This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on February 21, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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ARPA-H Rare Disease AI/ML and Precision Integrated Diagnostics (RAPID) Patients’ Day

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ARPA-H-SN-25-127Federal

Submission Closed02/21/2025, 05:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

Federal

Prototyping & Pilot Project ExecutionThis subcontract focuses on the prototyping and pilot project execution of innovative construction and delivery capabilities for prime contractors supporting Department of the Air Force 36 CONS projects. Operating under an Other Transaction Agreement framework, the scope of work involves implementing agile construction methods and testing emerging building technologies to deliver functional prototype or pilot-scale facilities. Managed by the Department of Defense agency FA5240 36 Cons Lgc, the project is categorized under NAICS code 541715. The primary objective is to advance construction capabilities through the practical application and testing of new technologies within a specialized military infrastructure context.

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Nanotechnology Research Support & Specialized Lab Services

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Space Domain Awareness (SDA) Software and AnalyticsThis subcontract focuses on the development of Space Domain Awareness software and analytics to support prime contractors on NCIA Space Domain Operational Functions projects. The scope of work involves creating software capable of acquiring and correlating orbital and environmental data to facilitate object identification, tracking, behavior characterization, conjunction analysis, and orbital predictions. The project utilizes orbital object catalogues and fragmentation analysis tools to deliver a fully operational software suite and a maintained Recognised Space Picture. The contract is managed under the Department of Commerce Bureau of Industry and Security, with performance taking place in Belgium. Due to the sensitive nature of the orbital data and operational functions, personnel are required to hold high-level NATO or National security clearances. Interested parties must respond by December 3, 2026.

Bureau Of Industry And Security

POSTED

DEADLINE

Synthesis and Distribution of Drugs of Abuse and Related Compounds

Solicitation # 75N98027R00006OT

National Institutes Of Health Nida

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Synthesis and Distribution of Drugs of Abuse and Related Compounds

Solicitation # 75N98027R00006SB

National Institutes Of Health Nida

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Bolstering Underutilized Industry by Leveraging Technology Transfer (BUILTT) pilot program

Solicitation # 10292026-LR-27

The Department of Energy, in partnership with the National Nuclear Security Administration, has announced the Bolstering Underutilized Industry by Leveraging Technology Transfer (BUILTT) pilot program. This initiative, conducted by the Nevada National Security Sites, Y-12 National Security Complex, and Kansas City National Security Campus, aims to assist qualified U.S. small and medium-sized businesses in manufacturing low-volume, high-impact technologies developed by DOE/NNSA Labs, Plants, and Sites. These technologies, which include specialized optical imaging, radiation and chemical sensing systems, precision electrical components, and advanced materials, often have limited commercial markets but are critical for government mission requirements. Under the program, selected businesses may receive a Cost Reduction License (CRL) for a nominal fee, granting them the rights to produce specified technologies for sale to the DOE, NNSA, and other government customers at pre-negotiated prices. Eligibility is limited to U.S.-based SMBs, with preference given to those near participating sites or those with SBA 8(a) or HUBZone designations. Interested parties are evaluated based on their technical and manufacturing capabilities, financial capacity, and ability to meet regulatory and security requirements. Responses must be submitted to the Technology Partnerships and Intellectual Property Office by April 1, 2027, and are categorized under NAICS code 541715.

