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This Solicitation opportunity from Department Of Health And Human Services was posted on October 5, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Restorative and health-Enhancing Sleep Time (REST)

Closed
ARPA-H-SOL-26-159Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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POSTED

1 day ago

DEADLINE

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AI Contract Overview

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The Restorative and health-Enhancing Sleep Time (REST) program, solicitation ARPA-H-SOL-26-159, is an initiative by the Advanced Research Projects Agency for Health (ARPA-H) Proactive Health Office to transform the measurement and treatment of poor sleep, specifically insomnia. The program seeks to develop objective, home-based, closed-loop technologies capable of detecting health-relevant sleep microstructures and responding to them in real time. The scope is divided into two technical areas: Technical Area 1 (Measure & Diagnose), focusing on validated in-home systems for objective physiological measurement and mechanistic classification, and Technical Area 2 (Control & Treat), focusing on noninvasive closed-loop systems that adapt interventions to a user's physiology. The ultimate clinical goals are to increase insomnia treatment response from 50% to at least 90% and increase remission from 30% to at least 80%. This 66-month program is structured into three phases: proving the core technical thesis (months 1-24), demonstrating proof-of-concept (months 25-42), and clinical translation and commercialization preparation (months 43-66). Awards will be issued as Other Transactions (OT) and are subject to a quarterly milestone payment schedule. The selection process involves a multi-stage evaluation of Solution Summaries, Full Proposals, and oral Pitches, with awards granted to those determined to be most advantageous to the government based on scientific merit, feasibility, innovation, and proposer capabilities. Key requirements for performers include securing Institutional Review Board (IRB) approval for human subjects research, implementing rigorous safety monitoring for overnight home use, and providing comprehensive FDA regulatory and intellectual property strategies. The final response deadline for proposals is October 13, 2026.

General Info

ARPA-H REST program develops closed-loop home technologies to improve insomnia treatment and remission.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

DC

Set-Aside

NONE

Documents

15

ARPA-H ISO REST Solicitation Amendment 6 August 10, 2026

PDF, High priority: read this firstamendment
High

ARPA-H ISO Solicitation ARPA-H-SOL-26-159 REST Program

PDF, High priority: read this firstrfp
High

ARPA-H ISO Solicitation ARPA-H-SOL-26-159 REST Sleep Program Amendment 2 June 18, 2026

PDF, High priority: read this firstamendment
High

ARPA-H ISO Solicitation ARPA-H-SOL-26-159 REST Sleep Program June 16 2026

PDF, High priority: read this firstiso-solicitation
High

ARPA-H ISO Solicitation ARPA-H-SOL-26-159 REST Sleep Program June 2026 Amendment 3

PDF, High priority: read this firstamendment
High

ARPA-H REST Innovative Solutions Opening Amendment 5 July 16, 2026

PDF, High priority: read this first24 pages · amendment
High

ARPA-H REST ISO Solicitation ARPA-H-SOL-26-159

PDF, High priority: read this firstrfp
High

ARPA-H REST ISO Solicitation ARPA-H-SOL26 159

PDF, High priority: read this first24 pages · rfp
High

ARPA-H-SOL-26-159 REST Innovative Solutions Opening

PDF, High priority: read this firstrfp
High

ARPA-H-SOL-26-159 REST Innovative Solutions Opening

PDF, High priority: read this firstrfp
High

ARPA-H SOL-26-159 REST Innovative Solutions Opening Amendment 1 June 16 2026

PDF, High priority: read this firstamendment
High

REST Attachment Solution Summary Format and Instructions

PDF, High priority: read this firstsolution-summary-template
High

REST_Proposal+Templates_10-2-26.zip

ZIP

REST_Proposal+Templates_9-21-26.zip

ZIP

REST_Proposal+Templates.zip

ZIP

AI Contract Breakdown

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Timeline

12 updates
PhaseClosed
Posted

Solicitation

Notice updated

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Response deadline changed from Aug 12, 2026 to Oct 13, 2026. The notice description changed.

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Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Office AddressWashington, DC, 20005, USA
Contacts

Full Description

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The Advanced Research Projects Agency for Health (ARPA-H) seeks proposals for the Restorative & health-Enhancing Sleep Time (REST) program, a bold effort to transform how poor sleep is measured and treated by enabling objective, home-based, closed-loop technologies that detect health-relevant sleep microstructures and respond to them in real time. If successful, REST will establish the technical foundation for a new generation of sleep health technologies that are objective, personalized, and capable of improving long-term health outcomes at scale.


6/16: Amendment 1 updates links within the ISO


6/18: Amendment 2 adds Section 6.5 Questions and Answers


6/24: Amendment 3 makes various edits for clarification in Sections 1-3.


7/7: Amendment 4 modifies the table in Section 3.2.1 TA1 Success Metrics.


7/16: Amendment 5 modifies additional text within the table in Section 3.2.1 TA1 Success Metrics.


8/10: Amendment 6 modifies the solicitation by breaking the Solution Summary, Proposal and Pitch into distinct categories. Solution Summaries will be reviewed on an encourage/discourage basis; Proposals will be evaluated on an invite/not invited basis; Pitches will be evaluated on a selected for negotiation/not selected basis.


8/11: Amendment 7 modifies Section 3.3 Key Program Milestones table. Changes made in Amendment 6 remain in red text to highlight important changes to solicitation process.


9/14: Amendment 8 modifies Section 4.4 Proposal Requirements and reactivates solicitation until proposal due date.


9/15: Amendment 9 adds REST Proposal Template folder as an attachment to the solicitation.


9/21: Amendment 10 revises REST Proposal Template document "REST_APPENDIX B.0_Proposal Format and Instructions".


10/2: Amendment 11 revises section 4.5 of the ISO, adds expected dates of pitch sessions, and revises "REST_APPENDIX B.0_Proposal Format and Instructions". Additionally, this amendment removed the cost breakout by task tab from both Cost Proposal spreadsheets. No substantive changes were made to the template itself. Proposers may continue to use the previously issued version of the Cost Proposal Workbook; prior versions remain fully acceptable for submission. 


10/5: Amendment 12 modifies section 4.5 of the ISO. Changes made in Amendment 11 remain in red text to highlight recent changes.

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