This Government Contract opportunity from Department Of Health And Human Services was posted on April 22, 2020. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Multi-site, randomized, double-blind, multi-arm historical control, comparative trial of the safety and efficacy of hydroxychloroquine and the combination of hydroxychloroquine and famotidine for treatment of moderate to severe COVID-19 disease in hospita

Awarded

75A50120C00078Federal

Submission Closed04/14/2020, 12:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

New

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Specialized Thermal Data Analysis ServicesThe Specialized Thermal Data Analysis Services subcontract involves providing advanced data analysis of spectral pyrometry results for prime contractors supporting NASA Shared Services Center propulsion testing projects. The scope of work focuses on analyzing raw spectral data to ensure measurement fidelity, utilizing thermal diagnostic modeling tools to apply emissivity corrections and compensate for variables such as window fouling, plume emissions, and off-gas. The selected provider will be responsible for delivering validated temperature measurements and comprehensive data analysis reports. This opportunity falls under NAICS code 541715 and is associated with the National Aeronautics And Space Administration.

NASA Shared Services Center

POSTED

DEADLINE

Earth Science Modeling and SimulationThe Earth Science Modeling and Simulation subcontract supports prime contractors on projects for the NASA Goddard Space Flight Center. The scope of work involves performing scientific modeling, simulation, and data assimilation across several disciplines, including geodetic, geophysical, cryospheric, hydrospheric, and biospheric sciences. Key responsibilities include the development of scientific models, the execution of experiment design, and the advancement of scientific mission development. The selected provider will be responsible for delivering research reports, simulation results, and functional scientific models. This opportunity is associated with NAICS code 541715 and is based in Greenbelt, Maryland. The response deadline for this requirement is December 4, 2026.

NASA Goddard Space Flight Center

POSTED

DEADLINE

Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) Innovative Solutions Opening

Solicitation # ARPA-H-SOL-26-160

The Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and Supplies (FASTPASS) program, under solicitation ARPA-H-SOL-26-160, is an initiative by the Advanced Research Projects Agency for Health (ARPA-H) to develop a near real-time, non-destructive, AI-enabled screening system. The goal is to identify contamination, adulteration, and quality defects in pharmaceutical products through their packaging at ports of entry and other supply-chain nodes using multi-modal sensing and data fusion. This 54-month program is structured into three 18-month phases, culminating in a fieldable platform with validated training materials and integrated documentation capabilities. This procurement is conducted as a multiple-award Other Transaction (OT) Agreement rather than a standard federal contract, meaning it is governed by specific OT articles instead of the Federal Acquisition Regulation. Awards are based on the most advantageous proposals, with primary evaluation factors including innovation, soundness, execution planning, risk management, and team expertise. Payments are fixed and triggered by the successful completion of milestones, managed through the Payment Management System. Proposers must be registered in SAM.gov and provide detailed technical and cost proposals, including a milestone payment schedule and research security disclosures. Amendment 01 specifically updated the cost proposal narrative model and workbook to correct typographical errors and rename appendices.

Advanced Research Projects Agency For Health (arpa-H)

POSTED

DEADLINE

HYDROSPHERE, BIOSPHERE, & GEOPHYSICS (HBG) SUPPORT SERVICES II - FINAL REQUEST FOR PROPOSAL (FRFP)

Solicitation # 80GSFC27R0015

The National Aeronautics and Space Administration Goddard Space Flight Center is soliciting proposals for the Hydrosphere, Biosphere, and Geophysics (HBG) Support Services II contract, under solicitation number 80GSFC27R0015. This small business set-aside is a hybrid Indefinite Delivery Indefinite Quantity (IDIQ) contract with a five-year effective ordering period. The contract allows for the issuance of both Cost Plus Fixed Fee (CPFF) and Firm-Fixed Price (FFP) task orders to support science research and computing activities across various laboratories, including the Cryospheric Sciences, Ocean Ecology, Hydrological Sciences, Biospheric Sciences, Geodesy and Geophysics, and the Terrestrial Information Systems Laboratory. The primary objective is to develop and apply space, field-deployed, and laboratory-based technologies to address societal issues related to water resources, ecosystems, sea level change, and the Earth's magnetic and gravity fields. The scope of work encompasses scientific modeling, simulation, data assimilation, satellite instrument performance analysis, and the planning and execution of field campaigns. Performance will occur at the Goddard Space Flight Center and the contractor's facilities, with acceptance managed by the Contracting Officer or a designated representative. Award selection will be based on a tradeoff approach, prioritizing Mission Suitability as the most important factor, followed by Cost and Past Performance. Proposals must be submitted in four volumes, including a numerically scored Mission Suitability volume and a detailed Cost volume. Additionally, the contractor must adhere to strict security requirements, including the provision of a Cyber Supply Chain Risk Management plan and compliance with NDAA Section 889 regarding telecommunications and surveillance equipment.

