This Government Contract opportunity from Department Of Health And Human Services was posted on July 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Biostatistical Modeling and Causal Inference

Closed

Federal

Submission Closed07/30/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541611

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AI Contract Overview

The contract seeks to develop and validate statistical models aimed at evaluating causal relationships between the use of GLP-1 receptor agonists and changes in outcomes related to HIV and alcohol and other substance use disorders, utilizing observational data and advanced analytical techniques. The work requires robust methodological expertise in causal inference, including but not limited to propensity score matching, instrumental variables, and doubly robust estimation, to account for confounding in non-randomized data and produce reliable estimates of treatment effects. The project is grounded in real-world health datasets and must deliver validated models capable of informing public health understanding and policy decisions regarding metabolic and addiction-related comorbidities. The contract is classified as a subcontract under the NAICS code 541611 for scientific research and development services, and is sponsored by the National Institutes of Health through the National Institute on Drug Abuse under the Department of Health and Human Services. The performance location is specified as Bethesda, Maryland, with a response deadline of July 30, 2026, and the opportunity was posted on July 22, 2026. While no set-aside type is indicated, the work demands specialized biostatistical capabilities and a proven track record in analyzing complex longitudinal health data to support rigorous causal analysis in the context of emerging pharmacotherapies and their downstream impacts on critical public health domains.

General Info

Develop statistical models to assess GLP-1 agonist impacts on HIV and substance use disorders using observational data and causal inference methods.

Agency

Department Of Health And Human Services → National Institutes Of Health NidaView Agency

NAICS

541611 - Administrative Management and General Management Consulting ServicesView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

This scope was carved out of 75N95026R0007.

The full solicitation package (3 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Role of Glucagon-like Peptide-1 (GLP-1) receptor agonists versus DPP-4 inhibitors for alcohol and substance use disorders in improving HIV-related outcomes and providing health benefits in people living with HIV

AI Contract Breakdown

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Timeline

PhaseClosed

PostedJul 22

subcontract

Response DeadlineJul 30

Deadline has passed

Submission Closed

07/30/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Nida

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Nida

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Office AddressN/A

ContactsNo contact information available

Full Description

Develop and validate statistical models to assess causal relationships between GLP-1RA use and changes in HIV/ASUD outcomes using observational data and advanced analytical methods.