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The Genesis Mission: Transforming Science and Energy with AI

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DE-FOA-0003612Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The Genesis Mission, solicitation DE-FOA-0003612, is a national initiative led by the U.S. Department of Energy and the White House Office of Science and Technology Policy to establish the American Science and Security Platform. The program seeks interdisciplinary teams to develop self-improving artificial intelligence models and integrated scientific workflows to accelerate breakthroughs in energy dominance, discovery science, and national security. Funding is available for Phase I small teams with a nine-month performance period and Phase II large teams with a three-year period. The initiative targets several key focus areas, including advanced manufacturing, biotechnology, critical materials, nuclear fission and fusion, quantum information science, semiconductors, and microelectronics. Total anticipated funding for the program is 293.76 million dollars. This procurement is conducted as an Other Transaction Agreement, utilizing a structure of funding agreements based on milestones or reimbursement rather than standard FAR clauses. Awards are determined through a merit review process, risk assessments, and program policy factors, with a specific emphasis on commercialization potential for applied technology. Applicants must maintain active registration in SAM.gov and provide a Unique Entity Identifier. Performance is managed through specific technical objectives and milestones, with payments processed via the Department of Treasury's ASAP system. All proposed research must be publishable in scholarly literature and must comply with strict security regulations, including the prohibition of restricted data and unclassified controlled nuclear information.

General Info

DOE Genesis Mission funds AI for energy, science, and security via OTA agreements.

Documents

5

DOE Genesis Mission RFA DE-FOA-0003612 Amendment 000003

PDF, High priority: read this firstamendment
High

Genesis Mission Phase I Application Template v2

XLSX, High priority: read this firstapplication-template
High

Genesis Mission Phase II Application Template

XLSX, High priority: read this firstapplication-template
High

Sample Other Transaction Agreements for DE-FOA-0003612 - Genesis Mission

PDF, High priority: read this firstcontract-document
High

Genesis Mission Phase II LOI Template v2

XLSX, Low priorityother
Low

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Organization & Contact Information

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AgencyDepartment Of Energy - Office Of Science
Contacts1 person available
OfficeUSA
Office AddressUSA
Contacts
Michael S ZarkinGrants Management Specialist

Full Description

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The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.

 

DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).

 

In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards. In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications.

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