The Genesis Mission: Transforming Science and Energy with AI
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The Department of Energy's Office of Science, along with several of its specialized offices, is seeking applications from interdisciplinary teams to address the Genesis Mission National Science and Technology Challenges. The goal is to harness novel artificial intelligence models and frameworks to accelerate scientific discovery and improve research and development workflows related to energy, environmental, and nuclear challenges. Teams are encouraged to integrate resources from DOE, the National Nuclear Security Administration, National Laboratories, U.S. industry, and academia to develop AI models that could potentially be incorporated into the American Science Cloud, thereby advancing national security and prosperity. For Fiscal Year 2026, the solicitation invites both Phase I small team and Phase II large team proposals across a broad range of focus areas, including advanced manufacturing, biotechnology, critical materials, nuclear fission and fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy. Those awarded Phase I funding will have an opportunity to apply for Phase II awards under this or an amended solicitation planned to be issued soon. Additionally, DOE intends to update the solicitation or issue a new funding opportunity in Fiscal Year 2027 to continue supporting these research efforts through another round of Phase I and Phase II applications. The deadline for responses is December 17, 2026, and further details are available via the Department of Energy’s grants portal.
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Full Description
The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.
DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).
In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards. In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications.
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