This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on May 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Multisizer 4e Coulter Counter
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The contract seeks the procurement of a Multisizer 4e Coulter Counter to support clinical research studies requiring precise cell sizing, counting, and distribution analysis via the Coulter method. The instrument must incorporate patented digital pulse processing technology to enable accurate measurements across a particle size range of 0.2 to 1,600 micrometers, with measurement linearity of ±1% for diameter and ±3% for volume, and a dynamic range of 1:40 in diameter and 1:64,000 in volume. It must support up to 400 size classes and process up to 525,000 time-stamped pulses per analysis, with modes for Total Count up to 500,000, Modal Count up to 100,000, and Volumetric Count up to 2,000 microliters. The system must include automatic aperture blockage detection and clearing, fluid level monitoring for solutions and waste, a barcode scanner for samples and consumables, and a stirrer with adjustable speed and direction to ensure uniform particle suspension. It must be compatible with aperture tubes ranging from 10 to 2,000 micrometers, with standard 100uM and 400uM tubes provided, and support use of 100mL and 200mL beakers along with other sample vessels as needed. The instrument must operate with Isoton II Diluent and Coulter Clenz cleaning solutions, including spigot assemblies, and be supplied with a Mixed Standards Kit and a 300uM Particle Standard for calibration. Installation is required as part of the deliverables, and the equipment must be delivered and set up at the designated performance location in Bethesda, Maryland, 20892. The solicitation, identified as 75N98026Q00434, is a presolicitation issued by the National Institutes of Health under the Department of Health and Human Services, with a response deadline of June 3, 2026, and no set-aside provisions apply. No pricing details, evaluation criteria, or contract administration data are provided in the available documentation.
General Info
Agency
NAICS
Place of Performance
MD, 20892, USASet-Aside
Timeline
Submission Closed
Organization & Contact Information
Full Description
The required Multisizer provides improved functionality and analysis capabilities, in addition to allowing continued measurement of cell size, counts, and distribution using the Coulter method across multiple clinical research study protocols.
Specifications & Requirements
The product shall include/use:
- Coulter method of measurement using patented digital pulse processing technology
- Automatic aperture blockage detection and clearing during runs and sample analysis
- Code scanner to scan bar codes on samples, electrolytes, aperture tubes, and sample beakers
- Fluid level monitoring for solutions and waste
- Selectable stirrer speed and direction
- Particle sizing range: 0.2 – 1,600uM
- Measurement range: 2 – 80% of aperture size
- Measurement linearity: Diameter ± 1%, Volume ± 3%
- Dynamic range (accuracy): 1:40 (diameter), 1:64,000 (volume)
- Accurate determination of sample cell number, size, distribution, and concentration
- Particle count, sizing, and volume distribution data, including diameter, volume, and area of number, number percent, number per mL, volume, volume percent, volume per mL, surface area, surface area percent, surface area per mL
- Pulse distribution data, including time, sequence and width for pulse height diameter, pulse height volume, pulse height volt, pulse width, pulse area, average pulse height diameter, average pulse height volume and average pulse width. Number distribution by width.
- Up to 400 size classes or channels with the ability to change number of size classes or channels and width and reprocess as needed without having to re-run the samples
- Time-stamped pulses up to 525,000 per single analysis
- Modes for Total Count (up to 500,000 counts), Modal Count (up to 100,000 counts), and Volumetric Count (up to 2000uL)
- Digital Pulse Processor with proprietary high-speed signal digitalization
- Real time detection of volume changes
- Stirrer with ability to adjust stir speed and direction for even particle distribution in sample suspensions
- 100uM and 400uM size aperture tubes, with instrument ability to use apertures ranging from 10uM up to 2000uM size as needed, with aperture tube calibration and verification
- 100/200mL beakers, with ability to use additional size beakers and accuvettes, as required by the sample type, sample volume, or other need
- Isoton II Diluent and Coulter Clenz solutions for instrument operation and cleaning, and spigot assemblies for both solutions
- Mixed Standards Kit (L2, L5, L10, L20, L40)
- 300uM Particle Standard
- Installation
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