This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on June 9, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
FDA - Intent to Sole Source Molecular Operating Environment
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The U.S. Food and Drug Administration (FDA) plans to award a sole source contract to Chemical Computing Group ULC to acquire the Molecular Operating Environment (MOE) software. This advanced molecular modeling and cheminformatics platform will enhance the Division of Applied Regulatory Science’s analytical capabilities by enabling three-dimensional structural analyses that are critical for more robust evaluation of adverse drug reactions. The contract will cover a base year from June 29, 2026, to June 28, 2027, with four additional one-year option periods extending through June 28, 2031. This sole source procurement is justified on the basis that Chemical Computing Group ULC is uniquely capable of meeting the government’s requirements, including molecular docking, computational chemical descriptor updates, chemical database management, and the modeling of diverse molecular interactions. Due to proprietary licensing agreements and warranty considerations, no other suppliers can fulfill these needs. While this notice invites other potential sources to submit capability statements by June 16, 2026, the government retains full discretion on whether to compete the acquisition and makes clear this is not a solicitation. The contract will be managed through the Omas Strategic Buying Center within the Department of Health and Human Services, with performance taking place in Silver Spring, Maryland.
General Info
Agency
NAICS
Place of Performance
Silver Spring, MD, 20993, USASet-Aside
Documents
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Timeline
Submission Closed
Organization & Contact Information
Full Description
NOTICE OF INTENT TO SOLE SOURCE
The U.S. Food and Drug Administration intends to award a sole source contract to Chemical Computing Group ULC to enhance the Division of Applied Regulatory Science (DARS) analytical capabilities beyond traditional two-dimensional (2D) methods. The Molecular Operating Environment (MOE), a comprehensive cheminformatics and molecular modeling software platform enables three-dimensional (3D) structural analysis and representation, which has proven essential for conducting more robust evaluations of adverse drug reactions that cannot be adequately assessed through 2D approaches alone.
The anticipated period of performance will consist of a base year, plus four one-year option periods.
Base Period : 06/29/2026 to 06/28/2027
Option Period One: 06/29/2027 to 06/28/2028
Option Period Two: 06/29/2028 to 06/28/2029
Option Period Three: 06/29/2029 to 06/28/2030
Option Period Four: 06/29/2030 to 06/28/2031
The award will be a single source procurement awarded to Chemical Computing Group ULC, in accordance with RFO-FAR 6.103-1 Only one responsible source and no other supplies or services will satisfy agency requirements. Contracting Officers may solicit from only one source if the circumstances of the contract action deem that only one source is reasonably available based on licensing agreements and warranty coverage on specialized equipment.
Only one source, Chemical Computing Group ULC, is capable of fulfilling the Government’s requirement to provide the molecular modeling software package to communicate and provide customizable molecular docking models, computational models updating chemical descriptors, support chemical database management, and provide modeling diverse types of molecules and molecular interactions (organic, metallic, biomolecules).
This notice is not a solicitation or a request for offers. Any potential sources other than Chemical Computing Group ULC may submit a capability statement via email to Carlton Taylor, at carlton.taylor@hhs.gov by 12:00 PM EST on Tuesday June 16, 2026.
Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. Oral communications are not acceptable in response to this notice.
A determination by the Government not to compete the proposed procurement based on responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. A solicitation will not be issued.