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Bioanalytical Assay Development and Quantification

Active
Federal

Contract Overview

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The contract requires the development and performance of liquid chromatography-tandem mass spectrometry assays to quantify plasma concentrations of three small-molecule inhibitors and their metabolite 1-MNA in mouse plasma samples. The work involves establishing validated methods for accurate and precise measurement of these compounds, ensuring reliability for preclinical pharmacokinetic studies. The assays must be capable of detecting low concentrations with appropriate sensitivity, specificity, and reproducibility across the expected concentration range in biological matrices. This subcontract is issued under the NAICS code 541380, indicating a focus on scientific and technical consulting services, and is associated with the National Institutes of Health under the Department of Health and Human Services. The solicitation was posted on August 7, 2026, with a response deadline of August 24, 2026. The place of performance and specific location details are not provided, and no set-aside provisions are specified. The work is intended to support biomedical research activities, likely aimed at evaluating drug metabolism and exposure profiles in mouse models.

General Info

Develop validated LC-MS/MS assays to quantify three inhibitors and 1-MNA in mouse plasma for pharmacokinetic studies.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541380 - Testing Laboratories and ServicesView NAICS

Place of Performance

MD

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
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Office AddressN/A
ContactsNo contact information available

Full Description

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Develop and perform LC-MS/MS assays to quantify plasma concentrations of three small-molecule inhibitors and their metabolite 1-MNA in mouse plasma samples.

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