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Py-GC/MS for Micro- and Nanoplastic Analysis

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75N992-26-SS-106Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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The Advanced Research Projects Agency for Health (ARPA-H) Health Science Futures Office has issued a sources sought notice to evaluate industry interest and capabilities regarding specialized analytical services. The agency is seeking organizations with the expertise to provide gold-standard Pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) analysis. This technical requirement focuses on the detection and analysis of micro- and nanoplastics (MNPs) within various biological samples, including blood, urine, and tissue. This solicitation, identified by number 75N992-26-SS-106, serves as a market research tool to identify vendors with relevant experience in high-precision chemical analysis for health science applications. Interested parties must submit their responses by the deadline of September 8, 2026. The procurement falls under NAICS code 334516 and is managed by the Department of Health and Human Services.

General Info

ARPA-H seeks vendors for Py-GC/MS analysis of microplastics in biological samples by September 2026.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

334516 - Analytical Laboratory Instrument ManufacturingView NAICS

Place of Performance

77416, DC, USA

Set-Aside

NONE

Documents

(1)

SS_75N992-26-SS-106_082426.pdf

PDF

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Timeline

PhaseSources Sought
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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Organization / Agency
Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
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Office AddressWashington, DC, 20005, USA
Contacts
The STOMP Team
contact@example.gov

Full Description

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The intent of this Sources Sought notice is to gauge industry interest, capabilities, and relevant experience to support Advanced Research Projects Agency for Health (ARPA-H) Health Science Futures Office (HSF) by providing gold-standard Pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) analysis of micro- and nanoplastics (MNPs) in biological samples, such as blood, urine and tissue.


Specifically, ARPA-H is looking for the capability to perform Py-GC/MS analysis of MNPs in biological samples.


See attached for sources sought request and response instructions. 

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Technology InteGrator and AcceleratoR (TIGAR)
Solicitation # ARPA-H-SOL-26-144
The Technology InteGrator and AcceleratoR (TIGAR) solicitation, issued by the Advanced Research Projects Agency for Health (ARPA-H) under number ARPA-H-SOL-26-144, seeks innovative solutions to enable temperature-flexible storage of complex regenerative tissues and organs, removing reliance on strictly controlled cryogenic conditions. The effort targets functional preservation of organoids, donated tissues, whole organs, or one-cubic-centimeter tissue volumes for at least 30 days at practical temperatures: -80°C, -20°C, 4°C, or 20°C–25°C room temperature, using novel combinations of materials, AI/ML, high-throughput screening, biological interventions, devices, or packaging approaches. The project is structured as an 18-month period of performance divided into two nine-month phases, with a down-select decision at the end of Phase 1. Proposals must align with HHS health IT standards, promote open-source software licensing (MIT, BSD, Apache 2.0), enhance data interoperability, and avoid low-risk or junior-staffed approaches designed solely for cost appearance. Funding is capped at $2 million per award, and only proposals submitted through the ARPA-H Solution Submission Portal will be considered. The solicitation allows multiple Other Transaction (OT) agreements and does not use a set-aside. Submission follows a two-step process: first, a 7-minute Solution Video with a transcript and supplemental slides, and second, a Full Proposal including technical, management, cost, and administrative documentation. The Solution Video deadline for Intake Group 1 has been amended to August 12, 2026, with the Full Proposal deadline extended to September 17, 2026; Intake Group 2 deadlines remain December 8, 2026, and February 5, 2027, respectively. All materials must be submitted via the ARPA-H portal, in English, using sans-serif 11-point fonts, with file names free of spaces or symbols. Evaluation prioritizes scientific and technical merit, proposer capabilities, alignment with ARPA-H’s mission and user needs, and cost realism. Proposal teams must hold valid SAM.gov registrations with active UEIs, provide good faith representations of intellectual property ownership, disclose organizational conflicts of interest, and ensure compliance with federal research security regulations, including prohibitions against involvement with malign foreign talent programs or entities of concern under the CHIPS and
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

in 6 months
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NAICS: 541715
Federal
Brain Repair of Any Injured Neural Structure (BRAINS)
Solicitation # ARPA-H-SOL-26-148
The Advanced Research Projects Agency for Health (ARPA-H) is seeking innovative solutions through the Brain Repair of Any Injured Neural Structure (BRAINS) Exploratory Topic program under solicitation ARPA-H-SOL-26-148, which utilizes Other Transaction (OT) agreements rather than standard federal contract mechanisms. The program aims to advance technologies capable of restoring function to damaged brain regions—specifically targeting areas such as the hippocampus, amygdala, thalamus, hypothalamus, striatum, cingulate cortex, substantia nigra, brainstem, and cerebellum—by generating and engrafting region-specific precursor tissue, while explicitly excluding the neocortex and spinal cord as well as conventional cell or organoid-based approaches. Proposers must submit a mandatory solution summary prior to full proposal submission, with two intake cycles: the first requiring solution summaries by July 9, 2026, and full proposals by August 6, 2026; the second, with deadlines of January 7, 2027, and February 6, 2027, respectively. Proposals must be submitted via the ARPA-H Solution Submission Portal and must conform to a strict three-volume structure: Volume I (Technical and Management Proposal with a 10-page limit for core content), Volume II (Cost Proposal using the ARPA-H Standard Excel Spreadsheet and supporting narrative), and Volume III (Administrative and Policy Requirements including certifications for organizational conflicts of interest, research security, biosecurity, cyber practices, animal research approvals, and tax compliance). Awardees will be evaluated based on the scientific and technical merit of the approach, the proposer’s expertise, potential for clinical and commercial impact aligned with ARPA-H’s mission, and the reasonableness of the proposed cost, with no preset weighting but ranked in descending importance. Phase I awards are anticipated at $500,000 per team with optional Phase II funding up to an additional $500,000, subject to successful technical milestones and budgetary compliance. Financial administration requires registration and invoice submission via the Payment Management Services (PMS) portal, with detailed justifications for each payment tied to specific milestones or TDD tasks, and salary support for individuals is capped at the Executive Level II rate set by the Office of Personnel Management. All awarded work must occur in the United States, with priority given to domestic entities, and proposers must confirm compliance with national security
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 2 months ago

DEADLINE

in 6 months
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