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This Government Contract opportunity was posted on March 19, 2018. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Medicinal Chemistry Support Program for Therapeutic Development (MCSP)

Awarded
NIH-NINDS-17-01Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715
New
Federal
ARMY APPLICATIONS LABORATORY BROAD AGENCY ANNOUNCEMENT FOR DISRUPTIVE TECHNOLOGIES
Solicitation # W911NF-24-S-0008
The United States Army Futures Command, through the Army Applications Lab, has issued Broad Agency Announcement W911NF-24-S-0008 to solicit disruptive technology applications. This initiative aims to modernize the Army by leveraging civilian research, development, and innovation ecosystems to create a first-mover advantage. The program focuses on seven key priorities: Long-Range Precision Fires, Next Generation Combat Vehicles, Future Vertical Lift Platforms, the Army Network, Air and Missile Defense Capabilities, Soldier Lethality, and Contested Logistics. The effort is structured around three main lines of action: the discovery of novel capability concepts, the acceleration of technology demonstrators that provide a significant improvement over current capabilities, and the translation of these innovations into scalable Army advantages. The Army is specifically seeking advancements in Fourth Industrial Revolution technologies, including artificial intelligence, robotics, autonomy, quantum information systems, synthetic biology, and advanced power and energy systems. There is a strong emphasis on translational research and the development of dual-use solutions that serve both military needs and commercial markets. This solicitation, managed by the Army Contracting Command in Research Triangle Park, North Carolina, remains active from April 5, 2024, through April 5, 2029, with performance centered in Austin, Texas.
W6QK Acc-Apg Durham

POSTED

about 21 hours ago

DEADLINE

in over 2 years
NAICS: 541715
New
Federal
Call 03 M-DASH - Joint All Domain Persistent Adaptive Collaborative Technologies II (JADPACT II)
Solicitation # FA238426SB007
The Joint All Domain Persistent Adaptive Collaborative Technologies II (JADPACT II) project, specifically the Multi-Decision Advantage Sprint for Human-Machine Teaming (M-DASH), is a research effort led by the Air Force Research Laboratory. The program aims to develop Human-Machine Teaming concepts and AI/automation capabilities to provide Battle Managers with decision advantage within the Combined Joint All-Domain Command and Control (CJADC2) framework. The effort focuses on the Transformational Model for Decision Advantage (TM-DA) to bridge the gap between operational concepts and software design, specifically requiring solutions that address three decision services: PAE, MEF, and GBC. The M-DASH event is a two-week simulation sprint scheduled for January 25 to February 5, 2027, in Las Vegas, Nevada. The government anticipates awarding Firm Fixed Price contracts or Other Transaction agreements with a maximum value of 100,000 dollars per selected offeror, out of a total estimated program cost of 600,000 dollars. Payment is issued as a single sum upon the conclusion of the event and the successful delivery of a Technical Review Presentation Package, which must include an end-of-event presentation, a technology survey, and simulated run digital audit logs. Eligibility for award requires offerors to have a CMMC Level 1 Self assessment and undergo a rigorous Science and Technology Protection risk review for all senior and key personnel. Proposals were due by October 21, 2026, and were subject to strict page limits for both the proposal and the Statement of Work. All deliverables must be submitted electronically to a government-controlled repository, and contractors must comply with AFRL supplemental requirements regarding patent rights, CUI marking, and security risk disclosures.
FA2384 USAF Afmc Afrl Pzl Afrl Rakh