NASA Goddard Space Flight Center

POSTED

DEADLINE

Engineering Support for the Asymmetric Systems

Solicitation # N0017827R3106

Solicitation N0017827R3106 is a sources-sought effort for the Naval Surface Warfare Center Dahlgren Division to obtain comprehensive technical and engineering support for the Asymmetric Systems Division (H10). The anticipated contract will be a Cost-Plus-Fixed-Fee, Level of Effort Task Order with a five-year period of performance, consisting of a twelve-month base period and four twelve-month option periods. The primary objective is to provide qualified personnel to integrate advanced automation and asymmetric machine learning architectures into naval weapon systems across the entire acquisition lifecycle, from initial material solution analysis through testing and safe fielding. Work will be performed primarily at the Dahlgren, Virginia facility and at the contractor's own facilities. The scope of work is broad, encompassing multi-disciplinary engineering in domains such as software, mechanical, cyber, robotics, and RF micro-electronic design. Key deliverables include the development of data-driven validation frameworks, high-computing cloud services, and the implementation of Open Architecture standards. The contractor must adhere to strict security and quality requirements, including DFARS 252.204-7012 for system security plans and FAR 52.219-14 regarding subcontracting limitations. Award will be based on best value, evaluating technical capabilities, personnel qualifications and security clearances, and past performance as a prime contractor within the last five years. Invoicing will be managed through the Wide Area Workflow module on the Procurement Integrated Enterprise Environment system.

POSTED

DEADLINE

Notice of Change to Funding Opportunity: BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

Solicitation # NOT-NS-27-002

The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, has issued notice NOT-NS-27-002 regarding a funding opportunity titled BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies. This specific notice serves to inform the extramural community of a modification to the eligibility requirements for solicitation RFA-NS-27-015. The primary change allows for the inclusion of foreign components as defined by the NIH Grants Policy Statement. This update expands the scope of eligible applicants and partnerships for the U01 grant, though clinical trials remain disallowed under this specific funding opportunity.

National Institute Of Neurological Disorders And Stroke

POSTED

DEADLINE

Fisheries Biological Data Collection ServicesThe Fisheries Biological Data Collection Services subcontract involves providing detailed biological measurements for prime contractors working on projects for the Government of Canada's Department of Fisheries and Oceans. The scope of work includes measuring fish length and weight, determining sex and age composition, and performing gonad measurements and maturity analysis. To ensure the delivery of accurate biological data sets, the service provider must possess laboratory facilities specifically equipped for precision measurement and the handling of biological specimens. This opportunity is categorized under NAICS code 541715 and will be performed within Canada. Interested parties should note that the solicitation was posted on October 21, 2026, with a response deadline set for November 16, 2026. All work must strictly adhere to established technical requirements to maintain the integrity and accuracy of the biological data collected.

Department of Fisheries and Oceans

POSTED

DEADLINE

Subject Matter Expert (SME) and Mentor Program CoordinationThis subcontract for Empire State Development focuses on the recruitment and coordination of subject matter experts and mentors to support prime contractors on specialized projects. The primary objective is to identify and manage a roster of experts with deep domain knowledge in neurodegenerative disease research, specifically targeting Alzheimer’s, Parkinson’s, and ALS. The selected provider will be responsible for operating a mentor program for grantees, facilitating network meetings, and implementing a matching system between mentors and grantees. This effort falls under NAICS code 541715, with a response deadline set for November 18, 2026.

Empire State Development

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Transit Tech Lab Partnership Program

Solicitation # 2140101

NYSERDA is soliciting proposals under the Transit Tech Lab Partnership Program, identified as PON 6195, to implement innovative public transportation technologies and strategies across New York State. The program aims to advance clean transportation solutions for rail, transit bus, and connected intermodal systems. Selected projects must demonstrate a feasible path toward financial sustainability and be replicable and transferable for transit agencies of various sizes throughout the state. The contract term for these initiatives is up to 12 months, with performance occurring state-wide. Eligibility is strictly limited to companies that were competitively selected during the 2026 Transit Tech Lab application evaluation, participated in the TTL accelerator program, and were chosen as proof-of-concept finalists by the MTA or another New York transportation agency. Proposals are due by November 12, 2026, at 3:00 PM. While the solicitation includes goals for SDVOB, MBE, WBE, and DBE participation, all are currently set at 0.00 percent. Primary technical and project management is led by Richard Mai, with administrative and submission support provided by James Cowman and Jillina Baxter.