Msts – DOE Contractor

POSTED

DEADLINE

ARTIFICIAL INTELLIGENCE AND NEXT GENERATION DISTRIBUTED COMMAND AND CONTROL

Solicitation # FA875023S7006

The Department of the Air Force, Air Force Materiel Command, AFRL Rome Research Site, is soliciting research and development for Artificial Intelligence and Next Generation Distributed Command and Control under BAA FA8750-23-S-7006. The primary objective is to transform Joint Force Command and Control capabilities by leveraging AI to enhance battlespace assessment, plan selection, and force monitoring in distributed and contested environments. A significant focus is placed on the Battle Management of AI, which seeks technologies to monitor, adapt, and deploy AI capabilities during mission execution to counter model drift and ensure operational safety. This is an open, two-step BAA effective until August 30, 2028, with total estimated funding of approximately $99 million. Individual awards typically range from $200,000 to $20 million and may be awarded as FAR-based procurement contracts, grants, cooperative agreements, or Other Transactions. Initial submissions are limited to three-page white papers, with formal proposals accepted by invitation only. Evaluation is based on a trade-off process considering overall scientific and technical merit, related experience, solution maturity and openness, and cost realism. Prospective offerors must adhere to strict guidelines, including the Gold Standard Science principles for reproducibility and transparency, and must disclose any potential Organizational Conflicts of Interest. Submissions require a CAGE code, unique entity identifier, and an approved DD Form 2345. The government may provide Government Furnished Software for specific technical areas, and all research must comply with National Industrial Security Program standards for the protection of classified information.

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Hubble Space Telescope (HST) Servicing

Solicitation # 80GSFC27RFIHSTS

NASA Goddard Space Flight Center

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Air Force Research Laboratory (AFRL) Enterprise Commercial Solutions Opening (CSO)

Solicitation # FA865226SC003

The Air Force Research Laboratory (AFRL) Enterprise Commercial Solutions Opening (CSO), solicitation FA8652-26-S-C003, is an overarching enterprise framework designed to acquire innovative commercial products and services. Issued under the authority of 10 USC 3458 and DFARS Subpart 212.70, the CSO establishes a structure for issuing competitive solicitations known as Spirals. These Spirals target a wide range of Areas of Interest (AOI) across the Air, Space, Cyberspace/Electronic Warfare, and Cross-Domain technology domains, including hypersonics, cybersecurity, quantum technologies, and human-machine teaming. Resulting awards may take the form of fixed-price FAR Part 12 contracts or Other Transactions for Prototype (OTP). Foreign participation is strictly prohibited. The acquisition process typically follows a two-step approach for Spirals. In Step One, offerors submit a Commercial Solutions Brief (CSB) consisting of a PowerPoint briefing and a white paper. Those categorized as Selectable are invited to Step Two to submit a full Commercial Solutions Proposal (CSP), which includes a technical proposal, a Statement of Work, and a price proposal with an editable Excel pricing model. Evaluation is conducted via subject-matter expert peer review, focusing on technical merit, applicability, importance to agency programs, and funding availability. Strict security and compliance requirements are in place, including mandatory security risk reviews for all senior and key personnel to mitigate foreign influence. Offerors must also perform an Organizational Conflict of Interest (OCI) analysis and adhere to DoD item unique identification standards (MIL-STD-130) for delivered hardware costing $5,000 or more. Contract administration, including invoicing and payment, is managed electronically through the Wide Area WorkFlow (WAWF) system.

Air Force Research Laboratory

POSTED

DEADLINE

Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Solicitation # ARPA-H-SOL-26-163

The Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) program, issued by the Advanced Research Projects Agency for Health (ARPA-H) under solicitation ARPA-H-SOL-26-163, aims to advance the understanding and treatment of autism by identifying evolving developmental trajectories across the lifespan. The program focuses on the nonlinear interactions between genetic, biological, behavioral, and environmental factors to move toward personalized intervention. The scope of work is divided into four Technical Areas: Multi-Factor Analysis and Trajectory Identification (TA1), Population-Scale Modeling and Data Integration (TA2), Precision Intervention and Trajectory Testing (TA3), and Technologies for Communication, Quality of Life, and Embedded Assessment (TA4). Key deliverables include an operating federated network with at least ten live nodes, open-license data standards, a versioned model registry, and the development of technologies that combine clinical assessment with tools to improve daily function and quality of life. Awards will be made via Other Transaction (OT) instruments to proposers determined to be the most advantageous to the government based on scientific merit, capabilities, price/value analysis, and relevance to the ARPA-H mission. The program utilizes a milestone-based acceptance process with gates at 12, 24, and 48 months. Technical requirements emphasize privacy-preserving linkage, differential privacy, and secure execution. Proposers must be registered in SAM.gov and are required to use specific templates for Solution Summaries, with staggered submission deadlines ranging from October 2026 through January 2027. ARPA-H prioritizes entities that will conduct the funded work within the United States.

