This Pre-Solicitation opportunity was posted on January 5, 2018. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Electrospun poly (D,L-lactide-co-glycolide) (PDLGA) scaffold

Awarded

HHS-NIH-NIDA-NOI-2018-066Federal

Submission Closed01/12/2018, 08:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541713

New

SBIR / STTR

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The USDA SBIR/STTR Topic 8.1 solicitation, managed by the National Institute of Food and Agriculture, seeks innovative technologies to enhance the health, productivity, and sustainability of national forests and grasslands. The program prioritizes the development of environmentally sound approaches to increase forest productivity, improve resource sustainability, and create value-added materials from woody resources. Specific areas of interest include sustainable bioenergy, biofuels derived from woody biomass, the impact of climate change on forest health, and the application of nanotechnology in wood-based products. Over a ten-year horizon, the program aims to increase the utilization of woody resources for high-value products and foster forest ecosystems that are more resilient to wildfires, pathogens, and climate-related disturbances. Key goals include improving the economic and environmental methods of sustainable harvesting and enhancing the growth and yield of forest species for more efficient land use. This opportunity is a total small business set-aside restricted to entities with fewer than 500 employees.

National Institute of Food and Agriculture

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Nanotechnology Orchestrated Viral Annihilation (NOVA) – DTRA

Solicitation # 5fc9b9c3-3c66-4cf1-bd23-c37a93301889

The Department of Defense, through the Defense Threat Reduction Agency, is seeking prototypes for nanotechnology-based medical countermeasures to protect warfighters from multiple viral threats. Moving away from the traditional one-virus, one-countermeasure model, this initiative aims to develop broad-spectrum, biocompatible, and biodegradable solutions capable of functioning in both pre- and post-exposure scenarios. The goal is to create a versatile platform that can neutralize various viruses while simultaneously mitigating inflammatory fallout from preexisting infections. The project is divided into three lines of effort focusing on prototype demonstration, ruggedization, and scalability. The first phase requires a prototype that demonstrates activity against at least five viruses in vitro and one virus in vivo, utilizing cellular decoy and immunomodulatory mechanisms. The second phase focuses on creating heat-stable, ruggedized formulations suitable for multiple administration routes in austere environments. Finally, the effort requires the development of a scalable manufacturing process and a defined regulatory pathway toward FDA licensure to ensure the technology can transition from nonclinical demonstration to clinical use.

Department Of Defense

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Operando Measurements for Electrochemical Surfactant-Mediated Growth Mechanisms for Interconnect MaterialsThe Department of Commerce is seeking technical research support to conduct operando electrochemical measurements focused on surfactant-mediated metal deposition processes. This effort supports the CHIPS Act project titled Electrodeposition of Interconnect Materials and Packaging, with a primary goal of understanding the mechanisms behind the electrochemical deposition of copper and alternative interconnect metals such as rhodium and iridium. The selected contractor will utilize operando measurements and surface science techniques to investigate nucleation and growth processes. Specific research will emphasize how interfacial structures and metal deposition are influenced by the co-adsorption and competitive adsorption of cations, anions, halides, surfactants, suppressors, and other additives. The work is slated to be performed in Gaithersburg.

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Theoretical/Applied Research ScientistThis subcontract for a Theoretical/Applied Research Scientist supports the Defense Advanced Research Projects Agency within the Department of Defense. The role focuses on conducting high-risk, high-reward research to secure fundamental scientific breakthroughs for prime contractors. Key responsibilities include investigating innovative approaches to drive revolutionary advances through the use of specialized simulation software and high-performance computing. The contractor is required to deliver theoretical models, validated experimental data, and scientific papers while maintaining compliance with NIST SP 800-171 standards for the protection of controlled unclassified information. This opportunity falls under NAICS code 541713 and has a response deadline of June 1, 2027.

