This Subcontract opportunity from Department Of Defense was posted on September 24, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Clinical Research Organization (CRO) / Clinical Trial Management

Closed

Federal

Submission Closed10/23/2026, 12:00:00 PM EDT

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

Grant

Request for Information (RFI): Seeking New and Emerging Areas of Science Relevant to the NIDCD Mission, To Inform an Update of the NIDCD Strategic Plan for 2028-2032

Solicitation # NOT-DC-26-008

The National Institute on Deafness and Other Communication Disorders is issuing a Request for Information to gather input on new and emerging scientific areas to inform the development of its 2028-2032 Strategic Plan. In accordance with the 21st Century Cures Act, the agency is seeking suggestions from the general public, academic researchers, clinical practitioners, and advocacy groups regarding advancements in hearing, balance, taste, smell, voice, speech, and language that are not currently addressed in the 2023-2027 plan. Interested parties must submit their electronic responses by December 11, 2026. This process is voluntary and intended solely for planning purposes; it is not a solicitation for grant applications or proposals, and no awards will be made based on the submissions. Respondents are cautioned not to include proprietary or personally identifiable information, as the government cannot guarantee confidentiality and may use the submitted data in future reports or funding opportunity announcements.

National Institute On Deafness And Other Communication Disorders

POSTED

DEADLINE

Request for Information: Developing Menopause Common Data Elements

Solicitation # NOT-OD-26-111

The National Institutes of Health (NIH) has issued a Request for Information to gather input for the development of Common Data Elements (CDEs) focused on menopause. The goal is to create a standardized set of questions and response options to improve the consistency, interoperability, and reproducibility of data collected across research, clinical care, and public health settings. By harmonizing how menopause-related data is recorded, the NIH aims to better understand women's midlife health and the long-term impacts of various treatments. The NIH is seeking feedback on priority domains, including menstrual history, menopausal status, symptoms, biomarkers, and patient-reported outcomes. The proposed framework suggests a tiered approach consisting of core elements for universal collection, supplemental elements for specific thematic aims, and exploratory elements for emerging technologies and biomarkers. Additionally, the initiative seeks guidance on aligning these elements with existing health standards, ensuring representation across diverse populations, and minimizing the burden on participants and providers during implementation.

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Guidance, Navigation, and Control (GNC) AlgorithmsThis subcontract focuses on the design and development of control systems and software algorithms for prime contractors supporting DARPA Anzio spacecraft projects. The scope of work includes the creation of flight control laws, autonomous guidance systems, and trajectory optimization algorithms, all developed using high-fidelity flight simulation software. The primary deliverables for this effort are control system software and detailed simulation performance reports. Managed under the Department of Defense for the Defense Advanced Research Projects Agency, the project falls under NAICS code 541715. Due to the sensitive nature of the work, contractors must maintain strict cybersecurity standards, specifically requiring compliance with NIST SP 800-171 and CMMC Level 2. The solicitation was posted on November 9, 2026, with a response deadline of December 1, 2026.

Defense Advanced Research Projects Agcy

POSTED

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HERMES BAA CALL: Rotating Detonation Rocket Engine-Combined Cycle (RDRE-CC) Flight Demonstration

Solicitation # FA9300-20-S-0001-CALL-RDRE-CC

The Air Force Research Laboratory Rocket Propulsion Division is seeking innovative research and development to advance Rotating Detonation Rocket Engine-Combined Cycle propulsion systems from TRL 3 to TRL 6. This effort aims to culminate in a ground-launched flight demonstration to support High-Speed Affordable Mass Munitions. The acquisition follows a two-step process, beginning with the submission of a technical white paper and rough order of magnitude cost, with selected offerors later invited to submit full technical and cost proposals. The anticipated period of performance is 36 to 48 months. Key submission requirements include a ten-page core white paper and an optional five-page technical appendix. While narrative text must be double-spaced, single-spacing is permitted within tables and graphics. Due to the presence of Controlled Unclassified Information, submissions must be sent via DoD SAFE drop requests to Contracting Officers Mathew Pierson and Kameelah Purdom, as the generic workflow inbox is no longer in use. Additionally, the government will utilize a non-government advisor from Sierra Lobo, Inc. for technical evaluation, and vetted contractors must use their CAGE code to access controlled technical Q&A documents via SAM.gov.

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Venous Thrombosis (VT)

Solicitation # 80JSC026Q0014

Solicitation 80JSC026Q0014 is a combined synopsis and request for quotations issued by the NASA Johnson Space Center for a firm-fixed-price contract. The project seeks applied research and the development of current or novel approaches to surveil, reduce risk of, and prevent or treat venous thrombosis during spaceflight and exploration missions. The scope of work encompasses preflight medical screening, individual risk assessments, monitoring approaches, and both prophylactic and treatment countermeasures. Specifically excluded from this requirement are pharmaceutical treatments, AI/ML modeling, Earth-independent decision-making tools, and tissue chip or organoid pathophysiology development. The contract features a base period of performance from January 7, 2027, to September 30, 2031, with four optional years. This is a full and open competition for commercial products under NAICS code 541715. Award decisions will be based on a two-step evaluation process consisting of a compliance check followed by a trade-off analysis. Technical acceptability and past performance are weighted as significantly more important than price. Proposals must adhere to Dual-Anonymous Peer Review guidelines, separating attributable information from the technical quote. All responses must be submitted electronically by 1:00 PM CST on November 20, 2026, with technical and contractual questions due by October 30, 2026.

