Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use
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This contract aims to enhance services that prevent infectious disease outcomes linked to drug use in high-impact settings serving people who use drugs by implementing two interconnected components. The first component focuses on strengthening data collection through biennial surveys of service settings to evaluate capacity, needs, access, and gaps in care, while also gathering biobehavioral data directly from people who use drugs to track trends in infectious disease testing, treatment, and prevention. The second component is designed to expand the availability and utilization of critical services including testing and treatment for hepatitis B, hepatitis C, and HIV within these settings. Applicants may choose to apply for one or both components, with the goal of building a more responsive national and local infrastructure informed by timely, accurate data. Expected outcomes include improved capacity to use data to guide public health interventions, higher rates of testing for hepatitis B, hepatitis C, and HIV among people who use drugs, increased initiation of hepatitis C treatment, and greater engagement in HIV care and treatment. The initiative aligns with CDC priorities and is administered by the Centers for Disease Control and Prevention’s National Center for HIV, Viral Hepatitis, STD, and TB Prevention under the Department of Health and Human Services. The posting date is July 24, 2026, with point of contact information provided for inquiries, and no set-aside or NAICS code has been specified. The funding opportunity is open to applicants prepared to operate in high-impact areas with significant drug use and infectious disease burdens.
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Full Description
This NOFO aims to strengthen services to prevent the infectious disease consequences of drug use in high impact settings serving people who use drugs (PWUD) through two components. Component 1 will improve service data by conducting a biennial survey of high-impact settings that serve PWUD to document capacity, needs, access, and service gaps. It will also improve timely local data on infectious disease consequences of drug use and the use of infectious disease testing, treatment, and prevention services at high-impact settings through a biennial biobehavioral survey of PWUD. Component 2 will increase support the availability and use of infectious disease testing, treatment and prevention services in high-impact settings serving PWUD. Applicants may apply for Component 1, Component 2, or both. Expected outcomes include enhanced capacity nationally and locally to use data to improve infectious disease testing, treatment and prevention services among PWUD, increased PWUD testing for HBV, HCV, and HIV, increased PWUD with hepatitis C who initiated treatment, and increased PWUD with HIV who engaged in care and treatment. This NOFO is in alignment with CDC priorities.
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