Olink Explorer >5400

The contract seeks a high-throughput proteomics platform capable of simultaneously measuring over 5,400 human proteins using Proximity Extension Assay technology with dual antibody recognition, DNA barcoding, and next-generation sequencing readout. It requires minimal sample input—just two microliters of plasma or serum—while delivering exceptional specificity at 99.5% due to the dual-antibody design and an expansive dynamic range spanning ten orders of magnitude, enabling detection of proteins from femtogram to milligram per milliliter concentrations. The platform must offer excellent sensitivity for low-abundance circulating proteins, particularly cytokines and signaling molecules, while maintaining broad proteome coverage with high reproducibility and standardization, making it suitable for large-scale epidemiological and multi-omics studies. The solicitation, issued by the National Institutes of Health under the Department of Health and Human Services, is cataloged under NAICS code 541380 and is titled Olink Explorer >5400. Responses are due by July 25, 2026, and the opportunity is open without any set-aside restrictions. The primary point of contact is John Burton at the NIH office in Bethesda, Maryland, with the procurement managed through the SAM.gov portal. The technology must meet rigorous performance benchmarks to support the lab’s research on inflammation, innate immunity, and the gut microbiome’s role in cancer development, progression, and therapeutic response.