POSTED

about 21 hours ago

DEADLINE

in about 12 hours
NAICS: 541715
New
Federal
U.S. Army Contracting Command – Watervliet Arsenal (ACC-WVA) Organic Industrial Base (OIB) Modernization Commercial Solutions Opening (CSO)
Solicitation # W911PT26SC001
The U.S. Army Contracting Command – Watervliet Arsenal (ACC-WVA) has issued solicitation W911PT26SC001, a Commercial Solutions Opening (CSO) authorized under the National Defense Authorization Act for Fiscal Year 2026 and DFARS Subpart 212.70. This competitive solicitation is open until September 30, 2027, and is designed to acquire innovative commercial products, technologies, and services to modernize the Army's Organic Industrial Base. The scope focuses on integrating manufacturing resources, linking legacy analogue systems with digital systems, and expanding modeling and simulation to enhance the delivery of materiel solutions. The CSO targets both traditional and non-traditional business entities, including small businesses and foreign-owned firms, provided they maintain an active System for Award Management (SAM) profile and a Unique Entity ID. The acquisition process follows a multi-phased approach consisting of a written solution brief, an optional presentation or pitch, and a final Request for Commercial Solution Proposal (CSP). Evaluation is based on responsiveness, technical merit, uniqueness, and price reasonableness. Successful responses may result in fixed-price contracts awarded under FAR Part 12 Commercial Item Procedures. Current Areas of Interest (AoIs) include advanced cannon technology, electrical infrastructure improvements at Building 120, chromium facility conversion, automated manufacturing for minor components, automated cooling tower treatments, advanced CNC vertical turning lathes, and advanced tooling for radial forging. Performance is primarily located at Watervliet Arsenal and Benet Laboratories, with a general period of performance not to exceed 12 months unless otherwise specified.
W6QK Acc Wva

POSTED

about 21 hours ago

DEADLINE

in 11 months
NAICS: 541715
New
Federal
Atomically Precise Molecules (APM)
Solicitation # DARPA-PS-26-141
The Defense Advanced Research Projects Agency (DARPA) Multi X Office is soliciting proposals for the Atomically Precise Molecules (APM) program under solicitation DARPA-PS-26-141. The program aims to develop innovative synthesis techniques for programmable precision polymers (PPPs) and nonlinear optical (NLO) materials to overcome performance gaps in optical communications and LiDAR. The primary objective is the creation of scalable, fit-for-purpose materials, culminating in a prototype demonstration of a revolutionary NLO material integrated into a government-provided electro-optic modulator. Research focusing solely on inorganic materials or incremental improvements to the state-of-the-art is specifically excluded. This 36-month effort is structured in two technical phases, with Phase I focusing on developing PPP synthesis capabilities over the first 12 months. Awards will be issued as Other Transaction (OT) for Prototype Agreements under 10 U.S.C. 4022. Key requirements include CMMC Level 2 self-assessment compliance and adherence to a program-specific Controlled Unclassified Information (CUI) guide. Non-US organizations, FFRDCs, UARCs, and government entities are ineligible to serve as prime performers, though FFRDCs and UARCs may participate as subawardees provided they meet specific certification and conflict of interest mitigation requirements. Proposals must be submitted via the Broad Agency Announcement Tool (BAAT) by December 18, 2026. Submissions must include a technical and management volume, a price proposal with a detailed spreadsheet, a Task Description Document, and a schedule of milestones and payments. Evaluation will be based on the technical approach, relevance to the DARPA mission, budget realism, and the capability to transition the technology to military or commercial sectors. Payments are milestone-based and processed through the Wide Area Workflow (WAWF) system.
Defense Advanced Research Projects Agcy

POSTED

about 21 hours ago

DEADLINE

in about 2 months
NAICS: 541715
New
Federal
NGA - Boosting Innovative GEOINT - Science & Technology Broad Agency Announcement (BIG-ST BAA): Topic # 07 – Lidar Analysis for Surface & Environmental Reconnaissance (LASER)
Solicitation # HM047627XXXX
The Boosting Innovative GEOINT-Science and Technology (BIG-ST) Broad Agency Announcement (BAA), solicitation HM047623BAA0001, is a general solicitation by the National Geospatial-Intelligence Agency (NGA) to address hard GEOINT problems across three technical domains: Foundational GEOINT, Advanced Phenomenologies, and Analytic Technologies. The BAA operates through separate Topic Calls, with current active efforts focusing on Topic 07, Lidar Analysis for Surface and Environmental Reconnaissance (LASER). This specific project aims to automate and refine AI/ML classification algorithms for the autonomous detection of man-made surface and subsurface objects using ICESat-2 and GEDI space lidar data, progressing the technology from TRL 4 to TRL 5 or 6. The LASER project has a Phase 2 budget of 854,000 dollars for a 15-month period of performance estimated to begin on February 15, 2027. Key performance metrics include a probability of detection greater than 75 percent, a probability of error less than 25 percent, and positional accuracy within 1 meter for underwater targets and centimeter scale for above-ground targets. Deliverables include a kick-off brief, AI/ML methodology reports, a comprehensive final report, and a final software demonstration. The government may issue the award as either a procurement contract or an Other Transaction Agreement. Administrative requirements mandate that proposals follow a strict four-volume template, including technical, cost, and security volumes. Security is a critical component, with requirements ranging from unclassified CUI handling to Top Secret/SCI clearances and polygraph testing depending on the work performed. Contractors must comply with DFARS 252.204-7012 for cybersecurity and utilize the Invoice Processing Platform for electronic payments. Evaluation is based on a multi-step process consisting of a conformance review and a scientific/technical review, with awards granted to the most advantageous proposals.
Attn: Ms S84 - Ocs

