This Government Contract opportunity from Department Of Defense was posted on June 2, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

Directed Energy & Low-Cost Interceptor R&D

Closed

Federal

Submission Closed05/08/2026, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

Federal

Machine Learning & Predictive Analytics EngineeringThis subcontract, titled Machine Learning and Predictive Analytics Engineering, is issued by the Naval Air Systems Command under the Department of Defense. The project focuses on the development and deployment of production-ready machine learning algorithms to support prime contractors on F-35 Joint Program Office projects. Key objectives include creating solutions for supply-chain optimization, readiness forecasting, and predictive maintenance, utilizing ML engineering pipelines within AWS and Azure GovCloud architectures. The scope of work involves managing CI/CD/CT pipelines and delivering validated source code and predictive models. Due to the nature of the work, an active Top Secret clearance is required. The performance location for this contract is Arlington, Virginia, with a response deadline set for November 10, 2026.

Naval Air Systems Command

POSTED

DEADLINE

Senior Advisor SME – Patient Advocacy for Ultra-Rare Neurological DiseasesThis small business set-aside subcontract, managed through the Department of Health and Human Services Omas Strategic Buying Center, seeks a Senior Advisor Subject Matter Expert in Patient Advocacy for Ultra-Rare Neurological Diseases. The role involves providing executive-level strategic advisory services for prime contractors working on NIH NINDS projects, specifically focusing on technical feedback for biologic drug discovery and gene-based therapy trials related to nervous system conditions. The selected expert will serve on the URGenT External Counselor Board to evaluate project milestones and resolve complex drug development challenges. Based in Rockville, the position requires a high level of expertise in both drug discovery and patient advocacy to deliver critical strategic recommendations and technical evaluations.

Omas Strategic Buying Center - Professional Services

POSTED

DEADLINE

Digital Biomarker & Computational Modeling DevelopmentThis subcontract focuses on the development and validation of objective digital biomarkers and computational models to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves utilizing high-performance computing and AI/ML software frameworks to create algorithms for early disease detection and predictive models for disease forecasting. The project requires strict adherence to HIPAA compliance and FDA software validation standards to ensure the integrity and security of the delivered models. Performance will take place in Frederick, Maryland, with the primary objective of delivering validated digital biomarkers and predictive tools to the Department of Defense.

Defense Health Agency

POSTED

DEADLINE

TBI & Psychological Health Research Services

Defense Health Agency

POSTED

DEADLINE

Pharmacology and Pain Subject Matter Expert (SME)This subcontract opportunity is for a Pharmacology and Pain Subject Matter Expert to provide executive-level strategic guidance and technical expertise for prime contractors supporting NIH NINDS HEAL Initiative projects. The selected expert will serve as a member of the External Oversight Committee, focusing on the acceleration of non-addictive analgesic drug targets. Key responsibilities include participating in monthly teleconferences, attending ad-hoc milestone calls, delivering technical reports, and completing one annual on-site visit to the NIH campus in Bethesda, Maryland. Managed through the Department of Health and Human Services Omas Strategic Buying Center, this requirement is designated as a Total Small Business Set Aside under NAICS code 541715. The solicitation was posted on October 27, 2026, with a response deadline of November 3, 2026.

Omas Strategic Buying Center - Professional Services

POSTED

DEADLINE

Senior Advisor for Pharmacology and Pain (HEAL Initiative)This subcontract opportunity is for a Senior Advisor for Pharmacology and Pain to support the NIH HEAL Initiative through the Omas Strategic Buying Center within the Department of Health and Human Services. The selected expert will provide executive-level strategic guidance and technical feedback to prime contractors, specifically focusing on the discovery and development of non-addictive analgesic therapeutics. Key responsibilities include serving as a Subject Matter Expert on the External Oversight Committee, attending monthly meetings and ad-hoc milestone calls, and delivering detailed technical reports. Qualified candidates must possess recognized expertise in Pharmacology and Pain to effectively guide project milestones. The solicitation was posted on October 27, 2026, with a response deadline of November 3, 2026. This professional services engagement falls under NAICS code 541715 and is designed to ensure high-level technical oversight for critical drug development initiatives.

Omas Strategic Buying Center - Professional Services

POSTED

DEADLINE

Novel Materials Analysis SupportThe Novel Materials Analysis Support subcontract involves providing specialized research and analysis to characterize, detect, and quantify materials of interest for prime contractors supporting Air Force Technical Applications Center projects. The scope of work includes investigating research and development technologies to improve detection methods and utilizing chemical analysis tools and specialized hardware to quantify novel materials. The successful provider will be responsible for delivering detailed analysis reports and quantification data. This effort is managed under the Department of Defense for the agency FA7022 Amic Det 2 Ol Patrick Pka, with performance taking place at Patrick Air Force Base. Due to the sensitive nature of the work, a TS/SCI security clearance is required. The opportunity is categorized under NAICS code 541715, with a response deadline set for November 14, 2026.

