This Special Notice opportunity from Department Of Health And Human Services was posted on November 24, 2021. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Posting of the DRFP Comments for the National Cancer Institute's (NCI) supporting the NCI Federally Funded Research and Development Center (FFRDC)/Frederick National Laboratory for Cancer Research (FNLCR)

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HHS-NIH-NCI-SN-MOSB-75N91020R00062-19Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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Digital Health Sandbox Environment & Validation ServicesThe Digital Health Sandbox Environment and Validation Services subcontract, issued by the Massachusetts Technology Collaborative, establishes a controlled testing ground for digital health companies working with prime contractors on MassTech and MeHI rural health projects. The initiative provides the necessary infrastructure and clinical settings to test, validate, and pilot healthcare products, with a specific focus on improving the quality and accessibility of healthcare in rural areas. The selected provider is responsible for tracking performance data and delivering comprehensive impact reports to measure the effectiveness of these digital health solutions. Due to the nature of the funding, strict adherence to 2 CFR 200 and Single Audit Act compliance is required. Interested parties must submit responses by December 7, 2026, for work to be performed in Westborough, Massachusetts.

Massachusetts Technology Collaborative

POSTED

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NOFO 2027-MeHI-02 Rural Digital Health Sandbox Program

Solicitation # BD-27-1367-1367C-1367L-135347

The Massachusetts Technology Collaborative (MassTech) is issuing the Rural Digital Health Sandbox Program (NOFO 2027-MeHI-02) to support digital health companies in testing and validating new products and services within authorized sandbox environments. Funded by the Centers for Medicare & Medicaid Services under the Rural Health Transformation Program, the initiative aims to improve healthcare access, quality, and outcomes within rural communities in Massachusetts. Selected applicants are eligible for grant funding up to $475,000, which is paid directly to the participating sandbox organizations rather than the applicants. Applicants must submit a comprehensive application by December 7, 2026, including a pitch deck, project plan, budget, team bios, a W9, and a signed letter of support from their chosen sandbox. Evaluation is based on commercial viability, the potential to improve rural healthcare, project feasibility, and the ability to scale solutions. A critical requirement for all applicants is a lack of debarment status by both state and federal governments. Sandbox providers receiving these funds must adhere to 2 CFR 200 Uniform Guidance and the Single Audit Act if federal expenditures exceed $1,000,000.

Massachusetts Technology Collaborative

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Replicable, Actionable Projects for Intelligent Transportation Systems (ITS) Deployment, Broad Agency Announcement (RAPID BAA)

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DEADLINE

Oil Spill Response and Mesoscale Testing Subject Matter ExpertThis subcontract opportunity is for an Oil Spill Response and Mesoscale Testing Subject Matter Expert to provide technical analysis for prime contractors on BSEE/MMA projects under the Department of the Interior. The selected expert will focus on analyzing mesoscale oil testing protocols to validate technology readiness and establishing the correlation between mesoscale results and full-scale performance. Key responsibilities include developing technical criteria for TRL gates for oil spill response technologies by leveraging knowledge of the Ohmsett Branch testing facility. Additionally, the contractor will provide critical technical inputs and data analysis to support the development of the TRL Guidebook and the T&E approach document. The solicitation was posted on November 10, 2026, with a response deadline of November 25, 2026.

Bsee Contracting Activity

POSTED

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Modeling, Simulation, and Tabletop Exercise SupportThis small business set-aside subcontract focuses on providing modeling, simulation, and tabletop exercise support for the Department of Defense at the NSWC Indian Head Division. The scope of work involves the development and execution of simulations for One-Way Attack and Unmanned Systems, utilizing high-performance computing environments to support prime contractors on various weapons systems. The selected provider will be responsible for conducting verification, validation, and accreditation in accordance with DoD 5000.61 standards. Key deliverables include the simulation models themselves, comprehensive VV&A reports, and summaries from tabletop exercises. The opportunity is categorized under NAICS code 541715, with a response deadline set for November 24, 2026.

