial and defense technologies to reduce kill chain and Observe, Orient, Decide and Act (OODA) timelines by ensuring the right information reaches the right decision maker efficiently. The CSO serves as an umbrella solicitation that does not accept direct proposals but instead issues specific Calls for various Areas of Interest (AoIs). These Calls focus on several Technology Focus Areas, including digital architecture, sensor integration, data management, secure processing, connectivity, applications, and effects integration. The acquisition process is highly flexible, utilizing a hybrid approach of Closed Calls (one-step or two-step) and Open Period Calls. Most efforts follow a two-step process where white papers are first evaluated as Selectable or Not Selectable based on technical merit, innovation, and price reasonableness; only selected offerors then receive a Request for Proposal (RFP). Depending on the specific Call, the government may award FAR Part 12 contracts, procurements for experimental purposes under 10 U.S.C. 4023, or Other Transaction Agreements (OTAs) under 10 U.S.C. 4021. All resulting agreements are fixed-price and may include provisions for follow-on production contracts. Recent activities under this CSO include Call 001 for DevSecOps and multi-level security networks, Call 002 for virtualized SD-WAN solutions, and Call 003 for Software Programmable Open Mission Systems Compliant Multi-Function Processors. The program emphasizes open architecture standards, such as SOSA, and requires proposed technologies to generally meet a Technology Readiness Level (TRL) of three or higher. The solicitation is open to traditional and nontraditional defense contractors, small businesses, and research institutions, provided they meet necessary security clearances and registration requirements in SAM and SPRS.
FA8612 Aflcmc C3BM C3

POSTED

12 days ago

DEADLINE

in 12 months
NAICS: 54171
Federal
N0016425SC001 CSO
Solicitation # N0016425SC001
The Naval Surface Warfare Center, Crane Division (NSWC Crane) is utilizing a Commercial Solutions Opening (CSO) under solicitation N0016425SC001 to rapidly acquire innovative commercial products and services. The objective is to identify and integrate advanced technologies across three primary mission areas: Expeditionary Warfare, Strategic Missions, and Electromagnetic Warfare. This competitive, three-phased process consists of an initial Solution Brief, a Pitch session, and a final written proposal. Awards are issued on a fixed-price basis and may take the form of FAR-based contracts, Purchase Orders, Bailment Agreements, or prototype Other Transaction (OT) agreements. Specific Areas of Interest (AOIs) have been released for various high-priority projects, including the Miniature Aiming System (MAS) Machine Gun Optic, the Small Modular Optic and Laser Designator (SMOLDr), the Hypervelocity Improved Capability Assault Rifle (HICAR), the Modular Kinetic Lethal Drone (MKLD), and the Flyweight Assault Machine Gun (FAMG). These projects focus on enhancing lethality and readiness through advancements in electro-optic systems, man-portable belt-fed weapons, and autonomous loitering munitions. Successful completion of a prototype OT project, validated through milestones such as User Evaluation and Operational Testing, may lead to a follow-on production contract without further competition.
Nswc Crane

POSTED

5 months ago

DEADLINE

in over 1 year
NAICS: 54171
Federal
Defense Innovation Unit Commercial Solutions Opening
Solicitation # HQ0845-20-S-C001
The Defense Innovation Unit (DIU) is utilizing a streamlined Commercial Solutions Opening (CSO) to award funding agreements to traditional and nontraditional defense contractors for prototype projects. These projects aim to enhance military effectiveness and national security through the adoption of innovative commercial technologies, processes, or business practices. Awards are executed as Other Transaction Agreements (OTAs) under the authority of 10 U.S.C. 2371b, allowing for an iterative prototyping process that includes concept demonstrations, pilots, and agile development. The procurement is administered by the DIU in coordination with the Washington Headquarters Service and the Army Contracting Command. The competitive process consists of three distinct phases: the submission of a Solution Brief in response to specific Areas of Interest (AOI), an invitation to a pitch session to demonstrate technical and business viability, and the submission of a full written proposal. Evaluation is based on the merit of the proposed concept, specifically focusing on relevance to the AOI, innovation, uniqueness, and technical feasibility. Eligible respondents must be registered in the System for Award Management (SAM), possess a DUNS number, and be determined responsible by the Agreements Officer. While the government requires a total price proposal for the prototype project, the Agreements Officer will negotiate final terms, conditions, and payments directly with the selected company, including the potential consideration of company-proposed service or user license agreements.
Defense Innovation Unit

