This Combined Synopsis/Solicitation opportunity from Department Of Veterans Affairs was posted on September 26, 2024. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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AN12--DNA Methylation & Genome Wide Association assays for evaluating changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Program

Awarded

36C24E24Q0139Federal

Submission Closed09/27/2024, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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AI Contract Overview

This contract pertains to the provision of DNA methylation and genome-wide association (GWAS) assays aimed at evaluating changes in epigenetic aging among Veterans with HIV participating in a telehealth-delivered high-intensity exercise program, under the Department of Veterans Affairs. The solicitation, numbered 36C24E24Q0139, is a new effort with no incumbent service provider, and it is managed by the VA Portland Health Care System. The scope involves genotyping using standard arrays such as the MVP array or Illumina GSA, with samples processed as needed for the assays, and the results to be returned to the VA after completion. Data delivery must be encrypted and transmitted via secure FTP, with no additional data analysis required beyond providing raw data. The project involves analyzing a subset of 102 samples from a total of 191, with the primary focus on genotyping for GWAS purposes. The contract emphasizes the use of standard genotyping arrays rather than long-read sequencing technologies like PacBio. Samples are to be returned to the VA once assays are completed, and the process is designed to be straightforward, with the contractor responsible solely for sample processing and data transfer, without conducting further data analysis. The solicitation was posted on September 26, 2024, with responses due by September 27, 2024, and the primary point of contact is Contract Specialist Karly Gabrysiak.

General Info

Epigenetic Aging analysis for Veterans with HIV, utilizing GWAS and EPIC V2 array.

Agency

Department Of Veterans Affairs → Rpo East (36C24E)

Contract Value

$66,869

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

PA, USA

Set-Aside

NONE

Awardee

TEMPUS AI, INC

Award Issued Date

09/30/2024, 12:00:00 AM UTC

Documents

Amendment 1 - Solicitation 36C24E24Q0139 (DNA Methylation & GWAS Assays)

amendment

High

Solicitation 36C24E24Q0139 - DNA Methylation & GWAS Assays

rfq

High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

1 update

PhaseAwarded

PostedSep 24

Combined Synopsis

Notice updatedSep 26

The notice title changed. The notice description changed.

AwardedSep 30

Contract was awarded

Submission Closed

09/27/2024, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Veterans Affairs → Rpo East (36C24E)

Contacts1 person available

OfficePITTSBURGH, PA, 15212, USA

Organization / AgencyDepartment Of Veterans Affairs → Rpo East (36C24E)

Office AddressPITTSBURGH, PA, 15212, USA

Contacts

Karly GabrysiakContract Specialist

contact@example.gov

Full Description

Amendment 1 Answer Vendor Questions for Solicitation 36C24E24Q0139. Question 1: We are performing independent research on the Combined Synopsis/Solicitation (36C24E24Q0139). We would like to know if this is a brand new contract OR if there is (was) an incumbent performing these services. If not brand new, could you please provide the current / previous contract number? Appreciate any insight you can provide. Answer to Question 1: This is new and there is no incumbent performing these services for the Requesting Activity for VA Portland Health Care System. Questions 2-8 were sent in together* Question 2: We utilize a custom EPIC V2 array with additional information. Would that array be appropriate to use for this project or would the standard EPIC V2 array be more appropriate? Answer to Question 2: The standard version of EPIC V2 array is what is planned for use. Question 3: Are the 102 samples to be used for GWAS a subset of the 191 or a separate cohort? In either case, can you help me better understand the expectation for sample processing in Item Number 4? Answer to Question 3: The 102 is a subset of the 191. The sample processing is any required processing to do the required assays only. Question 4: Is there an expectation to use genotyping arrays for the GWAS? If so, is there a preference or would one of the arrays we use for MVP be appropriate? Answer to Question 4: The GWAS array genotyping is part of the study. The MVP array is fine, as well as the Illumina GSA array. Question 5: Would PacBio long read sequencing be considered for the GWAS? Answer to Question 5: No, only the GWAS array for genotyping. See (3) above. Question 6: What should be the disposition of the samples once the assays are finished? Answer to Question 6: If possible, would be best to return to us. Question 7: Is there an expectation for data analysis beyond providing the raw data? Answer to Question 7: No data analysis needed. Question 8: What are the requirements for data delivery? Answer Question 8: Encrypted and sent via secure FTP. Upon award this will be facilitated.