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This Solicitation opportunity from Government of Canada was posted on May 15, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Supply Of Flow Cytometer For High-Throughput Engineering Of Prokaryote Genetic Circuits And Protein

Closed
DAL2026-20511072International

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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AI Contract Overview

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This contract seeks the supply of a flow cytometer to enable high-throughput characterization of fluorescent protein genes expressed through synthetic genetic circuits in prokaryotic hosts, as part of a broader initiative to engineer cooperative protein systems that characterize and override epigenetic modifications controlling gene expression. The project leverages a novel approach called protein systems engineering, which integrates computational protein design and synthetic biology to simplify complex molecular functions into programmable gene expression events, bridging scientific discovery with applied engineering. The goal is to advance understanding of epigenetic regulation by creating systems that can probe and manipulate these processes, with potential implications for understanding and treating diseases linked to dysregulated gene expression. The solicitation, issued by Dalhousie University under the Government of Canada, is formally titled “Supply Of Flow Cytometer For High-Throughput Engineering Of Prokaryote Genetic Circuits And Protein” and carries the solicitation number DAL2026-20511072. Proposals must be submitted by June 10, 2026, and the procurement falls under NAICS code 334510 for laboratory apparatus and equipment manufacturing. The primary point of contact is Lindsay MacDonald, Contracting Authority, reachable via [email hidden]. Tender documents and any amendments are available exclusively through the Nova Scotia Procurement Portal, and parties interested in submitting responses may need to register on or pay fees to third-party hosting platforms used for document access or submission.

General Info

Supply of flow cytometer for genetic circuit analysis, supporting protein systems engineering project.

Agency

Government of Canada → Dalhousie University

Place of Performance

CAN

Set-Aside

NONE

Documents

0

No documents available

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Timeline

PhaseClosed
Posted

Solicitation

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyGovernment of Canada → Dalhousie University
Contacts1 person available
OfficeN/A
Organization / Agency
Government of Canada → Dalhousie University
Office AddressN/A
Contacts
Lindsay MacDonaldContracting Authority

Full Description

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‘Gene expression’ is the biological process responsible for protein production from gene encoding DNA sequences. In living organisms, complex biochemical processes regulate gene expression. This includes ‘epigenetic modifications’ to DNA which control gene expression without altering their encoded instructions. Investigation of dysregulated gene expression events reveals an inextricable link between aberrant epigenetic modification and disease. However, the complex molecular factors governing epigenetic modification remain poorly understood. Inspired by the genome editing revolution, this project seeks to engineer systems of regulatory proteins that cooperatively function to both (1) characterize and (2) override epigenetic modification processes in living organisms. To accomplish this objective, the conventional protein engineering workflow will be reimagined into a novel strategy called 'protein systems engineering'. Protein systems engineering amalgamates approaches from computational protein design and synthetic biology to create a workflow for engineering proteins that operate in cooperation to achieve new functions. This is accomplished using ‘genetic circuitry’ to condense multiple complex protein functions into simplified gene expression events. Thus, this approach links the scientific discovery process to application driven engineering. Accordingly, this RFP seeks prospective proponents to submit proposals for the supply of a flow cytometer for high-throughput characterization of fluorescent protein genes delivered on genetic circuitry expressed in prokaryote hosts. Cost of acquiring documents: Not Applicable Terms of payment for acquiring documents: Not Applicable Tender notices on CanadaBuys published for Nova Scotia Public Sector Entities may not reflect amendments. For tender documents and up-to-date addenda, refer to the Nova Scotia Procurement Portal: https://procurement-portal.novascotia.ca/tenders/DAL2026-20511072 For additional detail on contract duration, refer to the tender documents. Note that in some cases, third-party hosting platform registration and/or fees may be required to review related documents, or to submit tender responses.

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