Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA)
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The National Institute on Aging (NIA) within the Department of Health and Human Services plans to issue a Notice of Funding Opportunity for the establishment of a Data Coordinating Center. This center will create the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA), a unified research resource designed to integrate and disseminate multiscale mouse brain datasets, specifically multi-omic and connectomic data emerging from the AD Multimodal Atlas Projects (AD-MAPs). The selected center will utilize the AD Knowledge Portal infrastructure to host and disseminate multimodal datasets, facilitate collaborative analyses among contributing teams, and develop tools for multiscale data integration. Additionally, the project requires the creation of a web-based interface for data visualization. This opportunity will utilize the U24 activity code and is currently in the forecast stage to allow potential applicants time to develop collaborations.
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Full Description
The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to invite applications proposing a Data Coordinating Center that integrates and disseminates multiscale mouse brain datasets for the aging and Alzheimer’s disease (AD) research community. The Data Coordinating Center will establish the Aging and AD Mouse Brain Atlas (AD-MBA), which will serve as a central, unified research resource for multi-omic and connectomic mouse brain datasets emerging from the NIA AD Multimodal Atlas Projects (AD-MAPs). The Data Coordinating Center will (1) leverage the NIA-supported AD Knowledge Portal data infrastructure to facilitate hosting, deposition, and dissemination of multimodal datasets generated by the AD-MAPs program, (2) facilitate collaborative analyses among the data-contributing teams, (3) develop/optimize and incorporate tools for multiscale integration of multi-omics and connectomics datasets, and (4) create a broadly accessible web-based interface for the visualization and dissemination of integrated multiscale data. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U24 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
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