Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, July 8 at 2:00 PM EDT

Register Free →
logo
Get CLEATUSFree Trial

Biomarkers of Cognitive Decline and Dementias of Aging in Individuals within the Autism Spectrum

Active
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The National Institute on Aging (NIA) plans to issue a Notice of Funding Opportunity (NOFO) inviting applications for observational studies on individuals with Autism Spectrum Disorders (ASD) across their lifespan. The primary objective is to investigate the prevalence and characteristics of age-related neurodegeneration, particularly Alzheimer's disease and related dementias, within the ASD population. The initiative aims to enhance understanding of how these neurodegenerative conditions manifest in individuals with ASD, with the ultimate goal of developing precision medicine approaches tailored to this understudied group. Proposed research should include deep phenotyping of aging adults on the autism spectrum and focus on the validation or discovery of biomarkers related to cognitive decline and dementia. This funding opportunity will employ the U01 cooperative agreement activity and emphasizes collaboration between autism experts and those specializing in aging and dementia research. It encourages partnerships between centers focused on neurodevelopmental disorders and those studying cognitive aging, fostering interdisciplinary approaches to address these complex questions. Although applications are not currently being accepted, this advance notice is intended to give potential applicants ample time to form collaborations and prepare responsive proposals. Dr. Alessandra Rovescalli of the NIA is the designated point of contact for inquiries related to this funding opportunity.

General Info

NIA invites U01 applications for ASD aging studies focusing on neurodegeneration and dementia biomarkers.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

Posted

forecast

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Alessandra Rovescalli Ph.D. National Institute on Aging (NIA
contact@example.gov
+1 (555) 000-0000

Full Description

Show more

The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to invite applications to conduct observational studies in individuals living with Autism Spectrum Disorders (ASD) along the lifespan. The overarching goal is to determine the occurrence of age-related neurodegeneration across the heterogeneities of the ASD spectrum, characterize the physiopathology and manifestation of Alzheimer's disease (AD) and AD-related dementias (ADRD) in ASD, and, ultimately, develop precision-medicine strategies tailored to this understudied population. It is expected that proposed studies pursue deep phenotyping of aging individuals across the ASD spectrum, along with the characterization/validation of existing biomarkers of age-related cognitive decline and/or dementia in this population, and/or the discovery of novel ones. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U01 activity code. This NOFO encourages collaborations between investigators with expertise in autism and those with expertise in aging and dementia, fostering interactions between established centers for neurodevelopmental research and centers studying age-related cognitive decline. 

Similar Contracts

NAICS: 541715
New
Federal
Consolidated Operations, Management, Engineering and Test (COMET) Follow-On ContractThe COMET Follow-On Contract supports a broad range of engineering, ground system development, spacecraft processing, and launch, landing, and recovery operations critical to NASA’s Exploration Systems Development programs including Exploration Ground Systems, the Space Launch System, and the Orion Multi-Purpose Crew Vehicle. It encompasses end-to-end capabilities for preparing and managing flight hardware at Kennedy Space Center, ensuring mission readiness for crewed and uncrewed deep space missions. The contract also extends its support to the International Space Station Program and the Launch Services Program, facilitating integrated operations across multiple high-priority NASA initiatives as well as commercial partnerships and collaborative ventures at the KSC facility. This contract is positioned as a forecast opportunity with a NAICS code of 541715, indicating its focus on research and development in the physical, engineering, and life sciences. Performance will occur at Kennedy Space Center, though the precise location is listed as TBD, reflecting the evolving nature of infrastructure planning. The Point of Contact for the opportunity is Nicholas Reinert, with Natalie Colvin serving as the Small Business Specialist, ensuring accessibility for diverse vendors. The contract is anticipated to be awarded following the posted forecast date of October 1, 2031, and will likely serve as a critical enabler for the next phase of U.S. space exploration activities involving sustainable lunar missions, deep space transit, and advanced ground infrastructure development.
Kennedy Space Center

