Multiplexed precision proteomics immunoassay panel for neurological disease biomarkers and bulk reagents

This is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with part 12. This announcement constitutes the only solicitation. Offers are being requested and a separate written solicitation will not be issued.

The solicitation number is 75N98026Q01166 and the solicitation is issued as a Request for Quotation (RFQ) for brand name or equal multiplexed precision proteomics immunoassay panel for neurological disease biomarkers and bulk reagents.

This acquisition is not set-aside for small business concerns. This solicitation incorporates provisions and clauses by reference. The full text of provisions and clauses may be accessed electronically at www.acquisition.gov.

The National Institutes of Health, Office of the Director on behalf of the National Institute of Aging (NIA) intends to negotiate and award a purchase order for brand name or equal Multiplexed precision proteomics immunoassay panel for neurological disease biomarkers and bulk reagents that are compatible with the ARGO HT System.

This acquisition is conducted as full and open for a commercial product or commercial services and is conducted pursuant to FAR 12.201-1, Simplified Procedures in accordance with 41 U.S.C. 1901.

The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2026-01 dated March 13, 2026.

NIA requires the following brand name or equal items: NULISAseq Neuro 220 Panel. Qty. 7; NULISA 10X Wash Buffer. Qty. 2. See the attached Purchase Description – Attachment 1.

Description of requirement:

Neurodegenerative disease research is complicated by a high degree of clinical heterogeneity and the prevalence of co-pathologies. The identification of clinically relevant biomarkers for neurological disorders is critical in the development of better tools for diagnosis, disease progression, and prediction of therapeutic outcomes. NIA requires a brand name or equal NULISAseq Neuro 220 Panel to provide comprehensive coverage of the hallmarks of neurodegenerative disease with highly sensitive and specific multiplexed analysis of 220 biomarkers using only 25 μL of sample, providing researchers with an automated solution to dissect disease heterogeneity, uncover co-pathologies, and identify signatures of disease prognosis, progression, and therapeutic response in clinical cohorts. See the attached Purchase Description – Attachment 1 for the required salient characteristics and details.

Delivery shall be made within 30 days after receipt of Order. Delivery shall be made to the following:
National Institute on Aging (NIA)
251 Bayview Boulevard
8C009 BRC
Baltimore, Maryland 21224
United States

The following RFO provisions are required by RFO 12.2025(a), and incorporated by reference:

• RFO 52.212-1, Instructions to Offerors-Commercial Products and Commercial Services.
• RFO 52.212-2, Evaluation – Commercial Products and Commercial Services (DEVIATION) (RFO AUG 2025), applies to this acquisition. 
  • The Government will award a contract resulting from this solicitation to the responsible Offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors will be used to evaluate offers:
    a) Technical capability of the item offered to meet the Government requirement;
    b) Price; and
    c) Past performance
    
    Technical and past performance, when combined, are significantly more important than cost or price.
    
    Notice of award. A written notice of award or acceptance of an offer furnished to the successful Offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.
    (End of provision)
     
• 52.203-18, Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements or Statements—Representation
• 52.204-7, System for Award Management—Registration
• 52.204-7, Alt. I, System for Award Management—Registration, Alternate I
• 52.204-90, Offeror Identification
• 52.207-6, Solicitation of Offers from Small Business Concerns and Small Business Teaming Arrangements or Joint Ventures (Multiple-Award Contracts)
• 52.209-12, Certification Regarding Tax Matters
• 52.219-2, Equal Low Bids
• 52.222-18, Certification Regarding Knowledge of Child Labor for Listed End Products
• 52.222-48, Exemption from Application of the Service Contract Labor Standards for Maintenance, Calibration, or Repair of Certain Equipment—Certification
• 52.222-52, Exemption from Application of the Service Contract Labor Standards for Certain Services—Certification
• 52.222-56, Certification Regarding Trafficking in Persons Compliance Plan
• 52.223-4, Recovered Material Certification
• 52.225-2, Buy American Certificate
• 52.225-4, Buy American—Free Trade Agreements—Israeli Trade Act Certificate
• 52.225-6, Trade Agreements Certificate
• 52.225-20, Prohibition on Conducting Restricted Business Operations in Sudan—Certification
• 52.225-25, Prohibition on Contracting with Entities Engaging in Certain Activities or Transactions Relating to Iran—Representation and Certifications
• 52.226-3, Disaster or Emergency Area Representation
• 52.229-11, Tax on Certain Foreign Procurements—Notice and Representation
• 52.240-90, Security Prohibitions and Exclusions Representations and Certifications

