customized configured cryoEM Mainstream GPU Workstation/System

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NICHD-22-271 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2022-06. The North American Industry Classification (NAICS) Code is 541511 and the business size standard is $30m. However, this solicitation is not set aside for small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intends to contract on a sole source basis with Single Particle, LLC of San Diego, CA to procure a customized configured cryoEM Mainstream GPU Workstation/System, etc. 1. Single Particle, LLC cryoEM Mainstream 4U rack-mountable GPU Workstation, 3-Year Parts & Labor Warranty, SP Quality Burn-in Testing SPcare Plan (1st year) included OS and Cryo-EM software Pre-installation OS and Cryo-EM Software Remote Maintenance - QTY (1) EA 2. Performance add-on: upgrade to 2x Intel Xeon Silver 4316 Processor 20-Core - QTY (1) EA 3. Performance add-on: upgrade to 4x NVIDIA RTX 3090 Graphics Cards,24GB GDDR6x - QTY (1) EA 4. Pre-install OS and Cryo-EM software package to include/not limited to Cent OS 7 RELION4.0.beta RELION3.1.3 RELION2.1.0, etc. and installation - QTY (1) EA 5. Pre-install Cryo-EM software set - Ubuntu - QTY (1) EA 6. SPcare Plan (1-year remote help desk service) Within the valid period, SPcare Help Desk Support plan covers an unlimited number of support incidents for hardware and software diagnosis and troubleshooting. - QTY (2) EA Data processing in cryoEM is computationally a very intensive process and often one has to process multiple datasets to ascertain which one to proceed with for final model building. This gets repeated for every protein or protein complex. The lab is currently pursuing several targets in our lab and thus require a computational workstation for our lab. Single Particle LLC was started by scientists with specific expertise in the area of cryoEM to configure, build and provide computational workstations for cryoEM. This customized workstation is configured by Single Particle, LCC specifically for the NIH Lab and cannot be procured from another vendor/source. Single Particle LLC is the exclusive supplier of SingleParticle Mainstream/Performance cryoEM Workstation and cryoEM Storage Server in North America. This customized workstation will provide exactly the set-up that the labs need to accomplish the data processing in cryoEm work. This setup is a turnkey/ready to run workstation that can be easily setup and ready to use quickly. Unique Specifications and Features, etc.: 1. Cryo-electron microscopy (cryoEM) software packages pre-installation: RELION4 EMAN2+SPARX (SPHIRE) Gctf + Gautomatch MotionCorr + MotionCor2 Frealign + CTFFIND4 + Unblur 2. SPcare Service Plan a) Unlimited supports for hardware and software application diagnosis and troubleshooting b) OS and Cryo-EM software stack pre-installation c) Promptly OS and Cryo-EM software update and re-installation on demand d) RELION optimization and automation provided 3. Dr. SP Service Limited consultation for end users. Enable scientists to use common image processing packages including but not limited to RELION and AlphaFold to attain high-resolution 3D structures The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under authority of the 41 U.S.C. 253(c) (1), FAR 6.302. This notice of intent is not a request for competitive quotations. The offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors - Commercial Items; FAR Clause 52.212-2, Evaluation - Commercial Items-; FAR Clause 52.212-4, Contract Terms and Conditions - Commercial Items; and FAR 52.212-5 (August 2020), Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items - Deviation for Simplified Acquisitions applies to this acquisition. The offeror must include their Unique Entity ID (UEI) the Taxpayer Identification Number (TIN), and the certification of business size. The contractor/offeror must provide a completed copy of FAR 52.204-24, "Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment" with their quote in response to this solicitation. The contractor/offeror must provide a completed copy of attached FAR 52.225.2, Buy American Certificate. The clauses are available in full text at https://www.acquisition.gov/Far/. Interested vendors capable of furnishing the government with the products/items and services specified in this synopsis should submit a copy of their quotation/offer to the following email address: contact@example.gov by the due date and time below. Attn: Tina Robinson. Offers must also be accompanied by descriptive literature, warranties and/or other information that demonstrates that the offer meets all the foregoing requirements. Offeror must include the delivery date/timeframe with offer. Note: Delivery address Fisher Lane location in Rockville, MD 20852. Quotations will be due on August 31, 2022, before 5:00 pm EST. The quotation must reference - Solicitation number NICHD-22-271 and - Solicitation number NICHD-22-271 must be on/in subject line of email. All responsible sources may submit a quotation, which if timely received, shall be considered by the agency. Any questions must be sent via email to contact@example.gov and must include Solicitation# NICHD-22-271 in the subject line of email. Note: In order to receive an award, contractor must be registered as all awards and have valid certification in the System for Award Management (SAM) @ www.Sam.gov. Lack of valid registration in SAM will make an offeror ineligible for award.