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This Solicitation opportunity from Department Of Health And Human Services was posted on October 3, 2024. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

PREDICTIONS FOR REAL-TIME OPTIMIZATION OF MICROBIOMES OF BUILT ENVIRONMENTS (PRO-MICROBE) EXPLORATION TOPIC

Closed
ARPA-H-MAI-24-01-06Federal

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The ARPA-H is issuing a solicitation for the PRO-MICROBE Exploration Topic, which aims to develop innovative models to assess and predict the health impact of indoor microbial communities through a microbiome of the built environment (MoBE) health index. This initiative seeks to leverage non-biological data to create real-time predictive tools that can inform building design and engineering practices to promote occupant health and prevent pathogenic colonization. The program emphasizes rapid, targeted awards aligned with the RSO’s mission to foster high-impact biomedical research addressing significant health challenges. The solicitation, posted on October 3, 2024, invites proposals due by November 4, 2024, with all submissions to be made through the designated ARPA-H portal. The announcement has undergone three amendments to update templates, clarify proposal instructions, extend deadlines, and reference the latest Master Announcement Instructions. Questions regarding the program should be directed via the specified ARPA-H question portal. The contract is managed by the National Institutes of Health under the Department of Health and Human Services, with a focus on advancing innovative health solutions through strategic research efforts.

General Info

Develop novel models predicting indoor microbiome health indices, supporting optimal human health.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

MD, USA

Set-Aside

NONE

Documents

7

ARPA-H-MAI-24-01-06 PRO-MICROBE Amendment 1

PDF, High priority: read this firstamendment
High

ARPA-H-MAI-24-01-06 PRO-MICROBE Amendment 2

PDF, High priority: read this firstamendment
High

ARPA-H-MAI-24-01-06 PRO-MICROBE Amendment 3

PDF, High priority: read this firstamendment
High

ARPA-H-MAI-24-01-06 PRO-MICROBE Exploration Topic

PDF, High priority: read this firstrfp
High

ARPA-H-MAI-24-01 Master Announcement Instruction Amendment 1

PDF, High priority: read this first18 pages · amendment
High

ARPA-H-MAI-24-01 Master Announcement Instruction Amendment 2

PDF, High priority: read this first18 pages · amendment
High

PRO-MICROBE OT Bundle of Attachments_Amendment 3.zip

ZIP

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Timeline

1 update
PhaseClosed
Posted

Presolicitation

Type Changed

Presolicitation → Solicitation

Notice updated

Response deadline changed from Oct 4, 2024 to Nov 4, 2024. The notice description changed.

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH
Contacts1 person available
OfficeBethesda, MD, 208920004, USA
Office AddressBethesda, MD, 208920004, USA

Full Description

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Amendment 3 (posted October 3, 2024): The purpose of this amendment is to: 1) update Volume 1: Technical & Management and the Administrative & National Policy Requirements template documents; 2) reference the latest Amendment to the Master Announcement Instruction (MAI), ARPA-H-MAI-24-01 throughout the Module Announcement; and 3) make administrative updates to clarify metrics and highlight the importance of having access to a pre-defined built environment type at proposal submission. No other changes to the Attachment 1, OT Bundle templates have been made. However, for ease, all Attachment 1, OT Bundle templates are being provided with Amendment 3 and previous versions of Attachment 1, OT Bundle templates have been removed to avoid confusion.


Amendment 2 (posted September 11, 2024): The purpose of this amendment is to: 1) Extend the proposal due date and associated Q&A due and release dates; 2) Clarify and revise proposal preparation instructions in Section 6(A), Module Announcement Responses: Proposal Preparation instructions; 3)Provide proposal preparation instructions associated with Section 6(A)(3)(e), ModuleAnnouncement: Proposal Preparation instructions, MoBE Health Index; 4) Provide the link to where the PRO-MICROBE module announcement is posted on the ARPA-H webpage in Section 10, Question and Answers (Q&As); and 5) Update Section 1, Executive Summary, of Volume 1: Technical & Management Template of the OTBundle (Attachment 1). All changes are highlighted in yellow. No other changes to the Attachment 1, OT Bundle templates have been made. However, for ease, all Attachment 1, OT Bundle templates are being provided with Amendment 2.


Amendment 1 (posted August 22, 2024): The purpose of this amendment is to update Section 3 of Volume 1: Technical & Management Template in the OT Bundle (Attachment 1). All changes are highlighted in yellow. No other changes to this Moduluar Announcement or to the Attachment 1, OT Bundle templates have been made. However, for ease, all Attachment 1, OT Bundle templates are being provided with Amendment 1.


ARPA-H is launching an Exploration Topic (ET) aimed at expanding the Resilient System Office’s (RSO) funding approach associated with the interest areas included within Appendix A to the Master Announcement Instructions, ARPA-H-MAI-24-01. Exploration Topics will be announced via Module Announcements issued under the Master Announcement Instructions (MAI), ARPA-H-MAI-24-01. Exploration Topics are short-duration, fast-paced efforts with smaller, targeted awards. Each Exploration Topic will pursue topics that strategically align with the RSO mission and provide foundational proofs-of-concept for additional future research to be built upon.


The mission of the Advanced Research Projects Agency for-Health (ARPA-H) is to accelerate better health outcomes for everyone by advancing innovative research that addresses society's most challenging health problems. Awardees will develop groundbreaking new ways to tackle health-related challenges through high potential, high-impact biomedical and health research. ARPA-H is seeking proposals that will integrate innovative microbial sampling tools with advanced analytical methods to develop a microbiome of the built environment (MoBE) health index that scores the health impact of an indoor microbiome. The Predictions for Real-time Optimization of MICRObiomes of Built Environments (PRO-MICROBE) Exploration Topic endeavors to develop novel models using non-biological data that can predict MoBE health indices of specific indoor environments. By creating new ways to assess and predict the impact of indoor microbial communities on occupant health outcomes, PRO-MICROBE seeks to transform how building design and engineering can support microbial communities important for optimal human health while resisting the colonization of pathogenic microorganisms.


All questions regarding PRO-MICROBE must be sent to https://solutions.arpa-h.gov/Ask-A-Question.


Stage 1, Volume 1 proposals should be submitted ONLY to https://solutions.arpa-h.gov/, and the due date is no later than November 4, 2024.


Please see the attached Final module announcement for full program along with Attachment 1, OT Bundle which contains templates and proposal preparation instructions. Additionally, ARPA-H-MAI-24-01 Master Announcement Instructions (MAI) Amendment 2 has been provided for ease.

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DEADLINE

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