POSTED

7 months ago

DEADLINE

N/A
NAICS: 54171
Federal
Washington Headquarters Services (WHS) Commercial Solutions Opening (CSO)
Solicitation # HQ0034259WHSCSO
The Washington Headquarters Services Acquisition Directorate, through its Emerging Capabilities and Defense Prototyping Division, is utilizing a Commercial Solutions Opening to accelerate the attainment of defense capabilities. This five-year solicitation seeks innovative commercial products, services, and technologies, including concept demonstrations, pilots, and agile development activities. The program operates by publishing specific Areas of Interest that solicit solutions from commercial entities, with a particular emphasis on engaging non-traditional defense contractors and small businesses. Awards are issued as Other Transaction agreements under authorities including 10 U.S.C. Section 3458 and 4022, meaning they are not governed by the Federal Acquisition Regulation, though they remain subject to federal law and specific non-negotiable terms. The competitive process is multi-phased, requiring the submission of unclassified solution briefs, pitches, and prototype proposals. Solution briefs are evaluated based on the solution concept and business viability, including the company's go-to-market strategy and fundraising history. Successful projects are determined by the Agreements Officer based on the achievement of key technical goals or success metrics. To be eligible for an award, companies must maintain active registration in the System for Award Management and the Wide Area Work Flow for invoicing. The government protects confidential commercial information and trade secrets under applicable federal laws and executive orders, while requiring offerors to identify any intellectual property restrictions associated with their proposed solutions.
Washington Headquarters Services

POSTED

8 months ago

DEADLINE

in over 3 years
NAICS: 54171
Federal
LPS Qubit Collaboratory (LQC)
Solicitation # W911NF21S0009
The LPS Qubit Collaboratory (LQC), a partnership between the U.S. Army Research Office and the NSA's Laboratory for Physical Sciences, is soliciting research proposals to advance disruptive fundamental research in quantum information science and technology. The program focuses on qubit development for quantum computing and sensing, aiming to solve long-term challenges in qubit device physics, such as material selection, gate fidelity, and the operation of superconducting qubits. The LQC operates as a center without walls, fostering collaborative partnerships between academia, industry, FFRDCs, and government laboratories to build a future quantum workforce and create pathways for technology transition. Proposals are accepted in three categories: Incubator opportunities for single investigators or small groups to develop concepts; Collaboratory proposals for multi-sector teams to pursue proof-of-concept experiments over one to three years; and QuaCR Research Fellowships for U.S. citizen graduate and postdoctoral researchers. Eligible applicants include domestic and foreign institutions of higher education, nonprofits, and for-profit businesses. Awards are evaluated based on scientific and technical merit, potential contribution to quantum computing feasibility, investigator qualifications, and cost reasonableness. The current response deadline for submissions is April 30, 2027.
W6QK Acc-Apg Durham

POSTED

8 months ago

DEADLINE

in 6 months
NAICS: 54171
Federal
AFRL/RX Functional Materials Open BAA
Solicitation # FA8650-22-S-5002
The Air Force Research Laboratory Materials and Manufacturing Directorate is soliciting white papers and full proposals under Broad Agency Announcement FA8650-22-S-5002 to advance functional materials technologies. The program focuses on the full maturity spectrum from scientific discovery through transition into components and systems, with specific interests in Photonic Materials, including Optical Materials and Processes and Hardened Materials and Processing. The objective is to exploit innovative materials from academia, defense, and commercial sectors to enhance warfighting capabilities, specifically improving size, weight, and power characteristics. Total program funding is approximately 500 million dollars, with individual contract awards capped at 75 million dollars. The solicitation utilizes a two-step process requiring an initial white paper followed by a technical and cost proposal for selected offerors. Awards are anticipated to be Cost Plus Fixed Fee contracts with periods of performance ranging from 12 to 72 months. Evaluation is based on peer or scientific review, agency importance, and funding availability, with technical merit as the primary priority. Due to the sensitive nature of the research, strict security requirements are in place, including a Security Risk Review to mitigate foreign influence, adherence to the AFRL Wright Research Site Security Requirements, and potential Secret level safeguarding as specified in DD Form 254. Deliverables include scientific and technical reports, proof-of-concepts, and prototype hardware or software.
FA8650 USAF Afmc Afrl Pzl Afrl/pzl

