Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, August 19 at 2:00 PM EDT

Register Free →
logo
Get CLEATUS

Developing selective small-molecule inhibitors of

Active
75N98026Q00986Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The National Institutes of Health, Office of the Director, Office of Acquisitions, is seeking proposals through a competitive combined synopsis and solicitation for the development of selective small-molecule inhibitors, issued under FAR Subpart 12.6 as a streamlined commercial acquisition not expected to exceed the simplified acquisition threshold. The solicitation number is 75N98026Q00986, with responses due by August 24, 2026, and the contract will be awarded on a firm-fixed-price basis to the offeror providing the best value to the government. This acquisition is unrestricted and intended for full and open competition, with the NAICS code 541715 indicating research and development in the physical, engineering, and life sciences, though the provided description references a different NAICS code which may reflect a discrepancy. The offering organization is located at 20892 Bethesda, MD, with John A. Johnston, Jr. as the primary point of contact via email and phone. The solicitation incorporates all Federal Acquisition Circular provisions and clauses effective August 7, 2026, and no separate written solicitation will be issued.

General Info

NIH seeks firm-fixed-price small-molecule inhibitors via open competition through August 24, 2026, NAICS 541715.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

MD

Set-Aside

NONE

Documents

(1)

Sol_75N98026Q00986.pdf

PDF

AI Contract Breakdown

Uniform Contract Format

What is UCF?

Uniform Contract Format (UCF) uses AI to break down any contract into standardized sections—scope, pricing, deliverables, and evaluation criteria.

Timeline

PhaseSolicitation
Posted

Solicitation

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
Contacts1 person available
OfficeBETHESDA, MD, 20892, USA
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
View Agency Profile
Office AddressBETHESDA, MD, 20892, USA
Contacts
JOHNSTON JADDUA C
contact@example.gov
+1 (555) 000-0000

Full Description

Show more
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

(ii) The solicitation number is 75N98026Q00986. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold (if applicable).

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a (Firm-Fixed-Price) to the offeror responsible whose proposal represents the best value to the Government.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular effective August 7, 2026

(iv) The associated NAICS code is 325414 Biological Product (except Diagnostic) Manufacturing and the small business size standard is 1250 Employees.

This requirement is unrestricted.

Similar Contracts

Same NAICS industry code

NAICS: 541715
New
Federal
Research & Development – Advanced Technology PrototypingThis contract pertains to advanced technology prototyping under a DARPA-managed research and development initiative, focusing on technical development that integrates systems engineering, algorithm design, and hardware-software co-design. It is structured as a subcontract with a multi-phase execution approach, requiring innovative solutions that push the boundaries of current capabilities in defense-related technologies. The work will involve iterative prototyping and demonstration of novel systems, with each phase building on the outcomes of the prior one to validate technical feasibility and operational relevance. The opportunity is open for responses until October 19, 2026, and is classified under NAICS code 541715 for research and development in the physical, engineering, and life sciences. Performance is expected to be conducted under the auspices of the Department of Defense, though specific location details are not defined. The contract is part of a broader effort to accelerate the transition of cutting-edge research into practical prototypes, with an emphasis on rapid development cycles and cross-disciplinary collaboration. Respondents must demonstrate expertise in high-risk, high-reward technology development aligned with DARPA’s strategic goals, and proposals are expected to address scalability, manufacturability, and potential for operational deployment.
Defense Advanced Research Projects Agcy

POSTED

about 19 hours ago

DEADLINE

in 2 months
View Details
NAICS: 541715
New
Federal
Regenerative Medicine for Tissue RepairThe contract titled Regenerative Medicine for Tissue Repair is a subcontract issued by the Defense Health Agency under the Department of Defense to advance research into regenerative therapies aimed at accelerating tissue repair in combat-related injuries. The focus is on innovative approaches such as stem cell applications and biomaterials designed to restore function and reduce recovery time for severe battlefield trauma. The opportunity was posted on August 7, 2026, with a response deadline of October 30, 2026, at 4:00 PM, providing potential applicants a limited window to submit proposals. The North American Industry Classification System code 541715 indicates this effort falls under research and development in the life sciences, specifically in the biomedical field. Performance of the work is expected to be conducted in Frederick, Maryland, aligning with existing military and medical research infrastructure in the region. This subcontract represents a strategic Department of Defense initiative to bridge cutting-edge medical science with urgent battlefield medical needs.
Defense Health Agency