Nswc Indian Head Division

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Electronic Warfare (EW) & Digital Signal Processing (DSP) DevelopmentThis small business set-aside subcontract focuses on the design and development of analog and digital signal processing systems for prime contractors supporting the Department of Defense at the NSWC Indian Head Division. The scope of work includes preparing workstations for the DSP Laboratory, creating signal processing systems for threat-informed technology improvements, and performing electronic warfare hardening analysis in accordance with MIL-STD-461. The successful contractor will be responsible for delivering functional DSP workstations, specialized signal processing hardware, and detailed threat analysis reports. This effort falls under NAICS code 541715 and is centered in the 20640 zip code area, with a response deadline set for November 24, 2026.

Nswc Indian Head Division

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Acoustic Source Characterization SpecialistThis subcontract opportunity for an Acoustic Source Characterization Specialist supports US Space Force launch noise analysis projects. The selected provider will perform literature reviews and technical characterizations of acoustic signatures for prime contractors, focusing specifically on research regarding sonic booms and launch acoustics for several major vehicles, including Falcon 9, Falcon Heavy, Starship/Super Heavy, Vulcan, and New Glenn. The scope of work involves utilizing signal analysis software and aerospace acoustic databases to develop a comprehensive Acoustic Source Characterization Database. Key deliverables for this effort include the final database and a Phase 1 Report. The work is associated with the Department of Defense and is to be performed in Cape Canaveral, Florida, with a response deadline of December 3, 2026.

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Notice of Intent To Award Sole Source WHOI REMUS Support

Solicitation # N6660427RB700

Nuwc Division Newport

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Area of Interest: OSW Cost Assessment and Program Evaluation (CAPE) Modeling and Simulation

Solicitation # HQ003427AOI5

The Department of War Cost Assessment and Program Evaluation CAPE is seeking innovative commercial solutions to replace its legacy modeling and simulation infrastructure with a next-generation computational backbone. The objective is to modernize decision support by implementing a three-layer architecture consisting of a high-performance simulation execution layer, a machine-learned surrogate emulation layer for government-developed models, and an intuitive self-service quantitative analysis layer. This system must dramatically increase throughput, with the capability to execute between 1,200 simulations in 10 hours for light cases and up to 150,000 simulations within two weeks for heavy joint campaign cases. The required solution must operate at Impact Level 6 security accreditation to be accessible from secure spaces at the Pentagon and Mark Center, supporting network throughput between 100 Mbps and 1 Gbps. Technical requirements include compatibility with Python, R, Java, PyTorch, GAMS, and containerized processes. While the commercial provider will manage turnkey platform and infrastructure IT operations, including cybersecurity hardening and patching, the government will retain full operational tenant administration and control over data and user access. This procurement is being conducted as a Commercial Solutions Opening with a Rough Order of Magnitude estimate between 3 million and 22 million dollars. Phase I evaluations focus on the relevance of the solution brief, specifically regarding technical ability, scalability, and security posture. Initial operational capability is anticipated in FY27, with full operational capability expected in FY28. Solution briefs are due by November 16, 2026.

Washington Headquarters Services

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SYSTEM DELTA 84 (SYD 84/MT) MEDIUM EARTH ORBIT MISSILE WARNING / MISSILE TRACKING EPOCH 3 and EPOCH 4, REQUEST FOR INFORMATION (RFI)

Solicitation # FA8810-RFI-26-SYD84-E3E4

Space Systems Command is seeking industry feedback through a Request for Information regarding the production feasibility of Epochs 3 and 4 for the Resilient Missile Warning and Tracking Medium Earth Orbit layer. The government is looking for technical approaches and acquisition strategies to support Full Warfighting Capabilities, specifically focusing on space vehicle delivery, integration, and operations, ground segment command and control facilities, and digital engineering integration. The intended contract structure is a Firm Fixed Price agreement utilizing Other Transaction Authority. The response deadline for this effort is December 2, 2026, with a maximum page count of 50 pages. This opportunity is categorized under NAICS code 541715, and the government strongly encourages participation from small and disadvantaged businesses. Interested vendors must coordinate with government points of contact to receive full documentation, and those seeking classified information must possess at least a Secret facility clearance.