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Notice of Change in Application Due Date for NHLBI NOFOs PAR-25-025 and PAR-25-026

Solicitation # NOT-HL-27-002

This notice announces updates to the key dates for two National Heart, Lung, and Blood Institute funding opportunities, PAR-25-025 and PAR-25-026. These opportunities support early phase clinical trials for therapeutics and diagnostics related to heart, lung, and blood disorders. The primary purpose of the update is to add one additional receipt date for new applications as well as resubmission and revision applications. As a result of these changes, the expiration date for both notices of funding opportunity has been extended to February 4, 2027. A new application deadline has been established for February 3, 2027, with a corresponding earliest start date of December 2027. All other terms, conditions, and requirements of the original funding opportunities remain unchanged.

National Heart, Lung, And Blood Institute

POSTED

DEADLINE

Notice of Change in Application Due Date for PAR-25-032 "NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)"

Solicitation # NOT-HL-27-003

The National Heart, Lung, and Blood Institute has issued a notice regarding changes to the Notice of Funding Opportunity PAR-25-032 for Clinical Trial Pilot Studies. The primary purpose of this update is to extend the availability of the funding opportunity by adding an additional receipt date for new applications as well as resubmission and revision applications. As a result of these changes, the expiration date for the NOFO has been moved to March 17, 2027. All other terms, conditions, and requirements of the original solicitation remain unchanged. Applicants are reminded that all submissions must be received by 5:00 PM local time of the applicant organization.

National Heart, Lung, And Blood Institute

POSTED

1 day ago

DEADLINE

N/A

AI Contract Overview

This contract, awarded by the Administration for Strategic Preparedness and Response under the Department of Health and Human Services, focuses on the rapid implementation of a multi-site, randomized, double-blind clinical trial. The primary objective is to evaluate the safety and efficacy of Hydroxychloroquine, both alone and in combination with high-dose intravenous Famotidine, for treating hospitalized adults with moderate to severe COVID-19. The study compares these pharmaceutical antiviral interventions against the standard of care in patients who meet specific nucleic acid diagnostic and radiologic criteria. Beyond the primary drug combinations, the agreement allows for the exploration of additional dose-ranging strategies, the inclusion of other therapeutic compounds, and clinical sample testing to further refine COVID-19 treatments. Managed under solicitation number 75A50120C00078, the project is categorized under NAICS code 541715, emphasizing its nature as a specialized research and development effort to improve clinical outcomes for hospitalized patients.

General Info

Agency

Department Of Health And Human Services → Aspr Administration For Strategic Preparedness And Response

Contract Value

$4,668,079

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

DC, USA

Set-Aside

NONE

Awardee

ALCHEM LABORATORIES CORPORATION

Award Issued Date

04/14/2020, 12:00:00 AM UTC

Documents

No documents available

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Timeline

PhaseAwarded

PostedApr 22

Award Notice

AwardedApr 14

Contract was awarded

Submission Closed

04/14/2020, 12:00:00 AM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → Aspr Administration For Strategic Preparedness And Response

Contacts1 person available

OfficeWashington, DC, 20201, USA

Organization / AgencyDepartment Of Health And Human Services → Aspr Administration For Strategic Preparedness And Response

Office AddressWashington, DC, 20201, USA

Contacts

Carl Newman

contact@example.gov

+1 (555) 000-0000

Full Description

The objective of this contract is rapidly implement a multi-site, randomized, double-blind, multi-arm historical control, comparative trial of the safety and efficacy of Hydroxychloroquine and the combination of Hydroxychloroquine and Famotidine for the treatment of moderate to severe COVID-19 disease in hospitalized adults. The study will help evaluate the clinical efficacy of COVID-19 treatments consisting of standard of care (SOC) combined with pharmaceutical antiviral management using Hydroxychloroquine or SOC or SOL combine with Hydroxychloroquine and high-dose intravenous famotidine in hospitalized patients meeting nucleic acid diagnostic and radiologic criteria for COVID-19 disease. Additional dose-ranging or therapeutic strategies including additional therapeutic compounds, as well as clinical sample testing, to improve COVID-19 treatments are also proposed.

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