POSTED

about 19 hours ago

DEADLINE

in 3 months
View Details
NAICS: 541715
New
Federal
Pathogen-Agnostic Sepsis CountermeasuresThe contract centers on the research and prototype development of pathogen-agnostic countermeasures for sepsis, targeting treatments or diagnostics effective against multiple infectious agents including Pseudomonas aeruginosa and Shigella. This initiative seeks to identify novel therapeutic or diagnostic platforms that function independently of the specific causative pathogen, addressing the critical challenge of sepsis management in heterogeneous infection scenarios. The work is funded under a subcontract arrangement by the Defense Health Agency within the Department of Defense, reflecting a strategic focus on advancing military and civilian medical readiness through innovative biomedical solutions. The project is tied to NAICS code 541715, categorizing it under research and development in the physical, engineering, and life sciences. The opportunity was posted on August 7, 2026, with a response deadline of October 30, 2026, and the performance location is designated as Frederick. While no set-aside provisions or point of contact details are provided, the emphasis on broad-spectrum effectiveness underscores the need for scalable, broadly applicable technologies that can rapidly respond to complex, multi-pathogen sepsis cases. The contract aims to accelerate the transition from concept to prototype, prioritizing solutions with the potential for immediate deployment in clinical and operational settings.
Defense Health Agency

POSTED

about 19 hours ago

DEADLINE

in 3 months
View Details
NAICS: 541715
New
Federal
Rat PK for the DYT1 lead compound
Solicitation # 75N98026Q00987
The National Institutes of Health, Office of the Director, Office of Acquisitions, is soliciting proposals under solicitation number 75N98026Q00987 for research and development services related to rat pharmacokinetics for the DYT1 lead compound. This is a competitive combined synopsis and solicitation issued under FAR Subpart 12.6 for commercial items, utilizing full and open competition without a separate written solicitation. The contract will be awarded on a firm-fixed-price basis to the offeror providing the best value to the government, with no set-aside designated and the requirement remaining unrestricted. The North American Industry Classification System code is 541715, with a small business size standard of 1,000 employees, and the solicitation is conducted under the streamlined procedures authorized by FAR 12.603, not expected to exceed the simplified acquisition threshold. Proposals must be submitted by the deadline of August 24, 2026, and all terms and conditions are governed by the Federal Acquisition Circular effective August 7, 2026. The work is to be performed in support of the NIH in Bethesda, Maryland, with primary point of contact being John Johnston, reachable via email at jaddua.johnston@nih.gov. This acquisition is not tied to any specific location beyond the agency’s office in Bethesda and is intended to procure commercial services in the field of physical, engineering, and life sciences research, excluding nanotechnology and biotechnology. All interested parties must respond through the provided SAM.gov link and adhere to the submission requirements outlined in the solicitation document.
National Institutes Of Health Olao

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541715
New
Federal
Maximum Tolerated Dose (MTD) Evaluation of PIP4Kga
Solicitation # 75N98026Q00989
The National Institutes of Health, Office of the Director, Office of Acquisitions, is soliciting proposals under solicitation number 75N98026Q00989 for the Maximum Tolerated Dose (MTD) Evaluation of PIP4Kga, utilizing a commercial items acquisition process under FAR Subpart 12.6. This combined synopsis/solicitation is issued as a competitive, full and open opportunity using a firm-fixed-price contract structure, with no set-aside designated, and is not expected to exceed the simplified acquisition threshold. The requirement falls under NAICS code 541715 for Research and Development in the Physical, Engineering, and Life Sciences, with a small business size standard of 1,000 employees, and is unrestricted to all eligible offerors. Proposals must be submitted by the deadline of August 24, 2026, and the solicitation incorporates all applicable provisions and clauses in effect as of August 7, 2026. The NIH seeks the best value proposal from responsible vendors capable of delivering the required research and development services, which will involve evaluating the MTD of PIP4Kga through scientifically rigorous methodologies. The place of performance and specific technical requirements are not detailed in the public notice, but inquiries should be directed to the primary point of contact, Johnstons Johnston, at jaddua.johnston@nih.gov. The acquisition is being conducted under the streamlined procedures of FAR 12.603, eliminating the need for a separate written solicitation, and all responses must be submitted through the designated SAM.gov portal. The contract award will be made based on factors demonstrating overall value, including technical capability, past performance, and price competitiveness.
National Institutes Of Health Olao