FA8810 Space Sensing Ssc/snk

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Solicitation # HT9427-27-SSN-701

The Defense Health Agency Contracting Activity, acting for the Portfolio Acquisition Executive for Medical Products and the Warfighter Protection and Acute Care Project Management Office, intends to issue a sole-source contract modification to Westat Inc. This action is designed to update the SAFE-PLASMA Protocol clinical trial design to align with FDA recommendations and ensure the trial is conducted in accordance with Good Clinical Practices (GCP). The primary objective is to evaluate the safety of EZPLAZ and conventional plasma products in adult patients to meet the necessary requirements for EZPLAZ approval. The scope of work includes the implementation of a specific protocol and Statistical Analysis Plan. This effort is categorized under NAICS code 541715 and is managed by the Defense Health Agency with performance located in Maryland. As this is currently a Sources Sought Notice for market research and planning purposes, the agency is seeking capability statements from interested sources, including technical data and rough order of magnitude estimates, to be submitted via email by November 16, 2026.

Defense Health Agency

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NIMHD Division of Intramural Research Population Health and Clinical Research — Small Business Sources Sought

Solicitation # 75N94027R00005

The National Institute on Minority Health and Health Disparities (NIMHD) is conducting market research via a Small Business Sources Sought notice to identify qualified small businesses capable of providing research and development social and behavioral sciences services. The objective is to support the NIMHD Division of Intramural Research in conducting population health and clinical research aimed at understanding and reducing health disparities in the United States. The government anticipates awarding an Indefinite Delivery Indefinite Quantity (IDIQ) contract around September 2027. The scope of work involves designing and overseeing clinical and technical investigations using methods such as epidemiological studies, clinical trials, and qualitative research, while managing the recruitment of participants and the coordination of multiple research sites. The required services include comprehensive project management, regulatory compliance assurance, and the provision of qualified personnel, including medical, nursing, and neuropsychologic staff. Contractors must ensure adherence to Good Clinical Practices (GCP), Good Clinical Laboratory Practices (GCLP), and FISMA security standards, while managing FDA-compliant reporting for adverse experiences. This effort is categorized under NAICS code 541715, with a small business size standard of 1,000 employees or less. Interested small businesses must submit an electronic capability statement of 20 pages or less to the Contracting Officer and Contract Specialist by November 25, 2026, detailing their business status, UEI, and CAGE code.

National Institutes Of Health Olao

POSTED

1 day ago

DEADLINE

in 14 days

AI Contract Overview

This contract notice pertains to the National Cancer Institute's release of responses to comments on a Draft Request for Proposals (DRFP) originally issued on June 24, 2021, supporting the NCI Federally Funded Research and Development Center and the Frederick National Laboratory for Cancer Research. It is a special notice intended solely to share the finalized document addressing the comments received on the DRFP and is not a solicitation for new proposals or quotations. Interested parties are directed to review the document titled "DRFP1 to DRFP2 QA Final." Additional details regarding the competitive process and any future updates will be made available through the official government-wide point of entry at beta.sam.gov and the FNLCR Acquisition Portal. The notice emphasizes that information posted on SAM.gov holds precedence and is considered the authoritative source. Questions or inquiries related to the acquisition process can be directed to the FNLCR Acquisition Team via the provided email contacts. The contract is managed by the National Cancer Institute under the Department of Health and Human Services, with offices located in Bethesda, Maryland.

General Info

National Cancer Institute releases finalized responses to DRFP comments; no new proposals requested.

Agency

Department Of Health And Human Services → NIH Nci

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Set-Aside

NONE

Documents

q-and-a

High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

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Timeline

2 updates

PhaseClosed

PostedNov 24

special-notice

Notice updatedNov 24

The notice description changed.

Notice updatedNov 24

Notice details unchanged. Attachments may have changed.

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → NIH Nci

Contacts2 people available

OfficeBethesda, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → NIH Nci

Office AddressBethesda, MD, 20892, USA

Contacts

Lisa Coleman

contact@example.gov

Don Mills

contact@example.gov

Full Description

PURPOSE: THIS IS A SPECIAL NOTICE. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this Special Notice is to provide the release of the responses to DRFP comments for the DRFP released on 24 June 2021. Please find the document entitled - DRFP1 to DRFP2 QA Final attached. ADDITIONAL INFORMATION: Additional information concerning the competitive process for the contract will be announced on https://beta.sam.gov/ as well as at the FNLCR Acquisition Portal: https://www.cancer.gov/about-nci/contracts/fnlcr-acquisitions/. The information posted to SAM takes precedence over information provided elsewhere and serves as the Government's official government-wide point of entry (GPE). If you have questions, please email the FNLCR Acquisition Team at: contact@example.gov (contact@example.gov).