This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on May 18, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Notice of Intent to issue a Sole Source Award to generate and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in both plate-based assays and POC platforms.

Closed

75D30126R73457Federal

Submission Closed06/02/2026, 05:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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AI Contract Overview

The Centers for Disease Control and Prevention’s Division of HIV Prevention intends to award a sole-source firm-fixed-price purchase order to the University of North Carolina at Chapel Hill’s Department of Chemistry to develop and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of tenofovir diphosphate and/or tenofovir for use in both plate-based and point-of-care diagnostic platforms. The work is classified as commercial services under NAICS code 541715, and the selection of UNC is based on its unique qualifications as a co-inventor of a previously developed aptamer for antiretroviral detection, along with established methodologies that align with the CDC’s ongoing assay development. Switching vendors would halt progress, as alternative aptamers are incompatible with existing reagents and would require restarting the entire optimization process from scratch. This is a presolicitation notice, not a competitive solicitation, and while responses may be submitted by June 2, 2026, to the designated email address, the government retains full discretion to proceed with or without competitive bidding. The place of performance is Chapel Hill, North Carolina, and all technical inquiries should be directed to the primary point of contact, Eugene L. Gutierrez Jr., at zvm0@cdc.gov.

General Info

CDC awards sole source contract to UNC for developing aptamers detecting TFV-DP/TFV in assays.

Agency

Department Of Health And Human Services → CDC Office Of Acquisition ServicesView Agency

Contract Value

$330,000

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Chapel Hill, NC, 27599, USA

Set-Aside

NONE

Awardee

UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILLView Profile

Award Issued Date

09/04/2026, 12:00:00 AM UTC

Documents

(0)

No documents available

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Timeline

PhaseClosed

PostedMay 18

Presolicitation

Response DeadlineJun 2

Deadline has passed

Submission Closed

06/02/2026, 05:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → CDC Office Of Acquisition Services

Contacts2 people available

OfficeATLANTA, GA, 30333, USA

Organization / Agency

Department Of Health And Human Services → CDC Office Of Acquisition Services

View Agency Profile

Office AddressATLANTA, GA, 30333, USA

Contacts

Eugene L. Gutierrez Jr

Liubov Kriel

Full Description

The Centers for Disease Control and Prevention Division of HIV Prevention (DHP)/Laboratory Branch intends to award a sole source Firm-fixed-price purchase order to the University of North Carolina at Chapel Hill, Department of Chemistry to generate and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in both plate-based assays and POC platforms. This contract action is for commercial services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 12.102-1. NAICS 541715 - Medical Research and Development Laboratories or Services (except Biotechnology and Nanotechnology Research and Development). UNC was identified as uniquely qualified due to its role as a co-inventor of the FTC aptamer previously developed for ARV detection research, and established methodologies compatible with CDC’s current assay development efforts. UNC is the only source reasonably available capable of performing the required work within the required timeframe and technical specifications. Changing to another vendor’s aptamer would severely impact the CDC’s progress in this area, requiring a start over of the entire process of optimization and would not be compatible with the already developed, existing aptamer detecting emtricitabine. This notice of intent is not a request for competitive quotations; however, all Quotations/ responses received within 15 days of the issuance of this notice shall be considered by the government. A determination by the government not to complete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to the contract specialist at email zvm0@cdc.gov by 06/02/2026.