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541715
New
Federal
Synthesis of compounds and intermediates
Solicitation # 75N98026Q00970
The National Institutes of Health, Office of the Director, Office of Acquisitions, is seeking proposals for the synthesis of compounds and intermediates under solicitation number 75N98026Q00970, issued as a combined synopsis and solicitation in accordance with FAR Subpart 12.6. This procurement is conducted under simplified procedures for commercial items, employing full and open competition without solicitation of small business set-asides, and is not anticipated to exceed the simplified acquisition threshold. The contract will be awarded on a firm-fixed-price basis to the offeror whose proposal provides the best value to the government, assessed on technical merit and cost-effectiveness. The requirement falls under NAICS code 541715 for research and development in the physical, engineering, and life sciences, with a small business size standard of 1,000 employees. Proposals must be submitted by the response deadline of August 24, 2026, and the solicitation incorporates all applicable Federal Acquisition Regulation clauses in effect as of August 7, 2026. The work is to be performed in Bethesda, Maryland, with all correspondence directed to the designated point of contact, Johnstons Jaddua C, via email or phone. This solicitation is not a request for a separate written document, as the announcement serves as the complete solicitation package under streamlined commercial procurement rules. Offerors are expected to respond directly through the SAM.gov portal using the provided link.
National Institutes Of Health Olao

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541715
New
Federal
NextSTEP-3 Appendix B: Moon Base Demonstrations
Solicitation # M2M-MSFC-0001
The solicitation for NextSTEP-3 Appendix B: Moon Base Demonstrations, issued under solicitation number 80MSFC26R0003 by NASA Marshall Space Flight Center, seeks industry-led demonstrations to advance the development of a permanent lunar base at the Moon’s South Pole, aligning with national space policy goals of sustained lunar presence and deep space exploration readiness. This initiative targets technology readiness levels 6 and above to bridge the gap between innovation and operational mission needs, with an emphasis on architectural studies, risk reduction, and capability maturation rather than hardware production. The procurement employs a two-step process: initial White Paper submissions followed by invited full proposals under a Multi-Award Task Order Contract (MATOC) structure, with all awards structured as Firm-Fixed-Price contracts featuring performance-based milestone payments. The solicitation operates under a dual-path approach, combining Directed-Topic Calls that address specific, evolving mission needs with Open-Topic Calls that invite broader, unanticipated innovations—though submissions duplicating Directed-Topic concepts will be deemed ineligible. Evaluation is based on a non-trade-off, best-value selection process where Technical Capability (including Capability and Past Performance) is weighted at 1,000 points and must meet minimum thresholds for eligibility, while Price is assessed solely for reasonableness and completeness and does not factor into ranking. Proposals must adhere to strict formatting rules, including page limits and submission as a single searchable PDF, with key personnel qualifications, organizational conflict of interest plans, and intellectual property disclosures required as attachments. All contractors must maintain active SAM.gov registration, submit required certifications and representations, and comply with NASA-specific clauses related to data rights, payments, changes, subcontracting, whistleblower protections, and safety and liability waivers. Performance will be conducted under the NASA FAR Supplement, with invoicing required through the NASA Shared Services Center and all delivery and inspection terms left intentionally unspecified, reinforcing the analytical nature of deliverables—reports, models, simulations, and feasibility studies—rather than physical products. The contracting office at Huntsville, Alabama, remains the point of contact, with questions directed to the designated Contracting Officer, and submissions must be completed by the stated deadline to remain valid.
NASA Marshall Space Flight Center