FA7022 Amic Det 2 Ol Patrick Pka

POSTED

DEADLINE

Analytical Laboratory R&D (Methods & Technology)The Analytical Laboratory R&D (Methods & Technology) subcontract focuses on the development and testing of new analytical methods and technologies to improve the forensic analysis of field samples for Air Force Technical Applications Center projects. The scope of work involves performing research, development, test, and evaluation to concentrate target compounds from complex matrices, conducting extensive literature searches, and evaluating new analytical instrumentation. These tasks require the use of advanced laboratory tools and forensic instrumentation to deliver finalized analytical protocols and equipment evaluations. This Department of Defense project is managed by the Amic Det 2 Ol Patrick Pka and is performed at Patrick Air Force Base. Due to the nature of the forensic and technical work, a TS/SCI security clearance may be required for personnel. The opportunity is categorized under NAICS code 541715, with a response deadline set for November 14, 2026.

FA7022 Amic Det 2 Ol Patrick Pka

POSTED

DEADLINE

Chemical Process Modeling & Simulation (ChemCAD)This subcontract for the Department of Defense involves the research, development, and maintenance of chemical process models to support prime contractors on Air Force Technical Applications Center projects. The scope of work focuses on developing and updating ChemCAD models, enhancing software for thermodynamics and emission methodology, and conducting RDT&E to determine chemical manufacture constraints. Successful execution requires the use of ChemCAD software and specialized thermodynamic databases, with final deliverables consisting of technical reports and updated software models. The project is managed by the Department of Defense under agency FA7022 Amic Det 2 Ol Patrick Pka and will be performed at Patrick Air Force Base. Due to the sensitive nature of the work, a Top Secret security clearance is mandatory for personnel. Interested parties should note the response deadline of November 14, 2026, and the classification under NAICS code 541715.

FA7022 Amic Det 2 Ol Patrick Pka

POSTED

DEADLINE

Ammonia-Assisted Regeneration for Longer-Lasting Direct Air Capture (DAC)

Solicitation # S-167699

Triad - DOE Contractor

POSTED

DEADLINE

Space Power and Reactor Capabilities (SPARC) - Sources Sought Notice

Solicitation # 80GRC026R0009_PS

NASA Glenn Research Center

POSTED

DEADLINE

Atomically Precise Molecules (APM)

Solicitation # DARPA-PS-26-141

The Atomically Precise Molecules (APM) program, solicitation DARPA-PS-26-141, is a 36-month initiative by the DARPA Multi X Office seeking innovative synthesis techniques for programmable precision polymers (PPPs) and nonlinear optical (NLO) materials. The program aims to develop scalable materials with strictly controlled monomer sequences and compositions, culminating in a prototype NLO material integrated into a government-provided electro-optic modulator capable of achieving greater than 1THz modulation. The effort is structured in two phases, with Phase I lasting 12 months and focusing on synthesis capabilities. Research limited to inorganic materials or incremental improvements to existing state-of-the-art practices is specifically excluded. Awards will be issued as Other Transaction for Prototype Agreements, with payments processed through the Wide Area Workflow system based on a schedule of milestones. Proposals are due by December 18, 2026, via the Broad Agency Announcement Tool and must include technical, management, and pricing volumes. Eligibility is restricted to U.S. organizations, and all performers must comply with CMMC Level 2 self-certification and NIST SP 800-171 standards for safeguarding Controlled Unclassified Information. Evaluation will be based on technical approach, relevance to the DARPA mission, budget realism, and the capability to transition the technology to military or commercial sectors.

Defense Advanced Research Projects Agcy

POSTED

1 day ago

DEADLINE

in about 2 months

AI Contract Overview

The contract focuses on the research and development of advanced defensive fire solutions aimed at countering missile threats through the integration of directed energy systems, such as high-power lasers, and low-cost kinetic interceptors. The goal is to create scalable, cost-effective, and responsive defensive capabilities that enhance missile defense by combining precision energy-based interception with affordable, high-volume kinetic countermeasures. This effort targets the acceleration of technological maturity and fielding readiness for next-generation defense systems under the Department of Defense’s purview, with performance centered at Redstone Arsenal, Alabama. The solicitation is structured as a subcontract under NAICS code 541715, indicating it falls under research and development in the physical, engineering, and life sciences sector. It was posted on June 2, 2026, with a response deadline of May 8, 2026, at 9:00 PM, suggesting the timeline may reflect a future posting or administrative error. The contracting activity is managed by W6QK Acc-Rsa, aligning with DoD innovation initiatives to modernize homeland and forward-deployed defense architectures. No set-aside designation is specified, implying open competition among qualified contractors capable of advancing directed energy and kinetic interceptor technologies to operational readiness.