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Magnetic resonance spectrometerThe Department of Commerce is forecasting the acquisition of an x-band continuous wave electron spin resonance spectrometer to support the Nanoscale Device Characterization Division in PML. This equipment is intended to enhance quantum-based sensing efforts by enabling the measurement of the chemical and physical properties of atomic-scale defects in solid-state materials, which is critical for applications such as magnetometry. The procurement aims to expand existing electron spin resonance infrastructure to accommodate an increasing demand for characterization services. The work will be performed in Gaithersburg, and the project is categorized under NAICS code 541713. Interested parties may contact Hannah Lee or the DOC OSDBU for further information.

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Natural Language Processing for Aviation Audio CommunicationsThe NASA SBIR/STTR Program is seeking a subcontractor to design and demonstrate the feasibility of utilizing speech-to-text and natural language processing to identify errors within controller-pilot communications. The primary objective of this effort is to implement transcription validation and error classification to improve the safety and accuracy of aviation audio communications. This project is designated as a Total Small Business Set-Aside under NAICS code 541713 and is managed by the National Aeronautics and Space Administration. Performance for this contract is centered at Moffett Field, California, with the official posting date listed as August 20, 2026.

NASA SBIR/STTR Program

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DEADLINE

Operando Measurements for Electrochemical Surfactant-Mediated Growth Mechanisms for Interconnect MaterialsThis contract seeks technical research support for the Department of Commerce to conduct operando electrochemical measurements focused on surfactant-mediated metal deposition processes. The primary objective is to support NIST research into the mechanisms of electrochemical deposition for copper and alternative interconnect metals, such as rhodium and iridium, specifically investigating nucleation and growth processes. A key area of focus involves analyzing how co-adsorption and competitive adsorption of additives, suppressors, surfactants, halides, anions, and cations influence metal deposition and interfacial structure. This initiative is part of the CHIPS Act project titled Electrodeposition of Interconnect Materials and Packaging and will be performed in Gaithersburg, Maryland. The opportunity is designated as a total small business set-aside under NAICS code 541713. Interested parties can coordinate through the point of contact, William Clark, regarding this forecast for laboratory program support.

AD for Laboratory Programs

POSTED

DEADLINE

Nuclear Technologies Development and Integration SupportThe National Nuclear Security Administration, an agency of the Department of Energy, has issued a forecast for Nuclear Technologies Development and Integration Support. This requirement falls under NAICS code 541713 and is slated for performance in Maryland. The current incumbent contractor for these services is the Johns Hopkins University Applied Physics Laboratory LLC. Interested parties can coordinate with Chelsea Murphy, the Small Business Program Manager, regarding this opportunity. The forecast was posted on August 16, 2026, and is categorized as an other type of set-aside.

National Nuclear Security Administration

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STATE OF THE ART (SOTA) MICROELECTRONICS (ME) ADOPTION BROAD AGENCY ANNOUNCEMENT (BAA) FULL TEXT GENERAL ANNOUNCEMENT

Solicitation # 26S1358

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Department Of The Air Force

POSTED

DEADLINE

ERIS Shopping Notice: High Duty Cycle High Energy Lasers (HEL) for SWaP-Constrained Systems

Solicitation # DARPA-SN-26-82

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Defense Advanced Research Projects Agcy

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National Science Foundation

POSTED

DEADLINE

NSF 26-510 | Augmented Virtual and Mixed Reality (AV/VR/MR) — Differentiated Hardware Technologies for AR/VR/MR

Solicitation # nsf-seedfund-AV-AV1_STTR

The National Science Foundation is seeking proposals under solicitation nsf-seedfund-AV-AV1_STTR for the development of innovative and differentiated hardware and software within the Augmented, Virtual, and Mixed Reality sectors. This initiative targets early-stage entrepreneurs and startups aiming to translate research-based insights into scalable, commercial applications. Key focus areas include the integration of AI for education, workforce development, health and wellbeing, and the creation of platforms for virtual collaboration and experiential learning. This opportunity is a total small business set-aside, specifically mandated for SBIR/STTR participants with fewer than 500 employees. The primary objective is to support the creation of novel technologies that enable shared experiences and provide tools for upskilling an aging workforce or improving general wellness. Interested parties can find further details through the National Science Foundation seed fund portal.