NASA Johnson Space Center

POSTED

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Solicitation # DARPA-SN-27-06

The Anzio program, managed by the Defense Advanced Research Projects Agency Tactical Technology Office, focuses on developing innovative aero-assist technologies for spacecraft to enable large, rapid, and precise orbit transfers while reducing propellant requirements. Key areas of interest include thermal protection systems, control systems and algorithms, atmospheric sensing, and lightweight aeroshells. The program specifically excludes technology areas such as communications, power management, spacecraft buses, payloads, propulsion systems, and existing orbital transfer vehicles. This specific notice, DARPA-SN-27-06, is a Special Notice for an Industry Day event scheduled for December 16-17, 2026, in Arlington, Virginia. It is not a formal solicitation for proposals or abstracts. Interested parties must register and submit PDF posters for approval by December 1, 2026. To handle Controlled Unclassified Information, participants must comply with NIST Special Publication 800-171 and maintain a CMMC Level 2 Self Assessment. All inquiries regarding the notice should be directed to [email hidden].

Defense Advanced Research Projects Agcy

POSTED

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Airlift Efficiency Commercial Solutions Opening (CSO) - Amendment 01

Solicitation # FA4452-25-S-C001

The Airlift Efficiency Commercial Solutions Opening (CSO), solicitation FA4452-25-S-C001, is a competitive, unrestricted effort hosted by the 763rd Enterprise Sourcing Squadron for the Air Force Operational Energy Office. The program seeks innovative commercial technologies and services to improve airlift efficiencies for military and commercial transport aircraft. The solicitation follows a two-step process consisting of an initial Solution Brief and a subsequent Detailed Approach for invited participants. Awards will be made as Firm-Fixed Price contracts or Other Transaction Agreements, with evaluations weighted equally across technical merit, importance to the agency, and price. The first Area of Interest (AOI) focuses on a dual-use propulsion system engine with 35,000 to 50,000 lbs of thrust, intended for the C-17 Globemaster and Blended Wing Body (BWB) platforms. Key requirements include compliance with current and future emissions standards, entry into service by 2030, and a scalable production plan capable of delivering up to 80 engines per month by 2037. The government strongly encourages cost-share arrangements or unconventional project financing to mitigate development risks. Solution briefs for this AOI are due by March 13, 2025, and must be submitted as unclassified documents.

POSTED

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Polar Rover for Observation, Mapping, and In-Situ Exploration (PROMISE) Mission

Solicitation # 2027_PROMISE

NASA Marshall Space Flight Center

POSTED

DEADLINE

Helmet-Mounted First-Person View Display System

Solicitation # SOFATL-KP_27-06

POSTED

DEADLINE

ACC-DTA Commercial Solutions Opening (CSO)

Solicitation # W912CH-26-S-0001

The Army Contracting Command – Detroit Arsenal (ACC-DTA) Commercial Solutions Opening (CSO), solicitation W912CH-26-S-0001, is a rapid-acquisition gateway designed to transition cutting-edge commercial technologies into active defense programs. This vehicle supports a diverse customer base, including the Intelligence and Security Command (INSCOM) and six Portfolio Acquisition Executives, focusing on the development, integration, and sustainment of ground vehicle systems to enhance Army modernization and readiness. The CSO utilizes a streamlined, merit-based, multi-phased evaluation process consisting of solution briefs, presentations, and commercial solution proposals. Awards may be issued through 2028 as FAR Part 12 commercial contracts, non-FAR transaction agreements under 10 U.S.C. 4022, or Cooperative Agreements under 31 U.S.C. 6305. The solicitation encompasses various Areas of Interest (AoIs) with diverse technical requirements and funding profiles. Notable efforts include the FALCONS prototype program for long-range reconnaissance sensors, with funding ceilings of $24 million to $30 million depending on the use of government-provided hardware, and the TIGER Readiness initiative focused on supply chain resilience and advanced manufacturing for the Abrams Main Battle Tank's AGT 1500 engine. Other active or previous AoIs include counter-UAS detection, mobile camouflage systems, domestically produced hand tools, and small unit water purification. Offerors must be registered in the System for Award Management (SAM) and, for specific programs, demonstrate strict compliance with the Buy American Act and Specialty Metals clauses, ensuring no reliance on adversarial foreign nations for critical minerals.