POSTED

9 months ago

DEADLINE

in almost 2 years
NAICS: 54171
Federal
NEEDIPEDIA BROAD AGENCY ANNOUNCEMENT - BAA
Solicitation # HHM402-23-S-0001
The NeedipeDIA Broad Agency Announcement (BAA), solicitation number HHM402-23-S-0001, is an agency-wide initiative by the Defense Intelligence Agency (DIA) to solicit innovative ideas and technological capabilities from a diverse range of sources, including large businesses, small businesses, academic institutions, and independent consultants. The program utilizes the NeedipeDIA system, which employs classified and unclassified web portals to present specific mission needs to the public. The objective is to maximize operating efficiency and effectiveness in support of national and international mission requirements through research, study, and experimentation. This BAA is a follow-on to HHM402-19-S-0001 and remains open for submissions from December 29, 2023, through December 28, 2028. Interested parties must first submit a two-page white paper, accompanied by a mandatory coversheet, addressing a specific NeedipeDIA Need Area. Proposals are evaluated on their own merit based on overall innovation, relevance to the DIA mission, and the realism of the proposed cost. The procurement process allows for rapid contracting solutions in accordance with Federal Acquisition Regulations and may utilize Other Transaction Authority under 10 USC 4021. All proposers must be registered in the System for Award Management (SAM) and adhere to strict guidelines regarding Organizational Conflicts of Interest (OCI) and the handling of Controlled Unclassified Information (CUI). Final awards are administered by the Virginia Contracting Activity, with payments processed electronically via Wide Area Work Flow (WAWF).
Virginia Contracting Activity

POSTED

11 months ago

DEADLINE

in about 2 years

General Info

NAICS

54171

Place of Performance

Washington, DC, 20005, USA

Set-Aside

NONE

Documents

1
PDF, Low priority3 pages · special-notice
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Timeline

PhaseClosed
Posted

special-notice

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA

Full Description

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This Special Notice (SN) provides information about the ARPA-H MOCS Program Proposers’ Day (PD) on December 11th, 2025. ARPA-H published an Innovative Solutions Opening (ISO) for the GIVE program on November 13th, 2025. For additional PD details and registration information see the attached Special Notice
(ARPA-H-SN-26-141).


The MOCS ISO (ARPA-H-SOL-26-143) is posted on SAM.GOV and additional information about the program can be found on the ARPA-H website: https://arpa-h.gov/explore-funding/programs/mocs


It is anticipated that creation of a quality proposal to meet all criteria will require combining technologies and/or companies, which can be time consuming and challenging.  It is recommended that proposers and potential collaborators (clinical partners, malpractice attorneys, regulatory consultants, CROs, etc.) submit a teaming profile as soon as possible to form the best teams possible. Teaming profiles can be submitted at solutions.arpa-h.gov/teaming.


More opportunities from Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Same awarding agency

NAICS: 541714
New
Federal
Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)
Solicitation # ARPA-H-SOL-26-164
The Advanced Research Projects Agency for Health (ARPA-H) is soliciting proposals for the Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) program under solicitation ARPA-H-SOL-26-164. This five-year initiative aims to create a reusable blueprint for future adaptive seamless platform trials through the integration of three technical areas: a Phaseless Design Engine, Continuous Inference, and Agentic Operations. The program is divided into two stages, with Stage I focusing on capability buildout, FDA engagement, and the onboarding of at least three intervention arms over 24 months, followed by a 36-month Stage II dedicated to validation and deployment. A critical go/no-go milestone is obtaining FDA authorization for the platform Master Protocol IND and at least one investigational arm by the end of Stage I. The government intends to make multiple awards via Other Transaction Agreements to proposers offering the most advantageous solutions based on innovation, feasibility, and technical merit at reasonable prices. Eligible entities must possess a Unique Entity Identifier and active SAM registration. Proposals are submitted in a phased approach, beginning with a Solution Summary and potentially progressing to a Solution Pitch package. Performance will be measured by the successful integration of the three technical areas and the achievement of specific program metrics. All work must adhere to ICH E6(R3) Good Clinical Practice and strict regulatory standards to ensure inspection readiness and participant safety.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 12 hours ago

