DoW Traumatic Brain Injury and Psychological Health, Translational Research Award
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Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The Traumatic Brain Injury and Psychological Health Research Program Translational Research Award (HT942526TBIPHRPTRA) is an assistance agreement administered by the Defense Health Agency Contracting Activity to accelerate the conversion of scientific findings into impactful clinical applications. The program prioritizes innovative research over iterative modifications to existing standards, specifically targeting the prevention, assessment, and treatment of psychological health conditions and traumatic brain injuries. While basic research and clinical trials are prohibited, preliminary data are required. The award offers two funding levels: Research Level 1 for refining mature concepts with a cost cap of 1.0M dollars, and Research Level 2 for rigorous evaluation in preparation for first-in-human studies with a cost cap of 2.0M dollars. An Early-Career Investigator Partnering Option is available for both levels, allowing for two Principal Investigators to receive separate awards within the specified cost caps. The maximum period of performance is four years, with a total available funding pool of approximately 9.0M dollars. Applications are evaluated through a two-tier process consisting of a peer review for technical merit and a programmatic review for military health relevance. Key evaluation factors include impact, research strategy, feasibility, and the appropriateness of the research sharing plan. Applicants must maintain active registrations in SAM.gov, eBRAP.org, and Grants.gov. Strict prohibitions are in place regarding classified research, including topics such as Havana Syndrome and directed energy. Additionally, research involving human or animal subjects requires approval from the DHA R&D Office of Research and Regulatory Compliance in addition to local institutional reviews. The application deadline is October 15, 2026, following a pre-application deadline of July 13, 2026.
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Full Description
Summary: The Translational Research Award (TRA) intends to accelerate the conversion of scientific findings into impactful clinical applications. The TRA prioritizes innovative approaches over purely iterative or incremental research. Submissions focusing on minor modifications to existing standards without the intent or potential to significantly improve clinical care or patient outcomes do not meet the intent of the mechanism.
Distinctive Features: Basic research and clinical trials are prohibited. Preliminary data are required.
· For animal research, applications must describe the choice of model and its relevance to the human clinical condition.
· For research prospectively enrolling human subjects, the inclusion of community-based participatory research (CBPR) approaches is required.
· The Translational Research Award offers funding for two Research Levels. The applicant is responsible for selecting the Research Level based on the scope of the research.
○ Research Level 1: Supports the refinement of mature ideas and concepts into tangible and knowledge products positioned for further evaluation.
○ Research Level 2: Supports the rigorous evaluation of tangible and knowledge products in preparation for first-in-human studies or clinical trials.
· Early-Career Investigator Partnering Option (available for both Research Levels): This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.
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