POSTED

about 19 hours ago

DEADLINE

in 17 days
View Details
NAICS: 541715
New
Federal
MTEC Solicitation Summary: Fiscal Year 2026 Multi-Topic Request for Project Proposals
Solicitation # MTEC-26-04-MultiTopic
The Medical Technology Enterprise Consortium (MTEC) is soliciting innovative medical prototype solutions through its Fiscal Year 2026 Multi-Topic Request for Project Proposals, targeting critical gaps in military medical readiness across fourteen distinct Focus Areas. These areas span a broad spectrum of battlefield medical challenges, including prevention of infections from high-priority pathogens like Pseudomonas aeruginosa and Shigella, development of pathogen-agnostic sepsis countermeasures, reduction of barriers to mental health help-seeking, optimization of musculoskeletal injury treatment, advancement of non-addictive analgesics, and creation of sensor systems to monitor blast and blunt trauma exposure. Proposals must align strictly with one Focus Area and demonstrate clear military relevance, with solutions intended for use in austere or contested environments, supporting pre-hospital and early care stages (Roles 1 and 2). All submissions must be prototype-scale projects with a minimum Technology or Knowledge Readiness Level of 3, and must not have been previously submitted to MTEC within the last two years. Proposals are submitted via an Enhanced White Paper format as Stage 1 of a two-stage acquisition process, with selected candidates invited to submit detailed cost proposals in Stage 2. Funding is expected to range from $2 to $3.5 million per award over a 2 to 3-year performance period, contingent on available federal appropriations and technical merit. The solicitation encourages teaming among MTEC members to address complex technical requirements, and leverages a new member directory to facilitate collaboration. Proposals must adhere to the definition of a prototype under 10 U.S.C. § 4022 and may include medical devices, drugs, biologics, knowledge products, or novel delivery systems, but explicitly exclude vaccines, burn wound solutions, discovery-stage efforts, and IV-based interventions where specified. The deadline for Enhanced White Paper submissions is October 30, 2026, and successful projects may be eligible for non-competitive follow-on awards based on demonstrated progress and milestone achievement.
Defense Health Agency

POSTED

about 19 hours ago

DEADLINE

in 3 months
View Details
NAICS: 541715
New
Federal
Multi-Domain Force Applications and Traffic Management for Unmanned Aircraft Systems (M-FAT)
Solicitation # FA8750-25-S-7004
The Department of the Air Force, through the Air Force Research Laboratory’s Rome Research Site, is soliciting white papers under Broad Agency Announcement FA8750-25-S-7004 for research and development in Multi-Domain Force Applications and Traffic Management for Unmanned Aircraft Systems, with an open submission window until August 4, 2030. This two-step process invites initial white papers that must be no longer than four pages, double-spaced, and must include a technical summary, task objective, and proposed deliverables; formal proposals are accepted only by invitation after the initial review. The BAA targets advancements in electronic warfare, cyberspace operations, command and control automation, and low-collateral defeat technologies to counter small unmanned aircraft systems, particularly swarms, with emphasis on blurring the lines between cyber and electronic attack, integrating AI and machine learning for automated decision-making, and developing autonomous interceptors with integrated effects. Additional focus areas include enhancing sensor systems for detection and tracking, creating a cyberspace effects library, and advancing unmanned aircraft traffic management systems to safely integrate with existing air traffic infrastructure. Communication resilience is also sought through novel waveforms, networking protocols, and AI-driven spectrum management. Estimated funding totals approximately $499 million, with individual awards typically ranging from $500,000 to $20 million, though awards up to $99 million are possible. Multiple awards are anticipated, and the government may issue FAR-based contracts, grants, cooperative agreements, or Other Transactions, including prototype agreements with potential follow-on production pathways. Submission deadlines are recommended by fiscal year through 2029, with the final deadline set for August 4, 2030. Offerors must be registered in SAM, disclose organizational conflicts of interest, submit required security documentation including senior and key person profiles, and comply with NIST SP 800-171 cybersecurity baselines. Proposals are evaluated primarily on technical merit and mission alignment, with cost as a lesser factor, and must pass pre-award assessments for science and technology protection and financial responsibility under 2 CFR 200.206. All communications regarding technical matters must be directed to designated points of contact, and only contracting officers may commit the government. Submission noncompliance with formatting, content, or procedural instructions may result in rejection or reduced scores.
FA8750 Afrl Rik

