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Expanding the Therapeutic Pipeline for Treating and Preventing Alzheimer's Disease and Related Dementias: Preclinical Validation and Drug Discovery for Novel Candidate Targets (U01 Clinical Trial Not Allowed)

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute on Aging within the Department of Health and Human Services is planning to release a Notice of Funding Opportunity under the U01 activity code to support research on Alzheimer's disease and related dementias. This initiative focuses on the preclinical validation of drug targets and early-stage drug discovery involving small molecules, biologics, and other emerging therapeutic modalities. While applications are not currently being accepted, this forecast serves as a notification for investigators with expertise in drug discovery to establish collaborations and develop projects. The effort aims to expand the therapeutic pipeline for the treatment and prevention of these conditions through the identification and validation of novel candidate targets.

General Info

NIA plans funding for early-stage Alzheimer's drug discovery, excluding clinical trials, announcing March 2026.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
NIA Scientific Contact
contact@example.gov

Full Description

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The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on Alzheimer's disease (AD) and AD-related dementias (ADRD) drug target validation and early-stage drug discovery against novel targets. This NOFO will utilize the U01 activity code. The NOFO will support rigorous preclinical AD/ADRD drug target validation and early-stage drug discovery of small molecules, biologic, and emerging therapeutic modalities. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise and insights into AD/ADRD and drug discovery are encouraged to begin to consider applying for this new NOFO.

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