Advanced Research Projects Agency For Health (arpa-H)

POSTED

DEADLINE

Japanese Research PartnershipThe Japanese Research Partnership is a subcontract managed by the National Research Foundation of Korea to provide specialized research and facility support for prime contractors involved in International Joint Research Rapid Support Project optical interconnect projects. The scope of work focuses on collaborative research and development of uLED and uOLED technologies, utilizing the infrastructure of a recognized Japanese research institution to conduct joint experimentation and deliver shared data, research findings, and prototype contributions. The project is categorized under NAICS code 541715, with the place of performance located in South Korea. Interested parties should note that the solicitation was posted on October 29, 2026, with a response deadline of November 11, 2026.

National Research Foundation of Korea

POSTED

DEADLINE

2026년도 국제공동연구 신속지원사업 신규과제 공모

Solicitation # 2026-1045

The 2026 International Joint Research Rapid Support Project, solicitation number 2026-1045, is a government-funded initiative managed by the National Research Foundation of Korea and the Ministry of Science and ICT. The project focuses on developing core original technologies for high-density parallel light sources, specifically micro-LED and micro-OLED, for use in AI data center optical interconnects. The total government support funding is 737.5 million KRW for a 16-month performance period running from December 2026 to March 2028. This project is classified as a National Strategic Technology in the semiconductors and next-generation OLED sectors, aiming to advance from Technology Readiness Level 3 to TRL 5. A mandatory requirement for this solicitation is the establishment of an international joint research network with Japanese research institutions to secure expertise in organic light-emitting materials and patents. Technical objectives include developing 32-channel arrays with specific performance targets: transmission speeds exceeding 1 GHz for micro-LED and 0.2 GHz for micro-OLED, and driving energy levels of 1 pJ/bit and 20 pJ/bit respectively. Final acceptance requires the submission of a functional prototype and verification through accredited certification bodies, official test reports, or witnessed self-evaluations. All research achievements and commercialization results must be managed through the Integrated Research Information System (IRIS), and the project is subject to technology fee collection and the 3-book 5-public rule for concurrent research limits.

National Research Foundation of Korea

POSTED

about 13 hours ago

DEADLINE

in 12 days

AI Contract Overview

The contract titled "ARPA-H Rare Disease AI/ML and Precision Integrated Diagnostics (RAPID) Patients’ Day" is a special notice issued by the National Institutes of Health under its advanced research arm, ARPA-H. Posted on February 21, 2025, the contract is identified by the solicitation number ARPA-H-SN-25-127 and falls under the NAICS code 541715, which pertains to research and development in the physical, engineering, and life sciences. The notice has been classified with the code AN13. This combined synopsis/solicitation is intended to engage and inform interested parties about an upcoming event or initiative rather than soliciting bids or proposals for a specific procurement. The response deadline coincides with the posting date, indicating that the notice's primary purpose is informational. The point of contact for any inquiries is through the RAPID Email Box at [email hidden]. This initiative aims to focus on the use of Artificial Intelligence/Machine Learning (AI/ML) and precision integrated diagnostics in the realm of rare diseases, underlining ARPA-H’s commitment to advancing healthcare technologies. The office managing this notice is located in Bethesda, Maryland, USA, and the project’s location of interest is within the United States. Although the document does not specify the type of set-aside, it is active and the details can be accessed through the provided website link to the federal contract opportunities platform at sam.gov. There is also a resource link for downloading additional materials related to this contract.