Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA)
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AI Contract Overview
The National Institute on Aging (NIA) plans to release a Notice of Funding Opportunity (NOFO) seeking applications for a Data Coordinating Center that will manage and disseminate integrated multiscale mouse brain datasets related to aging and Alzheimer’s disease. This center, known as the Aging and AD Mouse Brain Atlas (AD-MBA), will serve as a centralized resource to unify multi-omic and connectomic datasets generated from the AD Multimodal Atlas Projects (AD-MAPs). It will leverage existing NIA-supported infrastructure to support hosting, depositing, and sharing these datasets, while also fostering collaboration among contributing research teams. The Data Coordinating Center will be responsible for developing and optimizing tools that integrate diverse datasets at multiple scales and creating a user-friendly web interface for broad public access to the data. Although formal applications are not currently being accepted, this announcement gives researchers advance notice to form collaborations and design responsive proposals using the U24 cooperative agreement mechanism. Investigators with expertise in aging and Alzheimer’s disease research are encouraged to prepare for this upcoming funding opportunity, which aims to enhance the availability and utility of comprehensive mouse brain data for the research community.
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The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to invite applications proposing a Data Coordinating Center that integrates and disseminates multiscale mouse brain datasets for the aging and Alzheimer’s disease (AD) research community. The Data Coordinating Center will establish the Aging and AD Mouse Brain Atlas (AD-MBA), which will serve as a central, unified research resource for multi-omic and connectomic mouse brain datasets emerging from the NIA AD Multimodal Atlas Projects (AD-MAPs). The Data Coordinating Center will (1) leverage the NIA-supported AD Knowledge Portal data infrastructure to facilitate hosting, deposition, and dissemination of multimodal datasets generated by the AD-MAPs program, (2) facilitate collaborative analyses among the data-contributing teams, (3) develop/optimize and incorporate tools for multiscale integration of multi-omics and connectomics datasets, and (4) create a broadly accessible web-based interface for the visualization and dissemination of integrated multiscale data. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U24 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