POSTED

about 21 hours ago

DEADLINE

in 2 months

AI Contract Overview

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The Medicinal Chemistry Support Program for Therapeutic Development is an ID/IQ contract awarded to provide turn-key medicinal chemistry operations for NINDS, the Blueprint Neurotherapeutics Network, and other NIH Institutes and Centers. The contract spans a ten-year ordering period from March 16, 2018, through March 15, 2028, with a total funding ceiling ranging from a minimum of 17,186 dollars to a maximum of 39,500,000 dollars. AMRI was awarded an initial task order for 17,186 dollars covering the first year of performance, specifically focusing on tech transfer, storage, handling, distribution, access training, and IT security for an existing compound repository. This task order includes nine additional 12-month options to extend the term through March 2028. Further task orders for medicinal chemistry support studies will be issued via a request for proposals process on an as-needed basis, typically as cost-reimbursement, completion-type agreements with variable performance periods.

General Info

Agency

N/A

Contract Value

$39,500,000

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Award Issued Date

Documents

0

No documents available

Documents will appear here when they are available.

AI Contract Breakdown

Uniform Contract Format

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Timeline

4 updates
PhaseAwarded
Posted

Presolicitation

Notice updated

Response deadline added: Sep 18, 2017. The notice description changed.

Notice updated

The notice description changed.

Notice updated

Notice details unchanged. Attachments may have changed.

Notice updated

Notice details unchanged. Attachments may have changed.

Type Changed

Presolicitation → Solicitation

Awarded

Contract was awarded

Submission Closed

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Organization & Contact Information

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AgencyN/A
Contacts1 person available
OfficeN/A
Organization / Agency
N/A
Office AddressN/A
Contacts
Annette CarterContracting Officer

Full Description

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This contract is for services to NINDS and the Blueprint Neurotherapeutics Network (BPN) to provide a full service, turn-key medicinal chemistry operation for the development of therapeutics within the mission of NINDS, BPN and other NIH Institutes and Centers (ICs). The ID/IQ contract has been awarded with a ten (10) year ordering period of March 16, 2018 through March 15, 2028. The minimum award amount is $17,186; the maximum award amount under this program is $39,500,000. AMRI has also been awarded a task order concurrent with the parent ID/IQ contract. This task order covers the first year of performance under the "Tech Transfer, Storage Handling and Distribution, Access Training and IT Security Relevant to Existing Compound Repository" component of the program. The period of performance of this task order award is March 16, 2018 through March 15, 2019 with an award amount of $17,186. The task order award also contains nine (9) additional 12-month term options which have been negotiated as follows: Option Option Period #1 - Term Extension Year 2 - March 2019 - March 2020 #2 - Term Extension Year 3 - March 2020 - March 2021 #3 - Term Extension Year 4 - March 2021 - March 2022 #4 - Term Extension Year 5 - March 2022 - March 2023 #5 - Term Extension Year 6 - March 2023 - March 2024 #6 - Term Extension Year 7 - March 2024 - March 2025 #7 - Term Extension Year 8 - March 2025 - March 2026 #8 - Term Extension Year 9 - March 2026 - March 2027 #9 - Term Extension Year 10 - March 2027 - March 2028 Task Orders for Performance Area 2, "Medicinal Chemistry Support (MCS)", for individual MCS studies will be awarded through a Task Order Request for Proposals (TORFPs) process as the need arises. It is anticipated that these task orders will be cost-reimbursement, completion-type task orders and will have variable periods of performance.

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