This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on May 18, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Notice of Intent to issue a Sole Source Award to generate and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in both plate-based assays and POC platforms.

Closed

75D30126R73457Federal

Submission Closed06/02/2026, 05:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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in 7 months

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AI Contract Overview

The Centers for Disease Control and Prevention (CDC) Division of HIV Prevention intends to issue a sole source fixed-price contract to the University of North Carolina at Chapel Hill's Department of Chemistry. The purpose of this contract is to generate and optimize high-affinity nucleic acid aptamers that can semi-quantitatively detect TFV-DP and/or TFV. These aptamers will be used in both plate-based assays and point-of-care platforms. This contract is being awarded under FAR 12.102-1, allowing negotiation with a single source due to UNC's unique qualifications, including its role as co-inventor of a previously-developed FTC aptamer critical to antiretroviral detection research and the compatibility of its methodologies with the CDC’s existing assay development. UNC is considered the only source capable of meeting the technical requirements and timeline necessary for this work, as switching to another vendor would disrupt progress by necessitating a complete redo of the optimization process and would not align with current aptamers for emtricitabine detection. This notice is not a solicitation for competitive bids, though the CDC will consider any responses received within 15 days of issuance for the purpose of evaluating whether to proceed with a competitive procurement. Responses should be submitted by June 2, 2026, and any decision not to complete the contract based on received input remains at the government’s discretion. The contract aligns with NAICS code 541715 for Medical Research and Development Laboratories or Services and will be performed primarily in Chapel Hill, North Carolina.

General Info

CDC awards sole source contract to UNC for developing aptamers detecting TFV-DP/TFV in assays.

Agency

Department Of Health And Human Services → CDC Office Of Acquisition Services

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Chapel Hill, NC, 27599, USA

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PhaseClosed

PostedMay 18

Presolicitation

Response DeadlineJun 2

Deadline has passed

Submission Closed

06/02/2026, 05:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → CDC Office Of Acquisition Services

Contacts2 people available

OfficeATLANTA, GA, 30333, USA

Organization / Agency

Department Of Health And Human Services → CDC Office Of Acquisition Services

Office AddressATLANTA, GA, 30333, USA

Contacts

Eugene L. Gutierrez Jr

Liubov Kriel

Full Description

The Centers for Disease Control and Prevention Division of HIV Prevention (DHP)/Laboratory Branch intends to award a sole source Firm-fixed-price purchase order to the University of North Carolina at Chapel Hill, Department of Chemistry to generate and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in both plate-based assays and POC platforms. This contract action is for commercial services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 12.102-1. NAICS 541715 - Medical Research and Development Laboratories or Services (except Biotechnology and Nanotechnology Research and Development). UNC was identified as uniquely qualified due to its role as a co-inventor of the FTC aptamer previously developed for ARV detection research, and established methodologies compatible with CDC’s current assay development efforts. UNC is the only source reasonably available capable of performing the required work within the required timeframe and technical specifications. Changing to another vendor’s aptamer would severely impact the CDC’s progress in this area, requiring a start over of the entire process of optimization and would not be compatible with the already developed, existing aptamer detecting emtricitabine. This notice of intent is not a request for competitive quotations; however, all Quotations/ responses received within 15 days of the issuance of this notice shall be considered by the government. A determination by the government not to complete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to the contract specialist at email zvm0@cdc.gov by 06/02/2026.