National Science Foundation

POSTED

5 months ago

DEADLINE

N/A

AI Contract Overview

The National Institute on Drug Abuse, specifically the National Center for Advancing Translational Sciences, intends to award a non-competitive contract for customized Electrospun poly (D,L-lactide-co-glycolide) (PDLGA) scaffolds manufactured by Biosurfaces, Inc. This procurement is conducted under Simplified Acquisition Procedures and is classified under NAICS code 541715. The required scaffolds must meet strict physical specifications, including dimensions of 9cm by 10cm, a thickness of less than 10 micrometers, and a pore size of less than 1.0 micrometer to prevent cell migration and leakage for three weeks. The product must be biocompatible, biodegradable, and capable of supporting cell monolayer formation and bioprinting with bioink. Interested parties must submit their capability statements and price quotes to Contract Specialist Stuart Kern by January 12, 2018. Required documentation includes the unit price, shipping costs, delivery terms, DUNS number, Taxpayer Identification Number, and certification of business size. All offerors must maintain an active registration in the System for Award Management. While this is a pre-solicitation notice of intent to award without full competition, the government will review responses to determine if the procurement should proceed on a non-competitive basis or be opened for competitive bidding. Delivery is expected within two to three weeks after the receipt of the order.

General Info

Agency

N/A

Contract Value

$26,761

NAICS

541713 - Research and Development in Nanotechnology

Place of Performance

National Center for Advancing Translational Sciences (NCATS) 9800 Medical Center Drive, ROCKVILLE, MD, 20850, USA

Set-Aside

NONE

Awardee

BIOSURFACES INC

Award Issued Date

01/16/2018, 12:00:00 AM UTC

Documents

No documents available

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Timeline

PhaseAwarded

PostedJan 5

Presolicitation

AwardedJan 16

Contract was awarded

Submission Closed

01/12/2018, 08:00:00 PM UTC

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Organization & Contact Information

AgencyN/A

Contacts1 person available

OfficeN/A

Organization / Agency

N/A

Office AddressN/A

Contacts

Stuart G. KernContract Specialist

contact@example.gov

+1 (555) 000-0000

Full Description

INTRODUCTION PURSUANT TO FAR Subpart 5.2-Synopses of Proposed Contract Actions, THIS IS A PRE-SOLICITATION NOTICE OF A PROPOSED CONTRACT ACTION. THIS IS A PRE-SOLICITATION NON-COMPETITIVE NOTICE OF INTENT TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Center for Advancing Translational Sciences (NCATS) Section within the National Institute on Drug Abuse (NIDA) Office of Acquisition intends to negotiate and award a contract for Electrospun poly (D,L-lactide-co-glycolide) (PDLGA) scaffold. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 541715 with a Size Standard of 1,000 employees. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses of the Federal acquisition Requlation (FAR) in effect through the Federal Acquisition Circular (FAC) 2005-96 (dated November 6, 2017). STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source. DESCRIPTION OF REQUIREMENT Brand Name: Electrospun poly (D,L-lactide-co-glycolide) (PDLGA) scaffold Manufacturer's name: Biosurfaces, Inc. Model, type, catalog number: The item is customized. Physical/functional/performance features of the product: 9cm (W) x 10cm (L) including ~500nm of electrospun nanofibers. Thickness is less than 10 - m. Pore size is less than 1.0 - m diameter to prevent from cell migration and to separate culture media from top to bottom without leakage for 3 weeks using pre- and post- thermal process. Capable of maintaining mechanical strength at least for 3 weeks. Half degradation time is about a month. Biocompatible, biodegradable, and bioprintable with bioink. Capable of cell monolayer formation on the surface. Features of the product that are essential to the government's needs: Small pore size enhances tissue engineering capability including multi cell types. Biodegradation of scaffolds helps integration of 3D tissue layers, which is one of key features to mimic cell-cell communications within tissues in various pathological conditions. DELIVERY DATE 2-3 weeks ARO CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents that believe that they are manufacturers or authorized resellers of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by 3:00 PM Eastern, January 12, 2018 and must reference number HHS-NIH-NIDA-NOI-2018-066. Responses must be submitted electronically to Stuart Kern, Contract Specialist, at contact@example.gov. FAX requests are not accepted. "All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency."