Mouse Irradiation & Cosmic Carcinogenesis Investigation - MICCI
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The Mouse Irradiation & Cosmic Carcinogenesis Investigation MICCI aims to evaluate how the quality of space-relevant ionizing radiation influences the risk of cancer development using an outbred mouse model, with a primary focus on carcinogenesis and relative biological effectiveness RBE measurements following low dose whole body exposures that simulate galactic cosmic radiation. The study is designed to provide critical data on the biological impacts of space radiation environments, particularly in contexts where astronauts face prolonged exposure to complex radiation fields beyond Earth’s protective magnetosphere. Additional research will examine secondary health risks including cardiovascular and degenerative diseases as well as short- and long-term neurobehavioral and cognitive impairments that may arise from such exposure. This effort is led by NASA’s Johnson Space Center and is forecasted to be posted in early 2026 under NAICS code 541715 for research and development in the physical engineering and life sciences. The primary point of contact is Jason Weeks with the project’s performance expected to occur in Boulder. The initiative seeks to inform future human spaceflight missions by quantifying health risks associated with deep space travel and will provide foundational data for risk modeling and countermeasure development. Small business participation is encouraged and queries can be directed to the designated small business specialist.
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Boulder, CO, United StatesSet-Aside
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The Space Radiation Quality Effects contract will measure the effect of Radiation Quality and Galactic Cosmic Radiation Simulation on the Risk of Carcinogenesis in an Outbred Mouse Model The priority research interest is carcinogenesis and associated RBE measurements following low dose whole body exposure to ionizing radiation relevant to the space radiation environment. Secondary priority areas i
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