POSTED

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Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Solicitation # ARPA-H-SOL-26-163

The Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) program, issued by the Advanced Research Projects Agency for Health (ARPA-H) Proactive Health Office under solicitation ARPA-H-SOL-26-163, seeks innovative solutions to identify and act upon autism trajectories across the lifespan. The program focuses on the nonlinear interactions of genetic, biological, behavioral, and environmental factors to move toward personalized care. The scope is divided into four Technical Areas: TA1 focuses on multi-factor analysis and trajectory identification; TA2 involves population-scale modeling and data integration; TA3 centers on precision intervention and trajectory testing; and TA4 targets technologies for communication, quality of life, and embedded assessment. Awards will be made using Other Transaction (OT) instruments through a two-stage submission process consisting of a Solution Summary and a Full Proposal. Technical performance is monitored via a milestone-based system with evaluation gates at Month 10, Month 22, and a final evaluation at Month 46. Key requirements include strict adherence to HIPAA Privacy Rule de-identification standards, the implementation of independent data safety monitoring boards for harm surveillance, and the disclosure of any organizational conflicts of interest. Submissions must follow specific formatting guidelines, including the use of Avenir Next LT Pro font for summaries and a multi-volume structure for full proposals, with a response deadline of December 2, 2026.

Advanced Research Projects Agency For Health (arpa-H)

POSTED

DEADLINE

Exploratory Advanced Research (EAR) Program FY 2027 Data Science Solicitation

Solicitation # 693JJ3-27-BAA-0002

The Exploratory Advanced Research (EAR) Program FY 2027 Data Science Solicitation, identified as 693JJ3-27-BAA-0002, is a Broad Agency Announcement issued by the Federal Highway Administration (FHWA) within the Department of Transportation. The program seeks to identify and fund high-risk, high-payoff research focused on applying emerging and advanced data analytic techniques to improve the safety, durability, efficiency, and environmental impact of highway and intermodal transportation systems. Key objectives include expanding the community of researchers in data science for transportation and increasing the availability of well-documented highway transportation data. The expected period of performance for awarded projects is 60 months, with most instruments anticipated to be firm-fixed-price contracts, although cost-reimbursement arrangements may be permitted for awardees with approved accounting systems. The government will utilize a best-value determination based on an integrated evaluation of technical capability, past performance, and cost/price. Technical capability is the most important non-price factor, and combined non-price factors are approximately equal in weight to cost/price. The selection process involves a two-phase approach, beginning with a project concept paper rated as acceptable or not acceptable, followed by a formal project proposal. While there are no exclusive set-asides, the solicitation strongly encourages submissions from small businesses, including disadvantaged, veteran-owned, and woman-owned concerns, as well as Historically Black Colleges and Universities and Minority Institutions. Proposals must be submitted in electronic PDF format and organized into three volumes: a technical proposal with a 20-page limit, cost and pricing data, and supplemental information regarding intellectual property. Key requirements include registration in the System for Award Management (SAM), the provision of a Unique Entity Identifier (UEI), and the submission of a Small Business Subcontracting Plan for non-small business entities with awards exceeding 900,000 dollars. Additionally, the FHWA will maintain unlimited rights to any software and source code delivered under the contract. The response deadline for this solicitation is December 21, 2026.

693JJ3 Acquisition And Grants Mgt

POSTED

about 16 hours ago

DEADLINE

in about 1 month

AI Contract Overview

This subcontract focuses on providing Clinical Research Organization services to support USAMRDC medical product projects for the Defense Health Agency. The selected provider will be responsible for the design, execution, and management of clinical trials, specifically focusing on antimicrobial medical devices and wound care. Key operational duties include managing IRB and IACUC approvals, developing product claim matrices, and ensuring all data-quality objectives are met. The contractor is expected to deliver comprehensive clinical study reports and data-quality verification reports. This effort falls under NAICS code 541715 and requires the ability to support prime contractors in delivering a validated matrix of supported product claims. The response deadline for this opportunity is October 23, 2026.

General Info

CRO services for USAMRDC medical product projects focusing on antimicrobial devices and wound care.

Agency

Department Of Defense → Defense Health Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

28360, MD, USA

Set-Aside

NONE

Documents

This scope was carved out of HT9427-26-R-E020.

The full solicitation package (15 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Prototype development for Battlefield Wound Infection Prevention and Treatment (BWI P&T) Barrier Combination

AI Contract Breakdown

Uniform Contract Format

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Timeline

PhaseClosed

PostedSep 24

subcontract

Response DeadlineOct 23

Deadline has passed

Submission Closed

10/23/2026, 12:00:00 PM EDT

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Organization & Contact Information

AgencyDepartment Of Defense → Defense Health Agency

ContactsNo contacts available

OfficeN/A

Organization / AgencyDepartment Of Defense → Defense Health Agency

Office AddressN/A

ContactsNo contact information available

Full Description

Performs and manages clinical trials for prime contractors on USAMRDC medical product projects. Designs and executes clinical studies, develops product claim matrices, and ensures data-quality objectives. Manages IRB and IACUC approvals for wound care or antimicrobial medical devices. Delivers clinical study reports, data-quality verification reports, and a matrix of supported product claims.