POSTED

about 19 hours ago

DEADLINE

in almost 4 years
View Details
NAICS: 541715
New
Federal
REQUEST FOR INFORMATION: Solutions to Enhance US Rocket-Based Combined Cycle (RBCC) Propulsion Technologies
Solicitation # RFIFA930026R0001
This Request for Information (RFI) issued by the Air Force Research Laboratory’s Rocket and Space Propulsion Division seeks industry input to inform future development and demonstration efforts in Rocket-Based Combined Cycle (RBCC) propulsion technology, with a primary focus on Rotating Detonation Rocket Engines (RDRE) using storable, non-cryogenic propellants such as High Test Peroxide (HTP) combined with Rocket Propellant (RP) or Jet Fuel. The goal is to identify current capabilities, technology gaps, and viable pathways toward systems that minimize weight and logistics, maximize scalability and operational range, and enable flight demonstrations at relevant velocities and altitudes to achieve TRL-6. Key technical requirements include incorporating an RDRE as the primary combustor capable of ignition, throttling, and relight under flight conditions; utilizing thermal management systems for extended burn times; ensuring propellant compatibility with austere environments; and integrating a compact, scalable air inlet and flowpath that supports smooth mode transitions between rocket and air-breathing propulsion, with the air-breathing system providing primary thrust after acceleration. The RFI specifically excludes cryogenic propellants, turbine-based combined cycles, and systems requiring exotic materials or complex manufacturing. Respondents must provide written submissions not exceeding ten total pages in Microsoft Word using 11-point font, with administrative details—such as company name, NAICS business size, Cage Code/SAM UEI, organization address, and point of contact—excluded from the page limit. Responses are expected to address six core areas: overall RBCC system characteristics, state-of-the-art propulsion technologies requiring advancement, suitable storable propellants and their logistics and safety profiles, available ground and flight test facilities, computational modeling tools for design and analysis, and potential flight test platforms with estimated timelines and costs. All information submitted will be treated as market research and will not be used to select vendors for contract award, nor will the government compensate respondents for costs incurred. Proprietary information marked as such will be safeguarded in accordance with government regulations, though the government assumes no liability for improperly labeled proprietary data. Responses are due no later than August 10, 2026, and must be submitted electronically to the designated contracting officers. This RFI does not represent a commitment to issue a future solicitation, and any future contract opportunities will be announced on SAM.gov. Participation in this RFI does not guarantee eligibility for future procurements.
FA9300 Aftc Pzr

POSTED

about 19 hours ago

DEADLINE

in 4 days
View Details
NAICS: 541715
New
Federal
RFI for Next Generation Hypersonic Cruise Missiles
Solicitation # DARPA-SN-26-93
The U.S. Defense Advanced Research Projects Agency is seeking industry input through a Request for Information to shape the future acquisition strategy for a potential program focused on next-generation hypersonic cruise missiles. This RFI, issued under solicitation number DARPA-SN-26-93 and posted on August 7, 2026, with responses due by October 6, 2026, aims to refine technical specifications, validate programmatic assumptions, and guide the development of a competitive solicitation. The agency is particularly interested in fostering innovative partnerships between traditional defense contractors, non-traditional industry players, technology developers, and specialized test and evaluation providers to advance capabilities in this high-priority domain. Responses will directly inform DARPA’s understanding of current industry capabilities and potential pathways for innovation. The effort falls under NAICS code 541715, indicating a focus on research and development in the physical, engineering, and life sciences. All submissions must be directed to the TTO Acquisition Team at DARPA-SN-26-93@darpa.mil, and no set-aside status is anticipated, meaning the opportunity is open to all eligible entities regardless of size or status. The office is located in Arlington, Virginia, and while the place of performance has not been specified, the program is expected to involve nationwide collaboration and testing. This RFI serves as a precursor to a future formal solicitation, positioning industry to align its capabilities with DARPA’s strategic goals in hypersonic systems and to position itself for upcoming contract opportunities.
Defense Advanced Research Projects Agcy

