DIAGENODE, LLC

Diagenode, LLC specializes in the manufacturing and support of advanced analytical laboratory instrumentation for epigenetic and genomic research, with deep expertise in sonication-based DNA fragmentation systems such as the Bioruptor Pico and Megaruptor platforms. The company delivers precision hardware solutions and associated maintenance services critical for high-molecular-weight DNA library preparation, enabling next-generation sequencing on platforms like PacBio and Oxford Nanopore. Complementing its instrumentation focus, Diagenode provides specialized testing and biological sample preparation services, particularly in DNA methylation analysis using Illumina Infinium Methylation Epic and Mouse arrays, supporting epigenetics research across environmental, agricultural, and biomedical domains. Their technical differentiation lies in end-to-end support for chromatin immunoprecipitation and methylation profiling workflows, bridging instrument performance with downstream genomic analysis needs. Diagenode maintains strong, recurring relationships with the Environmental Protection Agency, Department of Agriculture, and Department of Health and Human Services. For EPA, they deliver methylation array testing and environmental epigenomics support; for USDA, they provide sonication instrumentation and transcription factor ChIP-seq research services; and for HHS, they supply critical genomic tools for human genome sequencing and biological sample processing, demonstrating consistent alignment with federal research priorities in environmental health and precision biology. The company’s primary industry focus is analytical laboratory instrument manufacturing and testing laboratories, positioning it at the intersection of biotech R&D and molecular diagnostics. Diagenode serves the growing demand for high-throughput, reproducible sample preparation in epigenomics, with specialization in DNA shearing, methylation profiling, and chromatin analysis—key enablers for large-scale genomic studies in public health and environmental science. Diagenode, LLC is a small business headquartered in Denville, New Jersey, with no federal certifications on record. Its geographic presence and operational focus are centered on supporting federal research missions through targeted instrumentation and laboratory services, establishing a niche role in the federal life sciences supply chain.