DoW Traumatic Brain Injury and Psychological Health, Translational Research Award
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The Translational Research Award (TRA) aims to accelerate the transformation of scientific discoveries into meaningful clinical applications, emphasizing innovative research approaches rather than incremental improvements. It explicitly excludes basic research and clinical trials, requiring applicants to provide preliminary data to support their projects. Research involving animal models must clearly justify the choice of model in relation to human clinical conditions, while studies prospectively enrolling human subjects must incorporate community-based participatory research methods. The award offers two distinct research levels to accommodate different stages of development: Research Level 1 supports refining mature concepts into tangible products ready for further testing, and Research Level 2 funds rigorous evaluation of these products in preparation for initial human studies or clinical trials. Additionally, an Early-Career Investigator Partnering Option allows two Principal Investigators to collaborate, with separate awards granted to each if funded. The program is administered by the Department of the Army under the Department of Defense, with contact and application details available through the provided channels.
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Summary: The Translational Research Award (TRA) intends to accelerate the conversion of scientific findings into impactful clinical applications. The TRA prioritizes innovative approaches over purely iterative or incremental research. Submissions focusing on minor modifications to existing standards without the intent or potential to significantly improve clinical care or patient outcomes do not meet the intent of the mechanism.
Distinctive Features: Basic research and clinical trials are prohibited. Preliminary data are required.
· For animal research, applications must describe the choice of model and its relevance to the human clinical condition.
· For research prospectively enrolling human subjects, the inclusion of community-based participatory research (CBPR) approaches is required.
· The Translational Research Award offers funding for two Research Levels. The applicant is responsible for selecting the Research Level based on the scope of the research.
○ Research Level 1: Supports the refinement of mature ideas and concepts into tangible and knowledge products positioned for further evaluation.
○ Research Level 2: Supports the rigorous evaluation of tangible and knowledge products in preparation for first-in-human studies or clinical trials.
· Early-Career Investigator Partnering Option (available for both Research Levels): This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.
