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This Pre-Solicitation opportunity from Department Of Defense was posted on September 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Sole Source Bioconscientia

Awarded
W912HZ26QA049Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714
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AI Contract Overview

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The US Army Corps of Engineers Engineer Research and Development Center is seeking advanced research and development support to advance synthetic biology tools focused on environmental sensing, sustainable biomanufacturing, and critical material supply chain security. The scope of work includes the development of synthetic cell systems for physical and chemical stimuli sensing, molecular engineering of CO2-utilizing yeast via AI-optimized Rubisco variants, the design of protein chromatography platforms for Rare Earth Element capture, and the creation of genetically encoded conductive protein nanowires for bio-electronic sensing. Optional projects may also cover bio-functionalized carbon quantum dot sensing and microbiologically induced calcite precipitation for geotechnical use. The government intends to award this firm-fixed-price contract as a sole source to Bioconscientia, LLC under the authority of RFO 6.103-1, citing the company's unique proprietary knowledge and specialized capabilities in AI-driven protein engineering and high-throughput automated bioprocessing. This procurement, identified by solicitation number W912HZ26QA049 and NAICS code 541714, is managed by the Department of Defense in Vicksburg, Mississippi. The justification for the sole source award is based on the contractor's ability to meet stringent technical objectives and timelines without unacceptable delays or duplication of costs.

General Info

Sole source contract for Bioconscientia, LLC to provide advanced synthetic biology research support.

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

MS, 39180, USA

Set-Aside

NONE

Documents

1

ERDC 26-3639 Restriction of Competition MFR - Bioconscientia, LLC

PDF, Low priorityjustification-and-authorization
Low

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Timeline

PhaseAwarded
Posted

Presolicitation

Awarded

Contract was awarded

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Defense → W2R2 USA Engr R & D Ctr
Contacts2 people available
OfficeVICKSBURG, MS, 39180-6199, USA
Office AddressVICKSBURG, MS, 39180-6199, USA
Contacts
Christine Shuck

Full Description

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Presolicitation and Notice of Intent to Sole Source


The US Army Corps of Engineers, Engineer Research and Development Center (ERDC) ERDC-EL Biotechnology Team requires advanced R&D support to investigate and advance synthetic biology tools. The overall objective is to develop, optimize, and
validate platforms that address environmental sensing, critical material supply chain security, and sustainable biomanufacturing. The required tasks encompass:


  • Project A: Development of synthetic cell systems for sensing physical and chemical stimuli via two-component signaling (TCS).
  • Project B: Molecular engineering of CO2-utilizing yeast via AI-optimized Rubisco variants for austere biomanufacturing.
  • Project C: Design and testing of engineered protein chromatography platforms for selective capture of Rare Earth Elements (REE).
  • Project D: Development of genetically encoded conductive protein nanowires for bio-electronic sensing and energy assimilation.
  • Optional Projects E & F: Bio-functionalized carbon quantum dot sensing platforms (including biodefense surrogates) and microbiologically induced calcite precipitation for geotechnical applications.

Bioconscientia, LLC possesses highly specialized, unique capabilities and proprietary institutional knowledge essential to executing this complex portfolio of synthetic biology research. The successful execution of this work requires an integrated research environment capable of combining artificial intelligence (AI)-driven protein engineering, high-throughput automated bioprocessing, and cell-free expression systems. Specifically, the contractor must have immediate, proven expertise in: 


  • Engineering UV-B-responsive genetic circuits and complex two-component systems (TCS).
  • Developing AI-guided Rubisco variants and scaling up automated fermentation.
  • Pioneering affinity-based separation platforms specifically targeted at REE recovery from e-waste and processed magnets.
  • Advanced bio-electronic material fabrication (e.g., genetically encoded conductive protein nanowires and carbon quantum dot functionalization).

No other source possesses the synergistic combination of specialized personnel, advanced laboratory infrastructure, and concurrent expertise across these disparate domains (biological CO2 assimilation, bio-electronics, and REE chromatography) required to meet the Government's stringent timelines and technical objectives without unacceptable delays or duplication of cost. 


The Government intends to procure from only one source under the authority RFO 6.103-1 Only One Responsible Source and No Other Supplies or Services Will Satisfy Agency Requirements. This Notice of Intent is for information purposes only. This is not a request for quote. A solicitation will not be issued. All responsible sources may submit a capability statement to CHL-CT-Quotes@usace.army.mil, Subject Line "Sole Source Bioconsciencia" not later than the date indicated in this notice. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Verbal responses are not acceptable.

More opportunities from Department Of Defense → W2R2 USA Engr R & D Ctr

Same awarding agency

NAICS: 541519
Federal
Information Technology Laboratory Commercial Solutions Openings (CSO)
Solicitation # W912HZ26SC006
The Engineer Research and Development Center’s Information Technology Laboratory is soliciting innovative products, services, and technologies through a Commercial Solutions Opening authorized under 10 U.S.C. 3458, treating all submissions as commercial items regardless of whether they are commercially available. This open-continuous solicitation, active for one year from May 20, 2026, targets areas including integrated digital transformation, advanced computing, secure and resilient systems, and data-driven decision-making to support defense and civil works missions. Solutions may include existing but underutilized technologies that enhance mission capabilities, and while no specific funding is guaranteed at the time of submission, individual program requirements posted under this CSO will outline desired outcomes, funding profiles, and deadlines. All awards will be firm-fixed price, and the government reserves the right to use commercial procedures under FAR Part 12 or other appropriate FAR parts, including potential prototype agreements under 10 U.S.C. 2371b. Participants from universities and non-profits must recognize that commercial contract clauses will apply and should consult legal counsel before submitting. Submissions must be made exclusively through the ERDCWERX platform, with the solicitation number W912HZ26SC006 and a response deadline of October 30, 2027. The NAICS code is 541519, and the office is located in Vicksburg, Mississippi. Proposals will be evaluated by ERDC and federal peer experts based on innovation and alignment with mission needs, with no set-aside for small businesses or specific categories. The point of contact for inquiries is Christy Love, and all details including submission guidelines are available at the ERDCWERX website. The procurement is conducted on a full and open basis, welcoming proposals from any eligible entity, with no distinction made between commercial and non-commercial entities in terms of eligibility, though contractual terms will be rooted in commercial practices.
Other Computer Related Services

POSTED

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DEADLINE

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