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DoW Duchenne Muscular Dystrophy Clinical/Translational Award

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HT942526DMDRPCTRAGrant

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The FY26 Duchenne Muscular Dystrophy Research Program (DMDRP) Clinical/Translational Research Award (CTRA), solicitation number HT942526DMDRPCTRA, is issued by the Defense Health Agency to support advanced translational research aimed at accelerating clinical applications for Duchenne muscular dystrophy. The program emphasizes therapies efficacious across the entire life span and allows for pilot clinical trials and clinical trial readiness studies. All applications require preliminary data and must address at least one of the FY26 CTRA Focus Areas. Approximately 8.46 million dollars is expected to fund about six awards, with a two-tier review process consisting of a peer review for technical merit followed by a programmatic review for relevance to military health and program priorities. Funding is available at two levels: Level 1 for smaller, less complex research with a performance period of up to three years, and Level 2 for larger, more complex research with a period of up to four years. Cost caps range from 910,000 dollars for a Single PI at Level 1 up to 1.9 million dollars for a Partnering PI Option (PPIO) at Level 2. The PPIO specifically supports collaborations involving early-career investigators or established interdisciplinary experts transitioning into the DMD field. Applicants must maintain active registrations in SAM.gov, eBRAP.org, and Grants.gov, and must disclose all foreign affiliations of key personnel to avoid the withdrawal of funding recommendations. The application process requires a pre-application by September 4, 2026, and a full application by September 18, 2026. Required documentation includes a project narrative, statement of work with data-sharing milestones, and various abstracts and impact statements. Awardees are subject to DoDGARs and must provide annual and final technical progress reports via the Research Performance Progress Report (RPPR). Clinical trials must be registered on ClinicalTrials.gov and post informed consent forms on a public federal website. Final selection is based on technical merit, programmatic relevance, and pass/fail gates regarding integrity, business ethics, and foreign affiliation disclosures.

General Info

DHA funding for DMD translational research, offering six awards totaling 8.46 million dollars.

Agency

Department Of Defense → Department Of The Army -- UsamraaView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(1)

FY26 Duchenne Muscular Dystrophy Research Program Clinical/Translational Research Award Funding Opportunity HT942526DMDRPCTRA

PDFfunding-opportunity

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Organization & Contact Information

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AgencyDepartment Of Defense → Department Of The Army -- Usamraa
Contacts1 person available
OfficeUSA
Organization / Agency
Department Of Defense → Department Of The Army -- Usamraa
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Office AddressUSA
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Full Description

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Summary: The fiscal year 2026 (FY26) Duchenne Muscular Dystrophy Research Program (DMDRP) Clinical/Translational Research Award (CTRA) supports advanced translational research to accelerate promising ideas in Duchenne muscular dystrophy (DMD) research toward clinical applications. Research must address at least one of the FY26 CTRA Focus Areas. Research projects investigating therapies that will be efficacious across the life span are strongly encouraged.


Distinctive Features: The FY26 CTRA offers two funding levels:


Funding Level 1 to support smaller, less complex preclinical and/or clinical research.


Funding Level 2 to support larger, more complex preclinical and/or clinical research.


The FY26 CTRA also offers a Partnering PI Option (PPIO) to support meaningful and productive partnerships between two investigators collaborating on the proposed research project. The PPIO has two eligibility categories:


Early-Career Partnering PI category for an independent, early-career investigator within 10 years of their first faculty appointment (or equivalent) by the time of application submission.


Established Interdisciplinary Partnering PI for independent investigators at all academic levels, or equivalent, in an area other than muscular dystrophy, seeking to transition to a career in DMD, thereby bringing their expertise to the field.


Preliminary data are required for all applications. Pilot clinical trials and clinical trial readiness studies to better inform development of drugs, devices, and other interventions are allowed.

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