This Pre-Solicitation opportunity from Department Of Defense was posted on September 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Sole Source Bioconscientia
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
Active Opportunities Like This One
AI Contract Overview
The US Army Corps of Engineers Engineer Research and Development Center is seeking advanced research and development support to advance synthetic biology tools focused on environmental sensing, sustainable biomanufacturing, and critical material supply chain security. The scope of work includes the development of synthetic cell systems for physical and chemical stimuli sensing, molecular engineering of CO2-utilizing yeast via AI-optimized Rubisco variants, the design of protein chromatography platforms for Rare Earth Element capture, and the creation of genetically encoded conductive protein nanowires for bio-electronic sensing. Optional projects may also cover bio-functionalized carbon quantum dot sensing and microbiologically induced calcite precipitation for geotechnical use. The government intends to award this firm-fixed-price contract as a sole source to Bioconscientia, LLC under the authority of RFO 6.103-1, citing the company's unique proprietary knowledge and specialized capabilities in AI-driven protein engineering and high-throughput automated bioprocessing. This procurement, identified by solicitation number W912HZ26QA049 and NAICS code 541714, is managed by the Department of Defense in Vicksburg, Mississippi. The justification for the sole source award is based on the contractor's ability to meet stringent technical objectives and timelines without unacceptable delays or duplication of costs.
General Info
Place of Performance
MS, 39180, USASet-Aside
Documents
1AI Contract Breakdown
Uniform Contract FormatContract not broken down yet
CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.
Timeline
Submission Closed
Organization & Contact Information
Full Description
Presolicitation and Notice of Intent to Sole Source
The US Army Corps of Engineers, Engineer Research and Development Center (ERDC) ERDC-EL Biotechnology Team requires advanced R&D support to investigate and advance synthetic biology tools. The overall objective is to develop, optimize, and
validate platforms that address environmental sensing, critical material supply chain security, and sustainable biomanufacturing. The required tasks encompass:
- Project A: Development of synthetic cell systems for sensing physical and chemical stimuli via two-component signaling (TCS).
- Project B: Molecular engineering of CO2-utilizing yeast via AI-optimized Rubisco variants for austere biomanufacturing.
- Project C: Design and testing of engineered protein chromatography platforms for selective capture of Rare Earth Elements (REE).
- Project D: Development of genetically encoded conductive protein nanowires for bio-electronic sensing and energy assimilation.
- Optional Projects E & F: Bio-functionalized carbon quantum dot sensing platforms (including biodefense surrogates) and microbiologically induced calcite precipitation for geotechnical applications.
Bioconscientia, LLC possesses highly specialized, unique capabilities and proprietary institutional knowledge essential to executing this complex portfolio of synthetic biology research. The successful execution of this work requires an integrated research environment capable of combining artificial intelligence (AI)-driven protein engineering, high-throughput automated bioprocessing, and cell-free expression systems. Specifically, the contractor must have immediate, proven expertise in:
- Engineering UV-B-responsive genetic circuits and complex two-component systems (TCS).
- Developing AI-guided Rubisco variants and scaling up automated fermentation.
- Pioneering affinity-based separation platforms specifically targeted at REE recovery from e-waste and processed magnets.
- Advanced bio-electronic material fabrication (e.g., genetically encoded conductive protein nanowires and carbon quantum dot functionalization).
No other source possesses the synergistic combination of specialized personnel, advanced laboratory infrastructure, and concurrent expertise across these disparate domains (biological CO2 assimilation, bio-electronics, and REE chromatography) required to meet the Government's stringent timelines and technical objectives without unacceptable delays or duplication of cost.
The Government intends to procure from only one source under the authority RFO 6.103-1 Only One Responsible Source and No Other Supplies or Services Will Satisfy Agency Requirements. This Notice of Intent is for information purposes only. This is not a request for quote. A solicitation will not be issued. All responsible sources may submit a capability statement to CHL-CT-Quotes@usace.army.mil, Subject Line "Sole Source Bioconsciencia" not later than the date indicated in this notice. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Verbal responses are not acceptable.
More opportunities from Department Of Defense → W2R2 USA Engr R & D Ctr
Same awarding agency
Find Active Opportunities Like This
Get AI-powered intelligence on the opportunities still open
Every page of the solicitation package shredded into a compliance breakdown
AI-powered matching based on your capabilities and past performance
Competitor and incumbent history on the requirement
Automated alerts on amendments, Q&A deadlines, and award
Join 750+ contractors already using CLEATUS