POSTED

about 19 hours ago

DEADLINE

in about 2 months
View Details
NAICS: 541715
New
Federal
Developing selective small-molecule modulators of
Solicitation # 75N98026Q00988
The National Institutes of Health, Office of the Director, Office of Acquisitions, is seeking proposals for the development of selective small-molecule modulators through a competitive combined synopsis and solicitation issued under FAR Subpart 12.6. The solicitation, identified by number 75N98026Q00988, is open to full and open competition and intends to award a firm-fixed-price contract to the offeror providing the best value to the government. This acquisition is conducted under streamlined procedures for commercial products or services and does not exceed the simplified acquisition threshold. The requirement is unrestricted, with no set-aside provisions, and is classified under NAICS code 541715 for research and development in the physical, engineering, and life sciences, with a small business size standard of 1,000 employees. Proposals must be submitted by the deadline of August 24, 2026, and the solicitation incorporates all applicable provisions and clauses effective through the Federal Acquisition Circular dated August 7, 2026. The primary point of contact for inquiries is Johnston, Jaddua C, reachable via email at jaddua.johnston@nih.gov, with the performance location based in Bethesda, Maryland.
National Institutes Of Health Olao

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details

More opportunities from Department Of Health And Human Services → National Institutes Of Health Olao

Same awarding agency

NAICS: 518210
New
Federal
Data Management and Secure Delivery Platform
Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541690
New
Federal
Pharmacokinetic Data Analysis and Reporting
Other Scientific and Technical Consulting Services

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541380
New
Federal
Bioanalytical Testing and Quantitative Drug Analysis
Testing Laboratories and Services

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541940
New
Federal
In Vivo Pharmacokinetic (PK) Study Execution
Veterinary Services

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541611
New
Federal
Project Management and Technical ReportingThe contract entails end-to-end project coordination and comprehensive timeline oversight for a technical initiative under the National Institutes of Health, specifically managed through the Department of Health and Human Services. The contractor is responsible for delivering biweekly technical progress reports that detail synthesis status and provide forward-looking risk forecasts to ensure transparency and timely decision-making by NIH stakeholders. This subcontract is governed under NAICS code 541611, indicating it falls under management consulting services, and requires rigorous adherence to project milestones and reporting standards. The solicitation was posted on August 7, 2026, with responses due by August 24, 2026, and performance is expected to occur in an unspecified location under federal oversight without geographic restrictions noted.
Administrative Management and General Management Consulting Services

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 493190
New
Federal
Specialty Chemical Packaging and ShippingThe contract requires specialized packaging and shipping services for research-grade chemical compounds destined for the NIH/NCATS facility in Rockville, MD, with strict adherence to all federal labeling and transportation regulations governing hazardous and controlled research chemicals. All procedures must ensure the integrity and safety of the materials during transit, including proper containment, hazard communication, and documentation to meet DOT, OSHA, and other applicable standards. The work is structured as a subcontract under NAICS code 493190, which pertains to other transportation and support activities for warehousing and storage, indicating a focus on logistics expertise rather than manufacturing. The opportunity was posted on August 7, 2026, with a response deadline of August 24, 2026, and is issued under the Department of Health and Human Services through the National Institutes of Health Office of Acquisition and Logistics. Although specific contact and location details are not provided, performance is expected to support delivery to the Rockville, MD site, and contractors must demonstrate capability in handling regulated chemical shipments with precision and compliance.
Other Warehousing and Storage