The following RFO provisions are required by RFO 12.2025(a), and incorporated by reference:

• 52.203-17, Contractor Employee Whistleblower Rights
• 52.204-13, System for Award Management—Maintenance
• 52.209-10, Prohibition on Contracting with Inverted Domestic Corporations
• 52.222-3, Convict Labor
• 52.222-50 Alt. I, Combating Trafficking in Persons
• 52.222-51, Exemption from Application of SCLS to Contracts for Maintenance, Calibration, or Repair of Certain Equipment—Requirements
• 52.222-53, Exemption from Application of SCLS to Contracts for Certain Services—Requirements
• 52.222-90, Addressing DEI Discrimination by Federal Contractors
• 52.223-11, Ozone-Depleting Substances and High Global Warming Potential Hydrofluorocarbons
• 52.223-12, Maintenance
• 52.223-20, Aerosols
• 52.223-21, Foams
• 52.226-8, Encouraging Contractor Policies to Ban Text Messaging While Driving
• 52.233-3, Protest After Award
• 52.244-6, Subcontracts for Commercial Products and Commercial Services
• The clauses at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this address: https://www.acquisition.gov/far-overhaul https://www.hhs.gov/contract-policies-regulations/hhsar-overhaul

(End of clause)

The following FAR clauses are required by FAR 12.205(b)(1) for all solicitations and incorporated by reference:

• FAR 52.212-4, Terms and Conditions—Commercial Products and Commercial Services.

The following FAR clauses are required as applicable to this requirement and incorporated by reference:

• FAR 52.217-5, Evaluation of Options (DEVIATION) (RFO SEP 2025)
• FAR 52.222-48, Exemption from Application of the Service Contract Labor Standards to Contracts for Maintenance, Calibration, or Repair of Certain Equipment-Certification (DEVIATION) (RFO Nov 2025)
• HHSAR 352.232-71 Electronic submission of payment requests

All quotes must be received by 1:00 p.m., Eastern Daylight Time, on Monday, September 14, 2026, and reference Solicitation Number 75N98026Q01166 Quotes must be submitted electronically to Lisa Anglin at lisa.anglin@nih.gov and Josh Lazarus at josh.lazarus@nih.gov.

A determination by the Government whether to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered to determine whether to proceed on a brand name or equal basis as indicated above, or to conduct a competitive procurement.

The following additional contract requirement(s) or terms and conditions as determined by the contracting officer are necessary for this acquisition and consistent with customary commercial practices. The associated NAICS code 811219 - Other Electronic and Precision Equipment Repair and Maintenance, and the small business size standard is $22M.  

FAR DEVIATION STATEMENT: “System updates may lag policy updates. The System for Award Management (SAM) may continue to require entities to complete representations based on provisions that are not included in this solicitation. Contracting officers will rely on representations from offers based on provisions in the solicitation. Entities are not required to, nor are they able to, update their entity registration to remove these representations in SAM.”

Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the services. The price quote shall include unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s), product description, and any other information or factors that may be considered in the award decision. Such factors may include special features required for effective program performance, trade-in considerations, probable life of the product selected as compared with that of a comparable product, warranty considerations, maintenance availability, and environmental and energy efficiency considerations.

Responses to this solicitation must include clear and convincing evidence of the offeror’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price proposal/quote must include the labor categories, an estimate of the number of hours required for each labor category, fully loaded fixed hourly rate or each labor category, breakdown and rationale for other direct costs or materials, and the total amount.

The Unique Entity ID (UEI) from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.