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This Combined Synopsis/Solicitation opportunity from Department Of Defense was posted on May 26, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Cap-dependent endonuclease inhibitors (CENis) - NHRC

Closed
N0018926QB059Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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AI Contract Overview

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The contract focuses on the preclinical development of cap-dependent endonuclease inhibitors (CENis), a class of small molecule antiviral therapeutics aimed at broad-spectrum activity. Activities under this project include lead candidate selection, in vitro and in vivo efficacy testing, and the characterization and optimization of these compounds. An essential component involves research support for preclinical studies of CENis against viruses necessitating biosafety level 4 (BSL-4) containment, with specific support directed to the Naval Medical Research Command located in Fort Detrick, Maryland. The overall duration of the contract is set for 36 months. Issued by the Department of Defense through the Navsup Fleet Logistics Center Norfolk, the contract is identified under solicitation number N0018926QB059 and was posted in May 2026, with a response deadline later that same month. The work is to be performed primarily in Galveston, Texas. The contract does not have any set-aside requirements and falls under the NAICS code 541715, which relates to research and development services. Key contacts for the contract are Brian Kinkade and Jacob Gephart, reachable via their provided email addresses and phone numbers.

General Info

36-month contract for developing antiviral drugs with BSL-4 research support at Fort Detrick.

Agency

Department Of Defense → Navsup Flt Logistics Ctr Norfolk

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Galveston, TX, USA

Set-Aside

NONE

Documents

(4)

PWS for Development of Broad-Spectrum CENi-Based Antivirals

PDF•pws

Solicitation+Amendment+-+N0018926QB0590001.pdf

PDF

Solicitation N0018926QB059 for Broad-Spectrum CENi-Based Antivirals Development

PDF•rfp

Solicitation N0018926QB059 Research Support Services RFQ

PDF•rfq

AI Contract Breakdown

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Timeline

PhaseClosed
Posted

Combined Synopsis

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Defense → Navsup Flt Logistics Ctr Norfolk
Contacts2 people available
OfficeNORFOLK, VA, 23511-3392, USA
Organization / Agency
Department Of Defense → Navsup Flt Logistics Ctr Norfolk
Office AddressNORFOLK, VA, 23511-3392, USA
Contacts
Brian Kinkade
contact@example.gov
+1 (555) 000-0000
Jacob Gephart
contact@example.gov
+1 (555) 000-0000

Full Description

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The preclinical development of Cap-dependent endonuclease inhibitors (CENi), a class of small molecules, as broad-spectrum antiviral therapeutics. The scope of this project includes all activities required to select lead CENi candidates, including in vitro and in vivo efficacy studies and characterization and optimization of lead compounds. This includes Research Support expertise regarding the preclinical development of cap-dependent endonuclease inhibitors (CENis) with viruses that require biosafety level 4 (BSL-4) containment to support the Naval Medical Research Command in Fort Detrick, MD. This work will be performed over a 36-month period.