POSTED

in over 5 years

DEADLINE

N/A
View Details
NAICS: 541715
New
Federal
FILMSS (Fully Integrated Lifecycle Mission Support Services) 3FILMSS 3 is a contract issued by NASA’s Ames Research Center to deliver comprehensive program, science, engineering, operations, and project management support across a broad spectrum of mission-critical initiatives. The contract encompasses biosciences flight development projects including mission implementation, instrument development, and technology advancement, as well as collaborative science programs such as astrobiology and virtual institutes. It also supports aeronautics research projects and various internal Ames offices, ensuring seamless integration of technical expertise and operational efficiency throughout the lifecycle of these efforts. Additionally, the contract provides specialized technical and professional services tailored to Ames Mission Support functions, enabling the center to advance its scientific and aeronautical objectives. The contract falls under NAICS code 541715 and is forecasted for release with a posted date of April 1, 2029. Primary point of contact for inquiries is Arlene D. Schwartz, with Robert E. Watts designated as the Small Business Specialist. Performance will be centered at Moffett Field, where the full scope of activities will be executed. Although the solicitation number and set-aside details are not specified, the contract is structured to facilitate robust support for NASA’s strategic priorities through integrated lifecycle services, with emphasis on collaboration, innovation, and mission readiness.
Ames Research Center

POSTED

in almost 3 years

DEADLINE

N/A
View Details
NAICS: 541715
New
Federal
Aeronautics and Spaceflight Systems Engineering Support Services (ASSESS) IIThe Aeronautics and Spaceflight Systems Engineering Support Services II contract is designed to advance NASA’s mission by enabling cutting-edge research and technology development across aeronautics and spaceflight systems. It focuses on supporting scientific inquiry, engineering design, analysis, and development activities that push the boundaries of current capabilities, with particular emphasis on increasing the technology readiness level of emerging systems critical to future NASA missions. The scope includes the implementation of technology programs, test operations, systems analysis, conceptual design, and comprehensive program and project management support to ensure seamless integration and execution of complex aerospace initiatives. Work under this contract will be conducted primarily at NASA’s Ames Research Center in Moffett Field, with the primary focus on sustaining and enhancing the agency’s technical infrastructure and innovation pipeline. The contract supports a broad spectrum of technical disciplines essential to the development of next-generation aircraft and spacecraft, ensuring alignment with evolving mission objectives. Point of contact for inquiries is Mary E. Livingston, with Robert E. Watts serving as the Small Business Specialist, reflecting a commitment to broad participation. The contract falls under NAICS code 541715 and is forecasted for release in 2029, positioning it as a strategic vehicle for long-term R&D collaboration with industry and academic partners.
Ames Research Center

POSTED

in almost 3 years

DEADLINE

N/A
View Details
NAICS: 541715
New
Federal
Marshall Engineering Technicians and Trades Support (METTS) IVThe METTS IV contract provides comprehensive engineering technician and trades support services to the Marshall Space Flight Center, specifically supporting the Engineering Directorate, Facilities Management Office, and various other programs and projects across the center. The contractor is responsible for delivering a broad range of technical services that span multiple disciplines and are critical to the successful execution of NASA’s mission-critical activities at Huntsville. This includes hands-on technical work, system maintenance, fabrication, testing, and other specialist trades, all performed in alignment with the detailed requirements outlined in the Performance Work Statement. The contractor must also ensure effective management and oversight to guarantee compliance with performance standards, schedule adherence, and quality control across all assigned tasks. All work is conducted at the Marshall Space Flight Center in Huntsville, and the contract is categorized under NAICS code 541715 for research and development in physical, engineering, and life sciences. Point of contact for program inquiries is Myron H. Tapscott, while Danielle R. Barnes serves as the Small Business Specialist, indicating an emphasis on small business participation. The forecasted posting date is October 1, 2027, signaling the anticipated timing for future solicitation activity.
Marshall Space Flight Center

POSTED

in over 1 year

DEADLINE

N/A
View Details
NAICS: 541715
New
Federal
Engineering and Technical Support Services for Flight Research and Development (ETSS)The contract involves providing comprehensive engineering and technical support services for flight research and development at NASA's Armstrong Flight Research Center, located in Edwards. The scope covers a wide range of specialized disciplines including research, flight operations, aerodynamics, propulsion, dynamics and controls, advanced systems development, flight instrumentation, systems integration, aerostructures research, and range and subscale flight research. Additionally, support for safety and mission assurance is a critical component of the work, ensuring the reliability and security of flight research missions. The contractor is expected to supply all necessary personnel, services, and materials to support flight research projects, internal research and development efforts, and various technical functions. This includes providing disciplinary engineering expertise across multiple research and technical domains to support NASA’s ongoing innovation and operational goals in aerospace engineering. The work is forecasted to be under the NAICS code 541715, with key agency contacts identified to facilitate communication and coordination.
Armstrong Flight Research Center

POSTED

in 6 months

DEADLINE

N/A
View Details