Evaluation and Conduct of Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

This research and development contract, awarded by the National Institute of Environmental Health Sciences under the Department of Health and Human Services, focuses on the evaluation and conduct of computational and alternative toxicological methods. The primary objective is to utilize New Approach Methodologies, including in silico, in chemico, in vitro, and ex vivo techniques, to assess chemical hazards and risks without the use of animal testing. Key research priorities include acute toxicity, carcinogenicity, ecotoxicity, developmental neurotoxicity, and population susceptibility. The contract, identified by solicitation number 75N94026C00002, is designated as a total small business set-aside under NAICS code 541715. Managed out of Morrisville, North Carolina, the initiative aims to advance non-animal testing frameworks to enhance the accuracy and efficiency of toxicological risk assessments.