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Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) plans to issue a Notice of Funding Opportunity for its Exploratory Clinical Trials Grants Program, which aims to support research advancing prevention, diagnosis, and treatment in rheumatic, musculoskeletal, and skin diseases. This program focuses on short-term, interventional clinical trials that range from proof-of-concept and first-in-human studies to Phase I and Phase II trials. Projects must align with NIH clinical trial definitions and be feasible within the program’s time and budget constraints. The initiative prioritizes the translation of promising laboratory or early human research outcomes into clinical practice to improve patient outcomes and function. The types of studies sought include early-stage clinical trials that assess safety, tolerability, efficacy, or dosing of drugs, biologics, devices, behavioral interventions, or physical therapies. This funding also supports trials generating preliminary data to inform larger studies, trials addressing rare diseases with limited patient populations, and investigations determining the predictive value of biomarkers. The program is managed by the National Institutes of Health under the Department of Health and Human Services, with inquiries directed to the NIAMS contact email provided. The overarching goal is to facilitate clinical research that leads to meaningful improvements in the management of arthritis and related musculoskeletal and skin conditions.

General Info

NIAMS funding supports early-phase clinical trials advancing treatment of arthritis and musculoskeletal diseases.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
National Institute of Arthritis and Musculoskeletal and Skin Diseases
contact@example.gov

Full Description

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The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for Exploratory Clinical Trials Grants Program in the mission areas of NIAMS. The goal of the NIAMS clinical trial program is to support research leading to the prevention or reduction of symptoms and improve outcomes and function in patients with rheumatic, musculoskeletal, or skin conditions or diseases. The purpose of the Exploratory Clinical Trials Grants Program is to foster clinical trials that will lead to clinically meaningful improvements in prevention, diagnosis, or treatment of these conditions or diseases.

This Exploratory Clinical Trials Grants Program is designed to facilitate the execution of short-term, interventional studies. The Program is intended to support a range of exploratory studies, from proof-of-concept/first in human to Phase I and Phase II clinical trials. Such studies must meet the NIH definition of a clinical trial and be feasible within the time and budget constraints of this NOFO. A high priority is the use of such studies to stimulate the translation of promising research developments from laboratory, preclinical, and early human testing into clinical practice.

Examples of research areas of interest include, but are not limited to:

  • Conducting early-stage clinical trials, such as but not limited to; first in human, dose-finding or escalation/tolerability/safety/efficacy studies with drugs, biologics, devices, behavioral interventions, and/or physical therapy for treatment of arthritis, musculoskeletal, or skin conditions or diseases.
  • Clinical trials to provide data required to support a future, more robust clinical trial whose aim is to help establish the safety and efficacy or effectiveness of an intervention.
  • Clinical trials in rare diseases where the number of potential study participants is limited.
  • Clinical trials to determine the predictive value of a potential biomarker. 

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