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 541380
New
Federal
Analytical Testing and Certificate of Analysis (COA) ServicesThe contract involves providing analytical testing services for synthesized compounds to determine purity, confirm structural identity, and produce Certificates of Analysis to support the delivery of research compounds. The work is scoped to ensure rigorous quality control through established analytical methods that meet research-grade standards, with all results documented in formal COAs for regulatory and documentation compliance. Services are expected to be performed in alignment with industry best practices to enable reliable data generation for ongoing scientific investigations. This subcontract is issued under NAICS code 541380 and is associated with the National Institutes of Health under the Department of Health and Human Services. The solicitation was posted on August 7, 2026, with a response deadline of August 24, 2026. The place of performance and detailed contact information are not specified, but the work is intended to support internal research operations, and all deliverables must be completed within the timeframe and technical parameters required by the funding agency.
Testing Laboratories and Services

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 325412
New
Federal
Custom Organic Compound Synthesis (Non-GMP)The contract involves the custom synthesis of five small-molecule compounds, each in quantities of five grams, for use in Ewing sarcoma drug development under non-GMP research conditions. The work encompasses the full scope of organic synthesis including route design, multi-step chemical reactions, and purification to yield chemically defined products suitable for preclinical evaluation. All activities are non-GMP, meaning the compounds will not be produced under regulatory quality systems required for clinical use but rather for internal research and biological testing purposes. The effort is structured as a subcontract under the National Institutes of Health, operating through the Department of Health and Human Services, with the NAICS code 325412 indicating pharmaceutical and medicine manufacturing. The solicitation was posted on August 7, 2026, and responses are due by August 24, 2026, with no set-aside designation applied. The place of performance and point of contact details are not specified, and the work is expected to be carried out by an external research or synthesis provider aligned with the NIH’s oncology drug discovery goals.
Pharmaceutical Preparation Manufacturing

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details
NAICS: 513120
New
Federal
JOURNAL SUBMISSION AND WEB HOSTING – JOURNAL OF REPLICATION AND REPRODUCIBILITY
Solicitation # 75N98026Q00992
The solicitation number 75N98026Q00992 is a combined synopsis and request for quote under FAR Part 12 for journal submission and web hosting services related to the Journal of Replication and Reproducibility, issued by the National Institutes of Health through the Department of Health and Human Services. The acquisition is not set aside for small businesses and is open to any qualified commercial vendor. All relevant provisions and clauses are incorporated by reference and can be found on Acquisition.GOV, and vendors must review all attachments prior to submission. The deadline to submit intent to quote is August 14, 2026 at 5:00 PM ET, with questions or clarifications due by August 19, 2026 at the same time. Final quotations must be submitted no later than August 27, 2026 at 2:00 PM ET, though the system acceptance deadline is 6:00 PM ET. The contract will be performed in Bethesda, Maryland, with primary point of contact Jacob M. Balenson and secondary contact Shirley Ruiz-Lundgren available for inquiries through their respective NIH email addresses and phone numbers.
Periodical Publishers

POSTED

about 19 hours ago

DEADLINE

in 19 days
View Details
NAICS: 811210
New
Federal
Service and Maintenance Agreement for Bioraptr hig
Solicitation # 75N98026Q00974
The National Institutes of Health, Office of the Director, Office of Acquisitions, is seeking proposals under solicitation number 75N98026Q00974 for a firm-fixed-price contract to provide service and maintenance for the Bioraptr hig system. This acquisition is conducted under streamlined procedures for commercial items as outlined in FAR Subpart 12.6, with no separate written solicitation issued. The requirement is unrestricted, open to full and open competition, and is not expected to exceed the simplified acquisition threshold. The assigned NAICS code is 811210 for Electronic and Precision Equipment Repair and Maintenance, with a small business size standard of $34.0 million in annual receipts. Proposals must be submitted by August 24, 2026, and all provisions and clauses in effect as of the Federal Acquisition Circular dated August 7, 2026, apply. The contract will be awarded based on best value to the government, and the point of contact for inquiries is Johnsson, Jaddua C, reachable via email at jaddua.johnston@nih.gov. Performance is expected to occur in Bethesda, Maryland, with the agency office located at 20892, USA.
Electronic and Precision Equipment Repair and Maintenance

POSTED

about 19 hours ago

DEADLINE

in 16 days
View Details