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Cellular Senescence Network (SenNet): SenNet Data Coordination, Integration and Organizational Center (U24 or UM1)

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The NIH Common Fund along with the National Institute on Aging, National Cancer Institute, and additional NIH Institutes and Centers plan to release a Notice of Funding Opportunity (NOFO) for Stage 2 of the Cellular Senescence Network (SenNet) Program. This initiative aims to explore the biological effects of senescent cell heterogeneity in health and disease by identifying and characterizing tissue-specific senescence markers from human biospecimens. The ultimate goal is to support the development of senotherapeutic strategies that can improve health outcomes. A central component of this stage is the SenNet Data Coordination, Integration and Organizational Center (DCIOC), which will integrate tissue mapping efforts and data to create comprehensive Atlases of Senescence. These atlases will combine the spatial distribution of senescence biomarkers with biological and functional data covering various tissues in contexts of health, aging, and age-associated diseases. The DCIOC will also act as the organizational hub, managing consortium and outreach activities for the SenNet program. While applications are not currently being solicited, this announcement provides potential applicants with advance notice to foster collaborations and project development. The funding opportunity will use U24 or UM1 activity codes and encourages investigators with expertise in cellular senescence, innovative technology development, computational tools, and novel therapeutic targeting of senescent cells in vivo to prepare responsive applications. Contact for the program is available through the Office of Strategic Coordination at the NIH.

General Info

NIH SenNet Stage 2 funds integrating tissue-specific senescence data to develop senotherapeutic strategies.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Ajay Pillai Office of Strategic Coordination
contact@example.gov
+1 (555) 000-0000

Full Description

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The NIH Common Fund, National Institute on Aging, National Cancer Institute and additional NIH Institutes and Centers (ICs) intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for Stage 2 of the Cellular Senescence Network (SenNet) Program, which seeks to understand the biological consequences of senescent cell heterogeneity in health and disease, identify and characterize tissue-specific senescence markers in human biospecimens to facilitate the development of senotherapeutic strategies that improve health outcomes. The program’s SenNet Data Coordination, Integration and Organizational Center (DCIOC) will integrate tissue mapping efforts with Stage 2 data to generate Atlases of Senescence incorporating the spatial distribution of senescence biomarkers with biological and functional data across tissues in health, lifespan and age-associated diseases. The DCIOC will also serve as the organizational hub for SenNet in managing consortium and outreach activities. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 or UM1 activity code. Investigators with expertise and insights into the cellular senescence impact on human health, the development of innovative technologies and computational tools to identify and characterize senescent cells and inform novel approaches for the strategic targeting of senescent cells in vivo are encouraged to apply in response to these new NOFOs.

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