DEADLINE

in 17 days
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NAICS: 541715
New
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Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)
Solicitation # ARPA-H-SOL-26-163
The Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) program, issued by the Advanced Research Projects Agency for Health (ARPA-H) Proactive Health Office under solicitation ARPA-H-SOL-26-163, seeks innovative solutions to identify and act upon autism trajectories across the lifespan. The program focuses on the nonlinear interactions of genetic, biological, behavioral, and environmental factors to move toward personalized care. The scope is divided into four Technical Areas: TA1 focuses on multi-factor analysis and trajectory identification; TA2 involves population-scale modeling and data integration; TA3 centers on precision intervention and trajectory testing; and TA4 targets technologies for communication, quality of life, and embedded assessment. Awards will be made using Other Transaction (OT) instruments through a two-stage submission process consisting of a Solution Summary and a Full Proposal. Technical performance is monitored via a milestone-based system with evaluation gates at Month 10, Month 22, and a final evaluation at Month 46. Key requirements include strict adherence to HIPAA Privacy Rule de-identification standards, the implementation of independent data safety monitoring boards for harm surveillance, and the disclosure of any organizational conflicts of interest. Submissions must follow specific formatting guidelines, including the use of Avenir Next LT Pro font for summaries and a multi-volume structure for full proposals, with a response deadline of December 2, 2026.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

5 days ago

DEADLINE

in 19 days
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NAICS: 541714
Federal
ARPA-H Emerging Health Innovators (EHI) Initiative
Solicitation # ARPA-H-SOL-26-150
The Advanced Research Projects Agency for Health (ARPA-H) Emerging Health Innovators (EHI) initiative, solicitation ARPA-H-SOL-26-150, seeks to identify and engage early-career investigators to develop cutting-edge biomedical, health, and community-engaged research. This opportunity is open to researchers from academic, nonprofit, and industry organizations, provided the Principal Investigator is within eight years of completing their first terminal degree. The initiative covers 16 specific topic areas, including AI in life sciences, brain stimulation, and human tissue platforms. Awards are issued as Other Transaction (OT) agreements, which are not subject to the Federal Acquisition Regulation (FAR). The selection process is a two-step submission involving an initial anonymized Solution Summary and a subsequent Full Proposal for selected candidates. Successful awards have a total value not to exceed 1,050,000 dollars over a three-year period, consisting of a 24-month base period capped at 700,000 dollars and an optional 12-month Director's Award period capped at 350,000 dollars. Payments are structured as fixed payments triggered by the completion of 12 discrete, measurable milestones. Full proposals are evaluated based on technical merit, innovativeness, feasibility, alignment with the ARPA-H mission to accelerate health outcomes, and price reasonableness. Administrative requirements include mandatory registration in SAM.gov and the use of the ARPA-H Solutions site for all submissions. Proposers must adhere to strict formatting templates for technical and management proposals, milestone schedules, and national policy requirements, including disclosures regarding organizational conflicts of interest and research security. Performance is monitored through a formal inspection and acceptance process where the government reviews deliverables within 14 calendar days. The tentative award start date is June 30, 2027, with full proposals due by February 10, 2027.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

23 days ago

DEADLINE

in 3 months
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NAICS: 541714
Federal
UNifying Imaging with QUantum Entanglement (UNIQUE) Innovative Solutions Opening (ISO)
Solicitation # ARPA-H-SOL-26-162
The Advanced Research Projects Agency for Health (ARPA-H) is seeking innovative solutions through the UNifying Imaging with QUantum Entanglement (UNIQUE) program, solicitation number ARPA-H-SOL-26-162. This 18-month, two-phase initiative aims to develop a new biomedical imaging paradigm by integrating anatomical, functional, and molecular data using quantum-derived observables and entangled 511 keV photon pairs. The scope is divided into two technical areas: the Imaging Core, which focuses on physical systems for generating and measuring quantum observables, and the Computational Foundation, which focuses on AI-driven reconstruction and multimodal data fusion. ARPA-H anticipates awarding multiple Other Transaction Agreements to eligible universities, non-profit organizations, and businesses. The submission process is two-staged, requiring Solution Summaries by late October 2026 and Full Proposals by December 15, 2026. Full proposals must consist of three volumes covering technical and management plans, cost proposals, and administrative requirements. Evaluation is based on technical innovation and feasibility, proposer expertise, potential to transform biomedicine, and cost reasonableness. Notably, for-profit organizations that are not small businesses under NAICS 541714 are required to provide a meaningful cost share. All participants must adhere to strict HHS regulations regarding human stem cell research and prohibitions on dangerous gain-of-function research and funding for foreign entities in countries of concern.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 2 months ago

DEADLINE

in about 1 month
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