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This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on January 30, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Notice of Intent - Nucleic acid–based reagents for in vivo transient protein expression

Closed
NIH-26-006363-IntentNoticeFederal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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POSTED

2 days ago

DEADLINE

in 23 days
NAICS: 325413
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6550--HEMOCHRON SIGNATURE ELITE REAGENTS AND SUPPLIES
Solicitation # 36C26227Q0046
The Department of Veterans Affairs, Network Contracting Office 22, is conducting a sources sought notice for the procurement of FDA approved reagents, supplies, consumables, and quality control materials for Werfen Hemochron Signature Elite instruments. This requirement supports the Pathology and Laboratory Medicine Service at the Southern Arizona VA Health Care System in Tucson, Arizona. The contract structure includes a base year from January 1, 2027, to December 31, 2028, followed by four subsequent option years extending through December 31, 2032. The selected contractor must provide 24/7 technical and product support at no additional cost and ensure all items are fully compatible with existing instrumentation without requiring workflow changes or retraining. Key operational requirements include strict adherence to manufacturer specifications for packaging and temperature control during transport. All supplied materials must maintain a minimum shelf life of 90 days, and shipments must clearly list lot numbers and expiration dates. Standard orders are required to be delivered within four working days, while emergency deliveries for defective or temperature-compromised items must be completed within 24 hours of a verbal order. This procurement is conducted as a brand name or equal acquisition under FAR 52.211-6. Interested respondents must provide their business size status, SAM.gov identifiers, and evidence of compliance with the Buy American Act and the Non-Manufacturer Rule.
262-NETWORK Contract Office 22 (36C262)

POSTED

3 days ago

DEADLINE

in 12 days

General Info

NAICS

325413 - In-Vitro Diagnostic Substance Manufacturing

Place of Performance

Philadelphia, PA, 19104, USA

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

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Timeline

PhaseClosed
Posted

Presolicitation

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Program Support Center Acq Management Svc
Contacts1 person available
OfficeROCKVILLE, MD, 20857, USA
Office AddressROCKVILLE, MD, 20857, USA
Contacts

Full Description

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This notice is not a request for competitivequotations or capability statements. The intent of this notice is for informational purposes only. 


Please do not call or submit questions/inquiries via email, concerning this presolicitation notice update.


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The intent is to award a contract on a solesource basis for Nucleic acid–based reagents for in vivo transient protein expression for the National Cancer Institute and Center for Cancer Research to: 


Trustees of The University of Pennsilvania - Penn Medicine


3451 Walnut Street


Philadelphia, PA


19104, USA



The supplies required are nucleic acid-based reagents. 


The proposed work focuses on the use of nucleic acid-based reagents to investigate preventive strategies against viral infection of HIV/Simian Immunodeficiency virus (SIV) and HTLV in preclinical models. The proposed studies will utilize nucleic-acid based reagents that express viral antigens as a preventive treatment to be tested in appropriate models.


Nucleic acid-based reagents have been used in prior preclinical studies, conducted by the AMRVS, as preventive countermeasures against viral infections, demonstrating the ability to induce protective immune responses in relevant experimental models. Previous work has shown that such reagents can be designed to express viral antigens that are safe and confer protection against the target pathogen. Collectively, these findings support further preclinical studies as preventive strategies. The requested reagents will provide broader activity against related viral subtypes and other cancer-inducing viruses. It is important to use the same supplier  for these reagents in order to ensure consistency with materials used in previous preclinical studies. These reagents can vary in formulation, synthesis methods and purity, and such differences may introduce variability that complicates interpretation of experimental results. Using reagents from the same suppliers enables direct comparison with previously generated data, support reproducibility and ensure continuity in experimental design and data analysis.

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